BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7 AND Clinical Outcome
86 results:

  • 1. Iron overload promotes the progression of mll-AF9 induced acute myeloid leukemia by upregulation of FOS.
    Yang F; Cui X; Wang H; Zhang D; Luo S; Li Y; Dai Y; Yang D; Zhang X; Wang L; Zheng G; Zhang X
    Cancer Lett; 2024 Feb; 583():216652. PubMed ID: 38242196
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
    Liu Y; Klein J; Bajpai R; Dong L; Tran Q; Kolekar P; Smith JL; Ries RE; Huang BJ; Wang YC; Alonzo TA; Tian L; Mulder HL; Shaw TI; Ma J; Walsh MP; Song G; Westover T; Autry RJ; Gout AM; Wheeler DA; Wan S; Wu G; Yang JJ; Evans WE; Loh M; Easton J; Zhang J; Klco JM; Meshinchi S; Brown PA; Pruett-Miller SM; Ma X
    Nat Commun; 2023 Apr; 14(1):1739. PubMed ID: 37019972
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. MicroRNA profiling of paediatric AML with
    Leoncini PP; Vitullo P; Reddel S; Tocco V; Paganelli V; Stocchi F; Mariggiò E; Massa M; Nigita G; Veneziano D; Fadda P; Scarpa M; Pigazzi M; Bertaina A; Rota R; Pagliara D; Merli P
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36321792
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mutational landscape and clinical outcome of pediatric acute myeloid leukemia with 11q23/kmt2a rearrangements.
    Yuen KY; Liu Y; Zhou YZ; Wang Y; Zhou DH; Fang JP; Xu LH
    Cancer Med; 2023 Jan; 12(2):1418-1430. PubMed ID: 35833755
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement.
    Bomken S; Enshaei A; Schwalbe EC; Mikulasova A; Dai Y; Zaka M; Fung KTM; Bashton M; Lim H; Jones L; Karataraki N; Winterman E; Ashby C; Attarbaschi A; Bertrand Y; Bradtke J; Buldini B; Burke GAA; Cazzaniga G; Gohring G; De Groot-Kruseman HA; Haferlach C; Nigro LL; Parihar M; Plesa A; Seaford E; Sonneveld E; Strehl S; Van der Velden VHJ; Rand V; Hunger SP; Harrison CJ; Bacon CM; Van Delft FW; Loh ML; Moppett J; Vormoor J; Walker BA; Moorman AV; Russell LJ
    Haematologica; 2023 Mar; 108(3):717-731. PubMed ID: 35484682
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The Application of Targeted RNA Sequencing for kmt2a-Partial Tandem Duplication Identification and Integrated Analysis of Molecular Characterization in Acute Myeloid leukemia.
    Dai B; Yu H; Ma T; Lei Y; Wang J; Zhang Y; Lu J; Yan H; Jiang L; Chen B
    J Mol Diagn; 2021 Nov; 23(11):1478-1490. PubMed ID: 34384895
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Infantile leukemia-What factors determine its distinct biological nature? Clinicopathological study of 78 cases.
    Liu X; Zhao Y; Luedke C; Jug R; Yang LH; Lu M; Pan Z; Wang D; Lorsbach R; Shi Y; Knez V; Rehder C; Liang X; Wang E
    Int J Lab Hematol; 2021 Oct; 43(5):1117-1122. PubMed ID: 33847065
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Is acute lymphoblastic leukemia with mature B-cell phenotype and
    Hidalgo-Gómez G; Palacio-Garcia C; Gallur L; Blanco A; Tazón-Vega B; Saumell S; Martínez N; Murillo L; Murciano T; Velasco P; Bosch F; Diaz-Heredia C; Ortega M
    Leuk Lymphoma; 2021 Sep; 62(9):2202-2210. PubMed ID: 33827367
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/
    Bill M; Mrózek K; Kohlschmidt J; Eisfeld AK; Walker CJ; Nicolet D; Papaioannou D; Blachly JS; Orwick S; Carroll AJ; Kolitz JE; Powell BL; Stone RM; de la Chapelle A; Byrd JC; Bloomfield CD
    Proc Natl Acad Sci U S A; 2020 Oct; 117(42):26340-26346. PubMed ID: 33020282
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Myeloid sarcoma is associated with poor clinical outcome in pediatric patients with acute myeloid leukemia.
    Xu LH; Wang Y; Chen ZY; Fang JP
    J Cancer Res Clin Oncol; 2020 Apr; 146(4):1011-1020. PubMed ID: 31919567
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Myeloid neoplasms in the setting of sickle cell disease: an intrinsic association with the underlying condition rather than a coincidence; report of 4 cases and review of the literature.
