Terms: = Leukemia AND KDM5A, RBBP2, 5927, JARID1A, ENSG00000073614 AND Treatment
16 results:
1. Critical role of MXRA7 in differentiation blockade in human acute promyelocytic leukemia cells.
Sun Z; Lin D; Shen Y; Ma K; Wang B; Liu H; Chen S; Wu D; Wang Y
Exp Hematol; 2023; 125-126():45-54. PubMed ID: 37419299
[TBL] [Abstract] [Full Text] [Related]
2. The pediatric leukemia oncoprotein NUP98-kdm5a induces genomic instability that may facilitate malignant transformation.
Domingo-Reinés J; Montes R; Garcia-Moreno A; Gallardo A; Sanchez-Manas JM; Ellson I; Lamolda M; Calabro C; López-Escamez JA; Catalina P; Carmona-Sáez P; Real PJ; Landeira D; Ramos-Mejia V
Cell Death Dis; 2023 Jun; 14(6):357. PubMed ID: 37301844
[TBL] [Abstract] [Full Text] [Related]
3. Pharmacological inhibition of kdm5a for cancer treatment.
Yang GJ; Wu J; Miao L; Zhu MH; Zhou QJ; Lu XJ; Lu JF; Leung CH; Ma DL; Chen J
Eur J Med Chem; 2021 Dec; 226():113855. PubMed ID: 34555614
[TBL] [Abstract] [Full Text] [Related]
4. kdm5a suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2.
Xu S; Wang S; Xing S; Yu D; Rong B; Gao H; Sheng M; Tan Y; Sun X; Wang K; Xue K; Shi Z; Lan F
Blood Adv; 2021 Sep; 5(17):3241-3253. PubMed ID: 34448811
[TBL] [Abstract] [Full Text] [Related]
5. Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of kdm5a at DNA lesions.
Kumbhar R; Sanchez A; Perren J; Gong F; Corujo D; Medina F; Devanathan SK; Xhemalce B; Matouschek A; Buschbeck M; Buck-Koehntop BA; Miller KM
J Cell Biol; 2021 Jul; 220(7):. PubMed ID: 34003252
[TBL] [Abstract] [Full Text] [Related]
6. Clinical impact of genomic characterization of 15 patients with acute megakaryoblastic leukemia-related malignancies.
Lalonde E; Rentas S; Wertheim G; Cao K; Surrey LF; Lin F; Zhao X; Obstfeld A; Aplenc R; Luo M; Li MM
Cold Spring Harb Mol Case Stud; 2021 Apr; 7(2):. PubMed ID: 33832921
[TBL] [Abstract] [Full Text] [Related]
7. CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J; Barbosa IAM; Eder T; Brandstoetter T; Schmidt L; Maurer B; Troester S; Pham HTT; Sagarajit M; Ebner J; Manhart G; Aslan E; Terlecki-Zaniewicz S; Van der Veen C; Hoermann G; Duployez N; Petit A; Lapillonne H; Puissant A; Itzykson R; Moriggl R; Heuser M; Meisel R; Valent P; Sexl V; Zuber J; Grebien F
Blood; 2020 Jul; 136(4):387-400. PubMed ID: 32344427
[TBL] [Abstract] [Full Text] [Related]
8. Human models of NUP98-kdm5a megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities.
Cardin S; Bilodeau M; Roussy M; Aubert L; Milan T; Jouan L; Rouette A; Laramée L; Gendron P; Duchaine J; Decaluwe H; Spinella JF; Mourad S; Couture F; Sinnett D; Haddad É; Landry JR; Ma J; Humphries RK; Roux PP; Hébert J; Gruber TA; Wilhelm BT; Cellot S
Blood Adv; 2019 Nov; 3(21):3307-3321. PubMed ID: 31698461
[TBL] [Abstract] [Full Text] [Related]
9. [Prognostic significance of chimeric fusion gene analysis in pediatric acute megakaryoblastic leukemia].
Tamefusa K; Fukutake K; Ishida H; Tamura A; Endo M; Hamamoto K; Koga Y; Yamada M; Kanamitsu K; Fujiwara K; Washio K; Shimada A
Rinsho Ketsueki; 2019; 60(2):99-105. PubMed ID: 30842387
[TBL] [Abstract] [Full Text] [Related]
10. CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.
Kralickova P; Milota T; Litzman J; Malkusova I; Jilek D; Petanova J; Vydlakova J; Zimulova A; Fronkova E; Svaton M; Kanderova V; Bloomfield M; Parackova Z; Klocperk A; Haviger J; Kalina T; Sediva A
Front Immunol; 2018; 9():3135. PubMed ID: 30723478
[No Abstract] [Full Text] [Related]
11. [Genetic aberrations and new treatment strategies for pediatric acute myeloid leukemia].
Shiba N
Rinsho Ketsueki; 2018; 59(10):2260-2267. PubMed ID: 30305534
[TBL] [Abstract] [Full Text] [Related]
12. NUP98-BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy.
Roussy M; Bilodeau M; Jouan L; Tibout P; Laramée L; Lemyre E; Léveillé F; Tihy F; Cardin S; Sauvageau C; Couture F; Louis I; Choblet A; Patey N; Gendron P; Duval M; Teira P; Hébert J; Wilhelm BT; Choi JK; Gruber TA; Bittencourt H; Cellot S
Genes Chromosomes Cancer; 2018 Jun; 57(6):311-319. PubMed ID: 29427526
[TBL] [Abstract] [Full Text] [Related]
13. Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD; Branstetter C; Ma J; Li Y; Walsh MP; Cheng J; Obulkasim A; Dang J; Easton J; Verboon LJ; Mulder HL; Zimmermann M; Koss C; Gupta P; Edmonson M; Rusch M; Lim JY; Reinhardt K; Pigazzi M; Song G; Yeoh AE; Shih LY; Liang DC; Halene S; Krause DS; Zhang J; Downing JR; Locatelli F; Reinhardt D; van den Heuvel-Eibrink MM; Zwaan CM; Fornerod M; Gruber TA
Nat Genet; 2017 Mar; 49(3):451-456. PubMed ID: 28112737
[TBL] [Abstract] [Full Text] [Related]
14. Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study.
de Rooij JD; Masetti R; van den Heuvel-Eibrink MM; Cayuela JM; Trka J; Reinhardt D; Rasche M; Sonneveld E; Alonzo TA; Fornerod M; Zimmermann M; Pigazzi M; Pieters R; Meshinchi S; Zwaan CM; Locatelli F
Blood; 2016 Jun; 127(26):3424-30. PubMed ID: 27114462
[TBL] [Abstract] [Full Text] [Related]
15. NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.
Gough SM; Lee F; Yang F; Walker RL; Zhu YJ; Pineda M; Onozawa M; Chung YJ; Bilke S; Wagner EK; Denu JM; Ning Y; Xu B; Wang GG; Meltzer PS; Aplan PD
Cancer Discov; 2014 May; 4(5):564-77. PubMed ID: 24535671
[TBL] [Abstract] [Full Text] [Related]
16. NUP98/jarid1a is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern.
de Rooij JD; Hollink IH; Arentsen-Peters ST; van Galen JF; Berna Beverloo H; Baruchel A; Trka J; Reinhardt D; Sonneveld E; Zimmermann M; Alonzo TA; Pieters R; Meshinchi S; van den Heuvel-Eibrink MM; Zwaan CM
Leukemia; 2013 Dec; 27(12):2280-8. PubMed ID: 23531517
[TBL] [Abstract] [Full Text] [Related]
