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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND KDR, VEGFR2, 3791, ENSG00000128052, P35968, VEGFR, CD309, FLK1
324 results:

  • 1. The tyrosine kinase kdr is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein.
    Mohanty S; Suklabaidya S; Lavorgna A; Ueno T; Fujisawa JI; Ngouth N; Jacobson S; Harhaj EW
    Nat Commun; 2024 Jun; 15(1):5380. PubMed ID: 38918393
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Novel guanidine derivatives targeting leukemia as selective Src/Abl dual inhibitors: Design, synthesis and anti-proliferative activity.
    Moustafa AH; AboulMagd AM; Ali AM; Khodairy A; Marzouk AA; Nafady A; T M Nemr M
    Bioorg Chem; 2024 Jun; 147():107410. PubMed ID: 38688197
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Changes in the Concentrations of Proangiogenic Cytokines in Human Brain Glioma and Acute Lymphoblastic leukemia.
    Oldak L; Zielinska Z; Milewska P; Chludzinska-Kasperuk S; Latoch E; Konończuk K; Krawczuk-Rybak M; Starosz A; Grubczak K; Reszeć J; Gorodkiewicz E
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473833
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Exploring Thiazolopyridine AV25R: Unraveling of Biological Activities, Selective Anti-Cancer Properties and In Silico Target and Binding Prediction in Hematological Neoplasms.
    Ladwig A; Gupta S; Ehlers P; Sekora A; Alammar M; Koczan D; Wolkenhauer O; Junghanss C; Langer P; Murua Escobar H
    Molecules; 2023 Dec; 28(24):. PubMed ID: 38138609
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Identification of a Selective FLT3 Inhibitor with Low Activity against vegfr, FGFR, PDGFR, c-KIT, and RET Anti-Targets.
    Akwata D; Kempen AL; Dayal N; Brauer NR; Sintim HO
    ChemMedChem; 2024 Jan; 19(1):e202300442. PubMed ID: 37971283
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Exploration of antiproliferative potential of modified triazole-benzohydrazone scaffold: Multitarget approach.
    Ali AM; Khalaf MA; Bhongade BA; Selim KB; Mostafa AS
    Arch Pharm (Weinheim); 2024 Feb; 357(2):e2300383. PubMed ID: 37946599
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Decoding dysregulated angiogenesis in HTLV-1 asymptomatic carriers compared to healthy individuals.
    Letafati A; Mozhgani SH; Marjani A; Amiri A; Siami Z; Mohammaditabar M; Molaverdi G; Hedayatyaghoobi M
    Med Oncol; 2023 Oct; 40(11):317. PubMed ID: 37792095
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Design, synthesis, and evaluation of new benzimidazole‏ ‏‎thiourea ‎derivatives as antitumor agents.
    Aboutaleb MH; El-Gohary NS; Ghabbour HA; El-Kerdawy MM
    Arch Pharm (Weinheim); 2023 Nov; 356(11):e2300269. PubMed ID: 37602810
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Small molecule protein kinase inhibitors approved by regulatory agencies outside of the United States.
    Roskoski R
    Pharmacol Res; 2023 Aug; 194():106847. PubMed ID: 37454916
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. New antiproliferative 3-substituted oxindoles inhibiting EGFR/vegfr-2 and tubulin polymerization.
    Ezelarab HAA; Ali TFS; Abbas SH; Sayed AM; Beshr EAM; Hassan HA
    Mol Divers; 2024 Apr; 28(2):563-580. PubMed ID: 36790582
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Coumarin derivatives with potential anticancer and antibacterial activity: Design, synthesis, vegfr-2 and DNA gyrase inhibition, and in silico studies.
    Emam SH; Hassan RA; Osman EO; Hamed MIA; Abdou AM; Kandil MM; Elbaz EM; Mikhail DS
    Drug Dev Res; 2023 May; 84(3):433-457. PubMed ID: 36779381
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Focal Segmental Sclerosis Associated with the Novel Multi-tyrosine Kinase Inhibitor Ponatinib.
    Arai H; Yamamoto S; Matsubara T; Miyake T; Tochio A; Mii A; Shimizu A; Minamiguchi S; Muso E; Yanagita M
    Intern Med; 2023 Sep; 62(18):2693-2698. PubMed ID: 36642524
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology.
    Amit M; Xie T; Gleber-Netto FO; Hunt PJ; Mehta GU; Bell D; Silverman DA; Yaman I; Ye Y; Burks JK; Fuller GN; Gidley PW; Nader ME; Raza SM; DeMonte F
    J Exp Clin Cancer Res; 2022 Oct; 41(1):292. PubMed ID: 36195959
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Novel artemisinin derivative FO8643 with anti-angiogenic activity inhibits growth and migration of cancer cells via vegfr2 signaling.
    Lu X; Blatt S; Dawood M; Klauck SM; Fleischer E; Kämmerer PW; Efferth T
    Eur J Pharmacol; 2022 Sep; 930():175158. PubMed ID: 35878807
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib.
    Li A; Ambruso SL; Oto OA; Barry M; Edelstein CL
    BMC Nephrol; 2022 Jul; 23(1):264. PubMed ID: 35870899
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression.
    Porras DP; Reid JC; Tanasijevic B; Golubeva D; Boyd AL; Bhatia M
    Cells; 2022 Jun; 11(12):. PubMed ID: 35741044
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, vegfr-2, and cell cycle of myeloid leukemia.
    Othman EM; Fayed EA; Husseiny EM; Abulkhair HS
    Bioorg Chem; 2022 Oct; 127():105968. PubMed ID: 35728289
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Prophylactic NAC promoted hematopoietic reconstitution by improving endothelial cells after haploidentical HSCT: a phase 3, open-label randomized trial.
    Wang Y; Kong Y; Zhao HY; Zhang YY; Wang YZ; Xu LP; Zhang XH; Liu KY; Huang XJ
    BMC Med; 2022 Apr; 20(1):140. PubMed ID: 35473809
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Differential proteome and functional analysis of NSCLC cell lines in response to Tualang honey treatment.
    Amran N; Abdul-Rahman PS
    J Ethnopharmacol; 2022 Jul; 293():115264. PubMed ID: 35398242
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Neuregulin-1 promotes the proliferation, migration, and angiogenesis of human periodontal ligament stem cells in vitro.
    Li L; Shang L; Kang W; Du L; Ge S
    Cell Biol Int; 2022 May; 46(5):792-805. PubMed ID: 35077607
    [TBL] [Abstract] [Full Text] [Related]  


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