Terms: = Leukemia AND KMT2C, ENSG00000055609, MLL3, 58508 AND Treatment
10 results:
1. A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
Soto-Feliciano YM; Sánchez-Rivera FJ; Perner F; Barrows DW; Kastenhuber ER; Ho YJ; Carroll T; Xiong Y; Anand D; Soshnev AA; Gates L; Beytagh MC; Cheon D; Gu S; Liu XS; Krivtsov AV; Meneses M; de Stanchina E; Stone RM; Armstrong SA; Lowe SW; Allis CD
Cancer Discov; 2023 Jan; 13(1):146-169. PubMed ID: 36264143
[TBL] [Abstract] [Full Text] [Related]
2. Advances in the treatment of Hairy Cell leukemia Variant.
Tran J; Gaulin C; Tallman MS
Curr Treat Options Oncol; 2022 Jan; 23(1):99-116. PubMed ID: 35178674
[TBL] [Abstract] [Full Text] [Related]
3. kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.
Chen R; Okeyo-Owuor T; Patel RM; Casey EB; Cluster AS; Yang W; Magee JA
Cell Rep; 2021 Feb; 34(7):108751. PubMed ID: 33596429
[TBL] [Abstract] [Full Text] [Related]
4. mll3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway.
Wu HT; Liu YE; Hsu KW; Wang YF; Chan YC; Chen Y; Chen DR
Am J Chin Med; 2020; 48(5):1221-1241. PubMed ID: 32668964
[TBL] [Abstract] [Full Text] [Related]
5. Histone methyltransferases regulate the transcriptional expression of ERα and the proliferation of tamoxifen-resistant breast cancer cells.
Kim SS; Lee MH; Lee MO
Breast Cancer Res Treat; 2020 Feb; 180(1):45-54. PubMed ID: 31897900
[TBL] [Abstract] [Full Text] [Related]
6. mll3 enhances the transcription of PD-L1 and regulates anti-tumor immunity.
Xiong W; Deng H; Huang C; Zen C; Jian C; Ye K; Zhong Z; Zhao X; Zhu L
Biochim Biophys Acta Mol Basis Dis; 2019 Feb; 1865(2):454-463. PubMed ID: 30385408
[TBL] [Abstract] [Full Text] [Related]
7. EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients.
Zhang L; Liu Y; Wang M; Wu Z; Li N; Zhang J; Yang C
J Mol Cell Biol; 2017 Dec; 9(6):477-488. PubMed ID: 29272522
[TBL] [Abstract] [Full Text] [Related]
8. HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.
Ansari KI; Hussain I; Shrestha B; Kasiri S; Mandal SS
J Mol Biol; 2011 Aug; 411(2):334-49. PubMed ID: 21683083
[TBL] [Abstract] [Full Text] [Related]
9. Histone H3K4 trimethylation by mll3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
Ananthanarayanan M; Li Y; Surapureddi S; Balasubramaniyan N; Ahn J; Goldstein JA; Suchy FJ
Am J Physiol Gastrointest Liver Physiol; 2011 May; 300(5):G771-81. PubMed ID: 21330447
[TBL] [Abstract] [Full Text] [Related]
10. All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.
Rowley JD; Reshmi S; Sobulo O; Musvee T; Anastasi J; Raimondi S; Schneider NR; Barredo JC; Cantu ES; Schlegelberger B; Behm F; Doggett NA; Borrow J; Zeleznik-Le N
Blood; 1997 Jul; 90(2):535-41. PubMed ID: 9226152
[TBL] [Abstract] [Full Text] [Related]
