Terms: = Leukemia AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
31 results:
1. Molecular and oral manifestations of langerhans cell histiocytosis preceding acute myeloid leukemia.
Zhang Q; Wu X; Wang X; Pan E; Ying L
BMC Oral Health; 2022 Sep; 22(1):386. PubMed ID: 36064398
[TBL] [Abstract] [Full Text] [Related]
2. Discovery of Covalent mkk4/7 Dual Inhibitor.
Jiang J; Jiang B; He Z; Ficarro SB; Che J; Marto JA; Gao Y; Zhang T; Gray NS
Cell Chem Biol; 2020 Dec; 27(12):1553-1560.e8. PubMed ID: 32916088
[TBL] [Abstract] [Full Text] [Related]
3. Huai Qi Huang-induced Apoptosis via Down-regulating PRKCH and Inhibiting RAF/MEK/ERK Pathway in Ph
Xu WF; Wang ZJ; Li K; Shen YQ; Lu K; Lv XY; Wen YX; Jin RM
Curr Med Sci; 2020 Apr; 40(2):354-362. PubMed ID: 32337697
[TBL] [Abstract] [Full Text] [Related]
4. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Genovese G; Carugo A; Tepper J; Robinson FS; Li L; Svelto M; Nezi L; Corti D; Minelli R; Pettazzoni P; Gutschner T; Wu CC; Seth S; Akdemir KC; Leo E; Amin S; Molin MD; Ying H; Kwong LN; Colla S; Takahashi K; Ghosh P; Giuliani V; Muller F; Dey P; Jiang S; Garvey J; Liu CG; Zhang J; Heffernan TP; Toniatti C; Fleming JB; Goggins MG; Wood LD; Sgambato A; Agaimy A; Maitra A; Roberts CW; Wang H; Viale A; DePinho RA; Draetta GF; Chin L
Nature; 2017 Feb; 542(7641):362-366. PubMed ID: 28178232
[TBL] [Abstract] [Full Text] [Related]
5. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
Jones CL; Gearheart CM; Fosmire S; Delgado-Martin C; Evensen NA; Bride K; Waanders AJ; Pais F; Wang J; Bhatla T; Bitterman DS; de Rijk SR; Bourgeois W; Dandekar S; Park E; Burleson TM; Madhusoodhan PP; Teachey DT; Raetz EA; Hermiston ML; Müschen M; Loh ML; Hunger SP; Zhang J; Garabedian MJ; Porter CC; Carroll WL
Blood; 2015 Nov; 126(19):2202-12. PubMed ID: 26324703
[TBL] [Abstract] [Full Text] [Related]
6. MCL-1 degradation mediated by JNK activation via MEKK1/TAK1-mkk4 contributes to anticancer activity of new tubulin inhibitor MT189.
Wang W; Wang YQ; Meng T; Yi JM; Huan XJ; Ma LP; Tong LJ; Chen Y; Ding J; Shen JK; Miao ZH
Mol Cancer Ther; 2014 Jun; 13(6):1480-91. PubMed ID: 24688049
[TBL] [Abstract] [Full Text] [Related]
7. Functional variant (-1304T>G) in the mkk4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population.
Jiang L; Zhou P; Sun A; Zheng J; Liu B; You Y; Zhang C; Wu D; Zhou Y
Cancer Sci; 2011 Aug; 102(8):1462-8. PubMed ID: 21518142
[TBL] [Abstract] [Full Text] [Related]
8. Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
Mondal S; Mandal C; Sangwan R; Chandra S; Mandal C
Mol Cancer; 2010 Sep; 9():239. PubMed ID: 20836852
[TBL] [Abstract] [Full Text] [Related]
9. The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.
Dai Y; Guzman ML; Chen S; Wang L; Yeung SK; Pei XY; Dent P; Jordan CT; Grant S
Br J Haematol; 2010 Oct; 151(1):70-83. PubMed ID: 20701602
[TBL] [Abstract] [Full Text] [Related]
10. Genetic and molecular alterations in rhabdomyosarcoma: mRNA overexpression of MCL1 and map2k4 genes.
Pazzaglia L; Chiechi A; Conti A; Gamberi G; Magagnoli G; Novello C; Morandi L; Picci P; Mercuri M; Benassi MS
Histol Histopathol; 2009 Jan; 24(1):61-7. PubMed ID: 19012245
[TBL] [Abstract] [Full Text] [Related]
11. Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells.
Hoffman B; Liebermann DA
J Cell Physiol; 2009 Jan; 218(1):26-31. PubMed ID: 18780287
[TBL] [Abstract] [Full Text] [Related]
12. Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
Mann KK; Colombo M; Miller WH
Mol Cancer Ther; 2008 Jun; 7(6):1680-7. PubMed ID: 18566239
[TBL] [Abstract] [Full Text] [Related]
13. Bayesian inference of MicroRNA targets from sequence and expression data.
Huang JC; Morris QD; Frey BJ
J Comput Biol; 2007 Jun; 14(5):550-63. PubMed ID: 17683260
[TBL] [Abstract] [Full Text] [Related]
14. Gadd45 in the response of hematopoietic cells to genotoxic stress.
Liebermann DA; Hoffman B
Blood Cells Mol Dis; 2007; 39(3):329-35. PubMed ID: 17659913
[TBL] [Abstract] [Full Text] [Related]
15. Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products.
Shishodia S; Sethi G; Ahn KS; Aggarwal BB
Biochem Pharmacol; 2007 Jun; 74(1):118-30. PubMed ID: 17475222
[TBL] [Abstract] [Full Text] [Related]
16. Arsenic trioxide inhibits nuclear receptor function via sek1/JNK-mediated RXRalpha phosphorylation.
Mann KK; Padovani AM; Guo Q; Colosimo AL; Lee HY; Kurie JM; Miller WH
J Clin Invest; 2005 Oct; 115(10):2924-33. PubMed ID: 16184197
[TBL] [Abstract] [Full Text] [Related]
17. Antimony trioxide-induced apoptosis is dependent on sek1/JNK signaling.
Mann KK; Davison K; Colombo M; Colosimo AL; Diaz Z; Padovani AM; Guo Q; Scrivens PJ; Gao W; Mader S; Miller WH
Toxicol Lett; 2006 Jan; 160(2):158-70. PubMed ID: 16112521
[TBL] [Abstract] [Full Text] [Related]
18. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of sek1/JNK.
Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
[TBL] [Abstract] [Full Text] [Related]
19. Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.
Shin J; Park B; Cho S; Lee S; Kim Y; Lee SO; Cho K; Lee S; Jin BS; Ahn JH; Choi EJ; Ahn K
J Biol Chem; 2004 Sep; 279(39):40994-1003. PubMed ID: 15273249
[TBL] [Abstract] [Full Text] [Related]
20. Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms.
Dai Y; Rahmani M; Pei XY; Dent P; Grant S
Blood; 2004 Jul; 104(2):509-18. PubMed ID: 15039284
[TBL] [Abstract] [Full Text] [Related]
[Next]
