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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND KMT2C, ENSG00000055609, MLL3, 58508 AND Treatment
11 results:

  • 1. Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
    Halik A; Tilgner M; Silva P; Estrada N; Altwasser R; Jahn E; Heuser M; Hou HA; Pratcorona M; Hills RK; Metzeler KH; Fenwarth L; Dolnik A; Terre C; Kopp K; Blau O; Szyska M; Christen F; Krönke J; Vasseur L; Löwenberg B; Esteve J; Valk PJM; Duchmann M; Chou WC; Linch DC; Döhner H; Gale RE; Döhner K; Bullinger L; Yoshida K; Damm F
    J Hematol Oncol; 2024 Aug; 17(1):70. PubMed ID: 39160538
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
    Soto-Feliciano YM; Sánchez-Rivera FJ; Perner F; Barrows DW; Kastenhuber ER; Ho YJ; Carroll T; Xiong Y; Anand D; Soshnev AA; Gates L; Beytagh MC; Cheon D; Gu S; Liu XS; Krivtsov AV; Meneses M; de Stanchina E; Stone RM; Armstrong SA; Lowe SW; Allis CD
    Cancer Discov; 2023 Jan; 13(1):146-169. PubMed ID: 36264143
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Advances in the treatment of Hairy Cell leukemia Variant.
    Tran J; Gaulin C; Tallman MS
    Curr Treat Options Oncol; 2022 Jan; 23(1):99-116. PubMed ID: 35178674
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.
    Chen R; Okeyo-Owuor T; Patel RM; Casey EB; Cluster AS; Yang W; Magee JA
    Cell Rep; 2021 Feb; 34(7):108751. PubMed ID: 33596429
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. mll3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway.
    Wu HT; Liu YE; Hsu KW; Wang YF; Chan YC; Chen Y; Chen DR
    Am J Chin Med; 2020; 48(5):1221-1241. PubMed ID: 32668964
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Histone methyltransferases regulate the transcriptional expression of ERα and the proliferation of tamoxifen-resistant breast cancer cells.
    Kim SS; Lee MH; Lee MO
    Breast Cancer Res Treat; 2020 Feb; 180(1):45-54. PubMed ID: 31897900
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. mll3 enhances the transcription of PD-L1 and regulates anti-tumor immunity.
    Xiong W; Deng H; Huang C; Zen C; Jian C; Ye K; Zhong Z; Zhao X; Zhu L
    Biochim Biophys Acta Mol Basis Dis; 2019 Feb; 1865(2):454-463. PubMed ID: 30385408
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients.
    Zhang L; Liu Y; Wang M; Wu Z; Li N; Zhang J; Yang C
    J Mol Cell Biol; 2017 Dec; 9(6):477-488. PubMed ID: 29272522
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.
    Ansari KI; Hussain I; Shrestha B; Kasiri S; Mandal SS
    J Mol Biol; 2011 Aug; 411(2):334-49. PubMed ID: 21683083
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Histone H3K4 trimethylation by mll3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
    Ananthanarayanan M; Li Y; Surapureddi S; Balasubramaniyan N; Ahn J; Goldstein JA; Suchy FJ
    Am J Physiol Gastrointest Liver Physiol; 2011 May; 300(5):G771-81. PubMed ID: 21330447
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.
    Rowley JD; Reshmi S; Sobulo O; Musvee T; Anastasi J; Raimondi S; Schneider NR; Barredo JC; Cantu ES; Schlegelberger B; Behm F; Doggett NA; Borrow J; Zeleznik-Le N
    Blood; 1997 Jul; 90(2):535-41. PubMed ID: 9226152
    [TBL] [Abstract] [Full Text] [Related]  


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