    Li Y; Maule J; Neff JL; McCall CM; Rapisardo S; Lagoo AS; Yang LH; Crawford RD; Zhao Y; Wang E
    Mod Pathol; 2019 Dec; 32(12):1712-1726. PubMed ID: 31371806
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia.
    Mousavian Z; Nowzari-Dalini A; Rahmatallah Y; Masoudi-Nejad A
    Mol Med; 2019 Aug; 25(1):36. PubMed ID: 31370801
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Personalized pharmacokinetic targeting with busulfan in allogeneic hematopoietic stem cell transplantation in infants with acute lymphoblastic leukemia.
    Takachi T; Arakawa Y; Nakamura H; Watanabe T; Aoki Y; Ohshima J; Takahashi Y; Hirayama M; Miyamura T; Sugita K; Koh K; Horibe K; Ishii E; Mizutani S; Tomizawa D
    Int J Hematol; 2019 Sep; 110(3):355-363. PubMed ID: 31201644
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Fulminant blast crisis with de novo 11q23 rearrangement in a Philadelphia-positive CML patient undergoing treatment with dasatinib.
    Janjetovic S; Asemissen AM; Dicker F; Binder M; Dierlamm J; Bokemeyer C; Schafhausen P
    Tumori; 2019 Dec; 105(6):NP8-NP11. PubMed ID: 30935343
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Non-leukemic pediatric mixed phenotype acute leukemia/lymphoma: Genomic characterization and clinical outcome in a prospective trial for pediatric lymphoblastic lymphoma.
    Martin-Guerrero I; Salaverria I; Burkhardt B; Chassagne-Clement C; Szczepanowski M; Bens S; Klapper W; Zimmermann M; Kabickova E; Bertrand Y; Reiter A; Siebert R; Oschlies I
    Genes Chromosomes Cancer; 2019 Jun; 58(6):365-372. PubMed ID: 30578714
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The mll recombinome of acute leukemias in 2017.
    Meyer C; Burmeister T; Gröger D; Tsaur G; Fechina L; Renneville A; Sutton R; Venn NC; Emerenciano M; Pombo-de-Oliveira MS; Barbieri Blunck C; Almeida Lopes B; Zuna J; Trka J; Ballerini P; Lapillonne H; De Braekeleer M; Cazzaniga G; Corral Abascal L; van der Velden VHJ; Delabesse E; Park TS; Oh SH; Silva MLM; Lund-Aho T; Juvonen V; Moore AS; Heidenreich O; Vormoor J; Zerkalenkova E; Olshanskaya Y; Bueno C; Menendez P; Teigler-Schlegel A; Zur Stadt U; Lentes J; Göhring G; Kustanovich A; Aleinikova O; Schäfer BW; Kubetzko S; Madsen HO; Gruhn B; Duarte X; Gameiro P; Lippert E; Bidet A; Cayuela JM; Clappier E; Alonso CN; Zwaan CM; van den Heuvel-Eibrink MM; Izraeli S; Trakhtenbrot L; Archer P; Hancock J; Möricke A; Alten J; Schrappe M; Stanulla M; Strehl S; Attarbaschi A; Dworzak M; Haas OA; Panzer-Grümayer R; Sedék L; Szczepański T; Caye A; Suarez L; Cavé H; Marschalek R
    Leukemia; 2018 Feb; 32(2):273-284. PubMed ID: 28701730
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Transcription control by the ENL YEATS domain in acute leukaemia.
    Erb MA; Scott TG; Li BE; Xie H; Paulk J; Seo HS; Souza A; Roberts JM; Dastjerdi S; Buckley DL; Sanjana NE; Shalem O; Nabet B; Zeid R; Offei-Addo NK; Dhe-Paganon S; Zhang F; Orkin SH; Winter GE; Bradner JE
    Nature; 2017 Mar; 543(7644):270-274. PubMed ID: 28241139
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. MEK inhibition is a promising therapeutic strategy for mll-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations.
    Kerstjens M; Driessen EM; Willekes M; Pinhanços SS; Schneider P; Pieters R; Stam RW
    Oncotarget; 2017 Feb; 8(9):14835-14846. PubMed ID: 27588400
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Prognostic Significance of Mixed-Lineage leukemia (mll) Gene Detected by Real-Time Fluorescence Quantitative PCR Assay in Acute Myeloid leukemia.
    Huang S; Yang H; Li Y; Feng C; Gao L; Chen GF; Gao HH; Huang Z; Li YH; Yu L
    Med Sci Monit; 2016 Aug; 22():3009-17. PubMed ID: 27561414
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis.
    Liu N; Wang C; Wang L; Gao L; Cheng H; Tang G; Hu X; Wang J
    Int J Mol Med; 2016 Jun; 37(6):1686-96. PubMed ID: 27082972
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 5.