BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND JAK3, L-JAK, 3718, ENSG00000105639, P52333, JAKL, JAK-3, LJAK, JAK3_HUMAN AND Treatment
80 results:

  • 1. treatment patterns, clinical outcomes and gene mutation characteristics of hepatitis B virus-associated mantle cell lymphoma.
    Feng J; Fei Y; Gao M; Meng X; Zeng D; Zou D; Ye H; Liang Y; Sun X; Liang R; Zhou H; Wang X; Zhang H
    Hematol Oncol; 2024 May; 42(3):e3268. PubMed ID: 38676394
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. N-Acetylcysteine Alters Disease Progression and Increases Janus Kinase Mutation Frequency in a Mouse Model of Precursor B-Cell Acute Lymphoblastic leukemia.
    Sams MP; Iansavitchous J; Astridge M; Rysan H; Xu LS; Rodrigues de Oliveira B; DeKoter RP
    J Pharmacol Exp Ther; 2024 Mar; 389(1):40-50. PubMed ID: 38336380
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The jak3
    Lahera A; Vela-Martín L; Fernández-Navarro P; Llamas P; López-Lorenzo JL; Cornago J; Santos J; Fernández-Piqueras J; Villa-Morales M
    Mol Carcinog; 2024 Jan; 63(1):5-10. PubMed ID: 37712558
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Partial response to venetoclax and ruxolitinib combination in a case of refractory T-prolymphocytic leukemia.
    Brothers J; Castillo DR; Jeon WJ; Joung B; Linhares Y
    Hematology; 2023 Dec; 28(1):2237342. PubMed ID: 37485976
    [No Abstract]    [Full Text] [Related]  

  • 5. Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic leukemia.
    Sun X; Liu X; Li Y; Shi X; Li Y; Tan R; Jiang Y; Sui X; Ge X; Xu H; Wang X; Fang X
    Oncology; 2024; 102(1):85-98. PubMed ID: 37437551
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. JAK1 Pseudokinase V666G Mutant Dominantly Impairs jak3 Phosphorylation and IL-2 Signaling.
    Grant AH; Rodriguez AC; Rodriguez Moncivais OJ; Sun S; Li L; Mohl JE; Leung MY; Kirken RA; Rodriguez G
    Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047778
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. 2-Aminopyrimidine derivatives as selective dual inhibitors of JAK2 and FLT3 for the treatment of acute myeloid leukemia.
    Xu S; Zhu Y; Meng J; Li C; Zhu Z; Wang C; Gu YC; Han L; Wen J; Tong M; Shi X; Hou Y; Liu Y; Zhao Y
    Bioorg Chem; 2023 May; 134():106442. PubMed ID: 36878064
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. IL-7: Comprehensive review.
    Winer H; Rodrigues GOL; Hixon JA; Aiello FB; Hsu TC; Wachter BT; Li W; Durum SK
    Cytokine; 2022 Dec; 160():156049. PubMed ID: 36201890
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.
    Zhang H; Zhan Q; Wang X; Gao F; Yu J; Wang J; Fu W; Wang P; Wei X; Zhang L
    Ann Hematol; 2022 Dec; 101(12):2583-2600. PubMed ID: 36181538
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The mRNA Expression of
    Lak ER; Tamaddon G; Ramzi M; Ranjbaran R; Abedi E; Sharifzadeh S
    Cardiovasc Hematol Agents Med Chem; 2023; 21(1):67-76. PubMed ID: 35993473
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Transformation from polycythemia vera to acute promyelocytic leukemia: Case report and literature review.
    Li WW; Sui XF; Fan S; Xu H; Wang CL; Wang FY; Mo XD
    Medicine (Baltimore); 2022 Aug; 101(32):e30064. PubMed ID: 35960050
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Janus kinase (JAK) inhibitors in the treatment of neoplastic and inflammatory disorders.
    Roskoski R
    Pharmacol Res; 2022 Sep; 183():106362. PubMed ID: 35878738
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Discovery of Hexahydrofuro[3,2-
    Li S; Si H; Song X; Lei C; He X; Wang J; Liu Y; Zhou Y; Song JG; Peng L; Tang X; Chan S; Ren X; Tu Z; Li Z; Wang Z; Zhang Z; Ding K
    J Med Chem; 2022 Aug; 65(15):10674-10690. PubMed ID: 35860875
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. jak3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia.
    Bodaar K; Yamagata N; Barthe A; Landrigan J; Chonghaile TN; Burns M; Stevenson KE; Devidas M; Loh ML; Hunger SP; Wood B; Silverman LB; Teachey DT; Meijerink JP; Letai A; Gutierrez A
    Leukemia; 2022 Jun; 36(6):1499-1507. PubMed ID: 35411095
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. PHF6 and jak3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.
    Yuan S; Wang X; Hou S; Guo T; Lan Y; Yang S; Zhao F; Gao J; Wang Y; Chu Y; Shi J; Cheng T; Yuan W
    Leukemia; 2022 Feb; 36(2):370-382. PubMed ID: 34465864
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Mutant
    Goldberg L; Negi V; Chung YJ; Onozawa M; Zhu YJ; Walker RL; Pierce R; Patel DP; Krausz KW; Gonzalez FJ; Goodell MA; Rodriguez BAT; Meltzer PS; Aplan PD
    Cancer Res; 2021 Oct; 81(19):5033-5046. PubMed ID: 34321240
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. How much has allogeneic stem cell transplant-related mortality improved since the 1980s? A retrospective analysis from the EBMT.
    Penack O; Peczynski C; Mohty M; Yakoub-Agha I; Styczynski J; Montoto S; Duarte RF; Kröger N; Schoemans H; Koenecke C; Peric Z; Basak GW
    Blood Adv; 2020 Dec; 4(24):6283-6290. PubMed ID: 33351121
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Failure of tofacitinib to achieve an objective response in a
    Wong J; Wall M; Corboy GP; Taubenheim N; Gregory GP; Opat S; Shortt J
    Cold Spring Harb Mol Case Stud; 2020 Aug; 6(4):. PubMed ID: 32843425
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Initial absolute monocyte count as an immune biomarker for clinical response in acute myeloid leukemia with monocytic differentiation.
    Embaby A; Fathy A; Al-Akkad M; Baraka A; Ibrahim T; Zidan N; Refaat M; Elsheikh H
    J Egypt Natl Canc Inst; 2020 Aug; 32(1):33. PubMed ID: 32743788
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The clinical mutatome of core binding factor leukemia.
    Opatz S; Bamopoulos SA; Metzeler KH; Herold T; Ksienzyk B; Bräundl K; Tschuri S; Vosberg S; Konstandin NP; Wang C; Hartmann L; Graf A; Krebs S; Blum H; Schneider S; Thiede C; Middeke JM; Stölzel F; Röllig C; Schetelig J; Ehninger G; Krämer A; Braess J; Görlich D; Sauerland MC; Berdel WE; Wörmann BJ; Hiddemann W; Spiekermann K; Bohlander SK; Greif PA
    Leukemia; 2020 Jun; 34(6):1553-1562. PubMed ID: 31896782
    [TBL] [Abstract] [Full Text] [Related]  


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