Terms: = Leukemia AND KDM5A, RBBP2, 5927, JARID1A, ENSG00000073614
34 results:
1. Critical role of MXRA7 in differentiation blockade in human acute promyelocytic leukemia cells.
Sun Z; Lin D; Shen Y; Ma K; Wang B; Liu H; Chen S; Wu D; Wang Y
Exp Hematol; 2023; 125-126():45-54. PubMed ID: 37419299
[TBL] [Abstract] [Full Text] [Related]
2. The pediatric leukemia oncoprotein NUP98-kdm5a induces genomic instability that may facilitate malignant transformation.
Domingo-Reinés J; Montes R; Garcia-Moreno A; Gallardo A; Sanchez-Manas JM; Ellson I; Lamolda M; Calabro C; López-Escamez JA; Catalina P; Carmona-Sáez P; Real PJ; Landeira D; Ramos-Mejia V
Cell Death Dis; 2023 Jun; 14(6):357. PubMed ID: 37301844
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3. Comprehensive molecular and clinical characterization of
Bertrums EJM; Smith JL; Harmon L; Ries RE; Wang YJ; Alonzo TA; Menssen AJ; Chisholm KM; Leonti AR; Tarlock K; Ostronoff F; Pogosova-Agadjanyan EL; Kaspers GJL; Hasle H; Dworzak M; Walter C; Muhlegger N; Morerio C; Pardo L; Hirsch B; Raimondi S; Cooper TM; Aplenc R; Gamis AS; Kolb EA; Farrar JE; Stirewalt D; Ma X; Shaw TI; Furlan SN; Brodersen LE; Loken MR; Van den Heuvel-Eibrink MM; Zwaan CM; Triche TJ; Goemans BF; Meshinchi S
Haematologica; 2023 Aug; 108(8):2044-2058. PubMed ID: 36815378
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4. Gene mutation analysis using next-generation sequencing and its clinical significance in patients with myeloid neoplasm: A multi-center study from China.
Li J; Pei L; Liang S; Xu S; Wang Y; Wang X; Liao Y; Zhan Q; Cheng W; Yang Z; Tang X; Zhang H; Xiao Q; Chen J; Liu L; Wang L
Cancer Med; 2023 Apr; 12(8):9332-9350. PubMed ID: 36799265
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5. Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.
Chandra B; Michmerhuizen NL; Shirnekhi HK; Tripathi S; Pioso BJ; Baggett DW; Mitrea DM; Iacobucci I; White MR; Chen J; Park CG; Wu H; Pounds S; Medyukhina A; Khairy K; Gao Q; Qu C; Abdelhamed S; Gorman SD; Bawa S; Maslanka C; Kinger S; Dogra P; Ferrolino MC; Di Giacomo D; Mecucci C; Klco JM; Mullighan CG; Kriwacki RW
Cancer Discov; 2022 Apr; 12(4):1152-1169. PubMed ID: 34903620
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6. Pharmacological inhibition of kdm5a for cancer treatment.
Yang GJ; Wu J; Miao L; Zhu MH; Zhou QJ; Lu XJ; Lu JF; Leung CH; Ma DL; Chen J
Eur J Med Chem; 2021 Dec; 226():113855. PubMed ID: 34555614
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7. kdm5a suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2.
Xu S; Wang S; Xing S; Yu D; Rong B; Gao H; Sheng M; Tan Y; Sun X; Wang K; Xue K; Shi Z; Lan F
Blood Adv; 2021 Sep; 5(17):3241-3253. PubMed ID: 34448811
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8. Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of kdm5a at DNA lesions.
Kumbhar R; Sanchez A; Perren J; Gong F; Corujo D; Medina F; Devanathan SK; Xhemalce B; Matouschek A; Buschbeck M; Buck-Koehntop BA; Miller KM
J Cell Biol; 2021 Jul; 220(7):. PubMed ID: 34003252
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9. Clinical impact of genomic characterization of 15 patients with acute megakaryoblastic leukemia-related malignancies.
Lalonde E; Rentas S; Wertheim G; Cao K; Surrey LF; Lin F; Zhao X; Obstfeld A; Aplenc R; Luo M; Li MM
Cold Spring Harb Mol Case Stud; 2021 Apr; 7(2):. PubMed ID: 33832921
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10. Conditionally immortalised leukaemia initiating cells co-expressing Hoxa9/Meis1 demonstrate microenvironmental adaptation properties ex vivo while maintaining myelomonocytic memory.
