Terms: = Leukemia AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
38 results:
1. Ovatodiolide induces autophagy-mediated cell death through the p62-keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells.
Xia Q; Xie J; Zhang J; Zhang L; Zhou Y; Zhu B; Wu Y; Yang Z; Li J
Chem Biol Interact; 2024 Jan; 387():110819. PubMed ID: 38000454
[TBL] [Abstract] [Full Text] [Related]
2. Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing.
Falchetti M; Delgobo M; Zancanaro H; Almeida K; das Neves RN; Dos Santos B; Stefanes NM; Bishop A; Santos-Silva MC; Zanotto-Filho A
Comput Biol Med; 2023 Jan; 152():106347. PubMed ID: 36493734
[TBL] [Abstract] [Full Text] [Related]
3. Anti-Leukemic Activity of Brassica-Derived Bioactive Compounds in HL-60 Myeloid leukemia Cells.
Núñez-Sánchez MÁ; Martínez-Sánchez MA; Verdejo-Sánchez M; García-Ibáñez P; Oliva Bolarín A; Ramos-Molina B; Moreno DA; Ruiz-Alcaraz AJ
Int J Mol Sci; 2022 Nov; 23(21):. PubMed ID: 36362202
[TBL] [Abstract] [Full Text] [Related]
4. Hydrogen sulfide inhibits human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG4B.
Liu H; Sun J; Cheng X; Duan L; Guo S; Zhang Z; Wan J; Wang C; Zhi X; Yuan L; Wang H
J Med Virol; 2023 Jan; 95(1):e28176. PubMed ID: 36163615
[TBL] [Abstract] [Full Text] [Related]
5. Nestin Regulates keap1-Nrf2-HO-1-Mediated Antioxidant Responses during Stress and Malignant Hematopoiesis.
Lu C; Wei J
Biomed Res Int; 2022; 2022():1706585. PubMed ID: 35669731
[TBL] [Abstract] [Full Text] [Related]
6. The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia.
Niederkorn M; Ishikawa C; M Hueneman K; Bartram J; Stepanchick E; R Bennett J; E Culver-Cochran A; Bolanos LC; Uible E; Choi K; Wunderlich M; Perentesis JP; M Chlon T; Filippi MD; Starczynowski DT
Leukemia; 2022 Feb; 36(2):438-451. PubMed ID: 34465865
[TBL] [Abstract] [Full Text] [Related]
7. SUMO-Modification of Human Nrf2 at K
Walters TS; McIntosh DJ; Ingram SM; Tillery L; Motley ED; Arinze IJ; Misra S
Cell Physiol Biochem; 2021 Mar; 55(2):141-159. PubMed ID: 33770425
[TBL] [Abstract] [Full Text] [Related]
8. Bioinformatic and computational analysis for predominant mutations of the Nrf2/keap1 complex in pediatric leukemia.
Akın-Balı DF; Al-Khafaji K; Aktas SH; Taskin-Tok T
J Biomol Struct Dyn; 2021 Aug; 39(12):4290-4303. PubMed ID: 32469262
[TBL] [Abstract] [Full Text] [Related]
9. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis.
Niederkorn M; Hueneman K; Choi K; Varney ME; Romano L; Pujato MA; Greis KD; Inoue JI; Meetei R; Starczynowski DT
Cell Rep; 2020 Feb; 30(8):2776-2790.e6. PubMed ID: 32101751
[TBL] [Abstract] [Full Text] [Related]
10. Identification of novel Nrf2/keap1 pathway mutations in pediatric acute lymphoblastic leukemia.
Akın-Balı DF; Aktas SH; Unal MA; Kankılıc T
Pediatr Hematol Oncol; 2020 Feb; 37(1):58-75. PubMed ID: 31661353
[TBL] [Abstract] [Full Text] [Related]
11. The Antioxidant from Ethanolic Extract of
Wang KC; Liu YC; El-Shazly M; Shih SP; Du YC; Hsu YM; Lin HY; Chen YC; Wu YC; Yang SC; Lu MC
Int J Mol Sci; 2019 Apr; 20(8):. PubMed ID: 31010164
[No Abstract] [Full Text] [Related]
12. Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity.
Sobh A; Loguinov A; Yazici GN; Zeidan RS; Tagmount A; Hejazi NS; Hubbard AE; Zhang L; Vulpe CD
Toxicol Sci; 2019 May; 169(1):108-121. PubMed ID: 30815697
[TBL] [Abstract] [Full Text] [Related]
13. PML-Nuclear Bodies Regulate the Stability of the Fusion Protein Dendra2-Nrf2 in the Nucleus.
Burroughs AF; Eluhu S; Whalen D; Goodwin JS; Sakwe AM; Arinze IJ
Cell Physiol Biochem; 2018; 47(2):800-816. PubMed ID: 29807365
[TBL] [Abstract] [Full Text] [Related]
14. Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.
Amodio N; Stamato MA; Juli G; Morelli E; Fulciniti M; Manzoni M; Taiana E; Agnelli L; Cantafio MEG; Romeo E; Raimondi L; Caracciolo D; Zuccalà V; Rossi M; Neri A; Munshi NC; Tagliaferri P; Tassone P
Leukemia; 2018 Sep; 32(9):1948-1957. PubMed ID: 29487387
[TBL] [Abstract] [Full Text] [Related]
15. Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein - ring finger protein 4 dependent pathway.
Komaravelli N; Ansar M; Garofalo RP; Casola A
Free Radic Biol Med; 2017 Dec; 113():494-504. PubMed ID: 29107745
[TBL] [Abstract] [Full Text] [Related]
16. Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells.
Rodrigues-Moreira S; Moreno SG; Ghinatti G; Lewandowski D; Hoffschir F; Ferri F; Gallouet AS; Gay D; Motohashi H; Yamamoto M; Joiner MC; Gault N; Romeo PH
Cell Rep; 2017 Sep; 20(13):3199-3211. PubMed ID: 28954235
[TBL] [Abstract] [Full Text] [Related]
17. [Recent advances in elucidating keap1-NRF2 functions in hematopoietic/immune cells and leukemic cells].
Murakami S; Motohashi H
Rinsho Ketsueki; 2016; 57(10):1860-1868. PubMed ID: 27725581
[TBL] [Abstract] [Full Text] [Related]
18. Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells.
Nishimoto S; Suzuki T; Koike S; Yuan B; Takagi N; Ogasawara Y
Toxicol Appl Pharmacol; 2016 Aug; 305():161-168. PubMed ID: 27317373
[TBL] [Abstract] [Full Text] [Related]
19. Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis.
Gonçalves AC; Alves R; Baldeiras I; Cortesão E; Carda JP; Branco CC; Oliveiros B; Loureiro L; Pereira A; Nascimento Costa JM; Sarmento-Ribeiro AB; Mota-Vieira L
Mol Carcinog; 2017 Jan; 56(1):130-148. PubMed ID: 26950655
[TBL] [Abstract] [Full Text] [Related]
20. Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production.
Khan AUH; Rathore MG; Allende-Vega N; Vo DN; Belkhala S; Orecchioni S; Talarico G; Bertolini F; Cartron G; Lecellier CH; Villalba M
EBioMedicine; 2016 Jan; 3():43-53. PubMed ID: 26870816
[TBL] [Abstract] [Full Text] [Related]
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