Terms: = Leukemia AND LCK, YT16, 3932, P06239, ENSG00000182866, p56lck, pp58lck AND Prognosis
13 results:
1. Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Jin Q; Gutierrez Diaz B; Pieters T; Zhou Y; Narang S; Fijalkwoski I; Borin C; Van Laere J; Payton M; Cho BK; Han C; Sun L; Serafin V; Yacu G; Von Loocke W; Basso G; Veltri G; Dreveny I; Ben-Sahra I; Goo YA; Safgren SL; Tsai YC; Bornhauser B; Suraneni PK; Gaspar-Maia A; Kandela I; Van Vlierberghe P; Crispino JD; Tsirigos A; Ntziachristos P
Sci Adv; 2022 Dec; 8(49):eabq8437. PubMed ID: 36490346
[TBL] [Abstract] [Full Text] [Related]
2. PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120.
Fazio G; Bresolin S; Silvestri D; Quadri M; Saitta C; Vendramini E; Buldini B; Palmi C; Bardini M; Grioni A; Rigamonti S; Galbiati M; Mecca S; Savino AM; Peloso A; Tu JW; Bhatia S; Borkhardt A; Micalizzi C; Lo Nigro L; Locatelli F; Conter V; Rizzari C; Valsecchi MG; Te Kronnie G; Biondi A; Cazzaniga G
EBioMedicine; 2022 Sep; 83():104224. PubMed ID: 35985167
[TBL] [Abstract] [Full Text] [Related]
3. Therapeutic targeting of lck tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.
Laukkanen S; Veloso A; Yan C; Oksa L; Alpert EJ; Do D; Hyvärinen N; McCarthy K; Adhikari A; Yang Q; Iyer S; Garcia SP; Pello A; Ruokoranta T; Moisio S; Adhikari S; Yoder JA; Gallagher K; Whelton L; Allen JR; Jin AH; Loontiens S; Heinäniemi M; Kelliher M; Heckman CA; Lohi O; Langenau DM
Blood; 2022 Oct; 140(17):1891-1906. PubMed ID: 35544598
[TBL] [Abstract] [Full Text] [Related]
4. Dasatinib-therapy induced sustained remission in a child with refractory TCF7-SPI1 T-cell acute lymphoblastic leukemia.
He Y; Zhang J; Zhang Y; Hu Z; Wang P; Gan W; Xie S; Qian M; Pui CH; Jiang H; Zhu X; Zhang H; Zhang W
Pediatr Blood Cancer; 2022 Aug; 69(8):e29724. PubMed ID: 35441457
[TBL] [Abstract] [Full Text] [Related]
5. Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic leukemia.
Braun T; Stachelscheid J; Bley N; Oberbeck S; Otte M; Müller TA; Wahnschaffe L; Glaß M; Ommer K; Franitza M; Gathof B; Altmüller J; Hallek M; Auguin D; Hüttelmaier S; Schrader A; Herling M
Cancer Res; 2022 May; 82(9):1818-1831. PubMed ID: 35259248
[TBL] [Abstract] [Full Text] [Related]
6. Expression and prognosis analyses of CASP1 in acute myeloid leukemia.
Liu J; Zhao M; Feng X; Zeng Y; Lin D
Aging (Albany NY); 2021 May; 13(10):14088-14108. PubMed ID: 33999861
[TBL] [Abstract] [Full Text] [Related]
7. Dasatinib and navitoclax act synergistically to target NUP98-NSD1
Kivioja JL; Thanasopoulou A; Kumar A; Kontro M; Yadav B; Majumder MM; Javarappa KK; Eldfors S; Schwaller J; Porkka K; Heckman CA
Leukemia; 2019 Jun; 33(6):1360-1372. PubMed ID: 30568173
[TBL] [Abstract] [Full Text] [Related]
8. lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome.
Till KJ; Allen JC; Talab F; Lin K; Allsup D; Cawkwell L; Bentley A; Ringshausen I; Duckworth AD; Pettitt AR; Kalakonda N; Slupsky JR
Sci Rep; 2017 Dec; 7(1):16784. PubMed ID: 29196709
[TBL] [Abstract] [Full Text] [Related]
9. Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia.
He BL; Shi X; Man CH; Ma AC; Ekker SC; Chow HC; So CW; Choi WW; Zhang W; Zhang Y; Leung AY
Blood; 2014 Apr; 123(16):2518-29. PubMed ID: 24591202
[TBL] [Abstract] [Full Text] [Related]
10. Main histologic types of non-small-cell lung cancer differ in expression of prognosis-related genes.
Skrzypski M; Dziadziuszko R; Jassem E; Szymanowska-Narloch A; Gulida G; Rzepko R; Biernat W; Taron M; Jelitto-Górska M; Marjański T; Rzyman W; Rosell R; Jassem J
Clin Lung Cancer; 2013 Nov; 14(6):666-673.e2. PubMed ID: 23870818
[TBL] [Abstract] [Full Text] [Related]
11. Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Spijkers-Hagelstein JA; Mimoso Pinhanços S; Schneider P; Pieters R; Stam RW
Leukemia; 2013 Apr; 27(5):1063-71. PubMed ID: 23334362
[TBL] [Abstract] [Full Text] [Related]
12. Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.
Accordi B; Espina V; Giordan M; VanMeter A; Milani G; Galla L; Ruzzene M; Sciro M; Trentin L; De Maria R; te Kronnie G; Petricoin E; Liotta L; Basso G
PLoS One; 2010 Oct; 5(10):e13552. PubMed ID: 21042412
[TBL] [Abstract] [Full Text] [Related]
13. Dasatinib.
Lindauer M; Hochhaus A
Recent Results Cancer Res; 2010; 184():83-102. PubMed ID: 20072833
[TBL] [Abstract] [Full Text] [Related]