Stahlhut M; Ha TC; Takmakova E; Morgan MA; Schwarzer A; Schaudien D; Eder M; Schambach A; Kustikova OS
Sci Rep; 2021 Mar; 11(1):5294. PubMed ID: 33674652
[TBL] [Abstract] [Full Text] [Related]
11. Modeling and targeting of erythroleukemia by hematopoietic genome editing.
Iacobucci I; Qu C; Varotto E; Janke LJ; Yang X; Seth A; Shelat A; Friske JD; Fukano R; Yu J; Freeman BB; Kennedy JA; Sperling AS; Zheng R; Wang Y; Jogiraju H; Dickerson KM; Payne-Turner D; Morris SM; Hollis ES; Ghosn N; Haggard GE; Lindsley RC; Ebert BL; Mullighan CG
Blood; 2021 Mar; 137(12):1628-1640. PubMed ID: 33512458
[TBL] [Abstract] [Full Text] [Related]
12. Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.
Zhang Y; Guo Y; Gough SM; Zhang J; Vann KR; Li K; Cai L; Shi X; Aplan PD; Wang GG; Kutateladze TG
Nat Commun; 2020 Jul; 11(1):3339. PubMed ID: 32620764
[TBL] [Abstract] [Full Text] [Related]
13. CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J; Barbosa IAM; Eder T; Brandstoetter T; Schmidt L; Maurer B; Troester S; Pham HTT; Sagarajit M; Ebner J; Manhart G; Aslan E; Terlecki-Zaniewicz S; Van der Veen C; Hoermann G; Duployez N; Petit A; Lapillonne H; Puissant A; Itzykson R; Moriggl R; Heuser M; Meisel R; Valent P; Sexl V; Zuber J; Grebien F
Blood; 2020 Jul; 136(4):387-400. PubMed ID: 32344427
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14. Human models of NUP98-kdm5a megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities.
Cardin S; Bilodeau M; Roussy M; Aubert L; Milan T; Jouan L; Rouette A; Laramée L; Gendron P; Duchaine J; Decaluwe H; Spinella JF; Mourad S; Couture F; Sinnett D; Haddad É; Landry JR; Ma J; Humphries RK; Roux PP; Hébert J; Gruber TA; Wilhelm BT; Cellot S
Blood Adv; 2019 Nov; 3(21):3307-3321. PubMed ID: 31698461
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15. Patients aged less than 3 years with acute myeloid leukaemia characterize a molecularly and clinically distinct subgroup.
Hara Y; Shiba N; Yamato G; Ohki K; Tabuchi K; Sotomatsu M; Tomizawa D; Kinoshita A; Arakawa H; Saito AM; Kiyokawa N; Tawa A; Horibe K; Taga T; Adachi S; Taki T; Hayashi Y
Br J Haematol; 2020 Feb; 188(4):528-539. PubMed ID: 31612466
[TBL] [Abstract] [Full Text] [Related]
16. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S; Yim S; Park H
Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
[TBL] [Abstract] [Full Text] [Related]
17. [Prognostic significance of chimeric fusion gene analysis in pediatric acute megakaryoblastic leukemia].
Tamefusa K; Fukutake K; Ishida H; Tamura A; Endo M; Hamamoto K; Koga Y; Yamada M; Kanamitsu K; Fujiwara K; Washio K; Shimada A
Rinsho Ketsueki; 2019; 60(2):99-105. PubMed ID: 30842387
[TBL] [Abstract] [Full Text] [Related]
18. CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.
Kralickova P; Milota T; Litzman J; Malkusova I; Jilek D; Petanova J; Vydlakova J; Zimulova A; Fronkova E; Svaton M; Kanderova V; Bloomfield M; Parackova Z; Klocperk A; Haviger J; Kalina T; Sediva A
Front Immunol; 2018; 9():3135. PubMed ID: 30723478
[No Abstract] [Full Text] [Related]
19. [Genetic aberrations and new treatment strategies for pediatric acute myeloid leukemia].
Shiba N
Rinsho Ketsueki; 2018; 59(10):2260-2267. PubMed ID: 30305534
[TBL] [Abstract] [Full Text] [Related]
20. Targeting histone demethylases kdm5a and KDM5B in AML cancer cells: A comparative view.
Shokri G; Doudi S; Fathi-Roudsari M; Kouhkan F; Sanati MH
Leuk Res; 2018 May; 68():105-111. PubMed ID: 29602065
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