Terms: = Leukemia AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716 AND Treatment
176 results:
1. High throughput screening aids clinical decision-making in refractory acute myeloid leukaemia.
Jessop SJ; Fuentos-Bolanos N; Mayoh C; Dolman MEM; Tax G; Wong-Erasmus M; Ajuyah P; Tyrell V; Marshall GM; Ziegler DS; Lau LMS
Cancer Rep (Hoboken); 2024 Apr; 7(4):e2061. PubMed ID: 38662349
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2. Efficacy and Safety in Early application of Ruxolinitib for high-risk: Acute lymphoblastic leukemia to prevent GVHD and recurrence after allogeneic hematopoietic stem cell transplantation.
Cheng Q; Tang Y; Liu F; Li X; Fang D
Transpl Immunol; 2024 Apr; 83():101978. PubMed ID: 38302005
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3. Whole-genome CRISPR screening identifies molecular mechanisms of PD-L1 expression in adult T-cell leukemia/lymphoma.
Chiba M; Shimono J; Suto K; Ishio T; Endo T; Goto H; Hasegawa H; Maeda M; Teshima T; Yang Y; Nakagawa M
Blood; 2024 Apr; 143(14):1379-1390. PubMed ID: 38142436
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4. CALCRL induces resistance to daunorubicin in acute myeloid leukemia cells through upregulation of XRCC5/TYK2/jak1 pathway.
Tang S; Li S; Shi X; Sheng L; Mu Q; Wang Y; Zhu H; Xu K; Zhou M; Xu Z; Wu A; Ouyang G
Anticancer Drugs; 2024 Feb; 35(2):163-176. PubMed ID: 37948318
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5. The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Di Giorgio C; Bellini R; Lupia A; Massa C; Urbani G; Bordoni M; Marchianò S; Rosselli R; De Gregorio R; Rapacciuolo P; Sepe V; Morretta E; Monti MC; Moraca F; Cari L; Ullah KRS; Natalizi N; Graziosi L; Distrutti E; Biagioli M; Catalanotti B; Donini A; Zampella A; Fiorucci S
Cell Oncol (Dordr); 2024 Apr; 47(2):695-710. PubMed ID: 37945798
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6. The JAK3
Lahera A; Vela-Martín L; Fernández-Navarro P; Llamas P; López-Lorenzo JL; Cornago J; Santos J; Fernández-Piqueras J; Villa-Morales M
Mol Carcinog; 2024 Jan; 63(1):5-10. PubMed ID: 37712558
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7. The jak1/2 inhibitor ruxolitinib in patients with COVID-19 triggered hyperinflammation: the RuxCoFlam trial.
Hammersen J; Birndt S; Döhner K; Reuken P; Stallmach A; Sauerbrey P; La Rosée F; Pfirrmann M; Fabisch C; Weiss M; Träger K; Bremer H; Russo S; Illerhaus G; Drömann D; Schneider S; La Rosée P; Hochhaus A
Leukemia; 2023 Sep; 37(9):1879-1886. PubMed ID: 37507425
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8. Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic leukemia.
Sun X; Liu X; Li Y; Shi X; Li Y; Tan R; Jiang Y; Sui X; Ge X; Xu H; Wang X; Fang X
Oncology; 2024; 102(1):85-98. PubMed ID: 37437551
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9. Achievements and future outlook for JAK inhibitors in polycythaemia vera.
Cakmak I; Harrison C
Expert Opin Pharmacother; 2023; 24(13):1491-1496. PubMed ID: 37343285
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10. Rare Lymphomas: Getting "a Bit Ahead".
Cancer Discov; 2023 Aug; 13(8):OF4. PubMed ID: 37294133
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11. jak1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling.
Grant AH; Rodriguez AC; Rodriguez Moncivais OJ; Sun S; Li L; Mohl JE; Leung MY; Kirken RA; Rodriguez G
Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047778
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12. Momelotinib long-term safety and survival in myelofibrosis: integrated analysis of phase 3 randomized controlled trials.
Verstovsek S; Mesa R; Gupta V; Lavie D; Dubruille V; Cambier N; Platzbecker U; Hus M; Xicoy B; Oh ST; Kiladjian JJ; Vannucchi AM; Gerds A; Egyed M; Mayer J; Sacha T; Kawashima J; Morris M; Huang M; Harrison C
Blood Adv; 2023 Jul; 7(14):3582-3591. PubMed ID: 37042865
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13. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte-endothelial proadhesive interactions.
Beckman JD; DaSilva A; Aronovich E; Nguyen A; Nguyen J; Hargis G; Reynolds D; Vercellotti GM; Betts B; Wood DK
J Thromb Haemost; 2023 May; 21(5):1366-1380. PubMed ID: 36738826
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14. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study.
Verstovsek S; Gerds AT; Vannucchi AM; Al-Ali HK; Lavie D; Kuykendall AT; Grosicki S; Iurlo A; Goh YT; Lazaroiu MC; Egyed M; Fox ML; McLornan D; Perkins A; Yoon SS; Gupta V; Kiladjian JJ; Granacher N; Lee SE; Ocroteala L; Passamonti F; Harrison CN; Klencke BJ; Ro S; Donahue R; Kawashima J; Mesa R;
Lancet; 2023 Jan; 401(10373):269-280. PubMed ID: 36709073
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15. Interferon gamma regulates a complex pro-survival signal network in chronic lymphocytic leukemia.
Chen Y; Shao X; Yang H; Ren L; Cui Y; Zhang W; Macip S; Meng X
Eur J Haematol; 2023 Apr; 110(4):435-443. PubMed ID: 36576398
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16. Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells
Li H; Sun N; Zhu Y; Wang W; Cai M; Luo X; Xia W; Quan S
Eur J Histochem; 2023 Jan; 67(1):. PubMed ID: 36546418
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17. Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes.
Bolouri H; Ries RE; Wiedeman AE; Hylkema T; Scheiding S; Gersuk VH; O'Brien K; Nguyen QA; Smith JL; Alice Long S; Meshinchi S
Nat Commun; 2022 Nov; 13(1):7186. PubMed ID: 36418348
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18. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the treatment of Pancreatic Adenocarcinoma.
Di Giorgio C; Lupia A; Marchianò S; Bordoni M; Bellini R; Massa C; Urbani G; Roselli R; Moraca F; Sepe V; Catalanotti B; Morretta E; Monti MC; Biagioli M; Distrutti E; Zampella A; Fiorucci S
Cells; 2022 Nov; 11(21):. PubMed ID: 36359879
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19. A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.
Yu X; Ma H; Li B; Ji Y; Du Y; Liu S; Li Z; Hao Y; Tian S; Zhao C; Du Q; Jin Z; Zhu X; Tian Y; Chen X; Sun X; Yang C; Zhu F; Ju J; Zheng Y; Zhang W; Wang J; Yang T; Wang X; Li J; Xu X; Du S; Lu H; Ma F; Zhang H; Zhang Y; Zhang X; Hu S; He S
Blood; 2023 Mar; 141(9):1070-1086. PubMed ID: 36356302
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20. IL-7: Comprehensive review.
Winer H; Rodrigues GOL; Hixon JA; Aiello FB; Hsu TC; Wachter BT; Li W; Durum SK
Cytokine; 2022 Dec; 160():156049. PubMed ID: 36201890
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