Terms: = Leukemia AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Diagnosis
26 results:
1.
Aptullahoglu E; Wallis JP; Marr H; Marshall S; Bown N; Willmore E; Lunec J
Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511096
[TBL] [Abstract] [Full Text] [Related]
2. Splicing Modulation Results in Aberrant Isoforms and Protein Products of p53 Pathway Genes and the Sensitization of B Cells to Non-Genotoxic mdm2 Inhibition.
Aptullahoglu E; Ciardullo C; Wallis JP; Marr H; Marshall S; Bown N; Willmore E; Lunec J
Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768733
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3. MN1, FOXP1 and hsa-miR-181a-5p as prognostic markers in acute myeloid leukemia patients treated with intensive induction chemotherapy and autologous stem cell transplantation.
Seipel K; Messerli C; Wiedemann G; Bacher U; Pabst T
Leuk Res; 2020 Feb; 89():106296. PubMed ID: 31927137
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4. Non-genotoxic mdm2 inhibition selectively induces a pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells.
Ciardullo C; Aptullahoglu E; Woodhouse L; Lin WY; Wallis JP; Marr H; Marshall S; Bown N; Willmore E; Lunec J
Haematologica; 2019 Dec; 104(12):2429-2442. PubMed ID: 31004033
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5. P53 protein overexpression in de novo acute myeloid leukemia patients with normal diploid karyotype correlates with FLT3 internal tandem duplication and worse relapse-free survival.
Assi R; Gur HD; Loghavi S; Konoplev SN; Konopleva M; Daver N; Tashakori M; Kadia T; Routbort M; Salem A; Kanagal-Shamanna R; Quesada A; Jabbour EJ; Kornblau SM; Medeiros LJ; Kantarjian H; Khoury JD
Am J Hematol; 2018 Nov; 93(11):1376-1383. PubMed ID: 30117185
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6. Targeting the MTF2-mdm2 Axis Sensitizes Refractory Acute Myeloid leukemia to Chemotherapy.
Maganti HB; Jrade H; Cafariello C; Manias Rothberg JL; Porter CJ; Yockell-Lelièvre J; Battaion HL; Khan ST; Howard JP; Li Y; Grzybowski AT; Sabri E; Ruthenburg AJ; Dilworth FJ; Perkins TJ; Sabloff M; Ito CY; Stanford WL
Cancer Discov; 2018 Nov; 8(11):1376-1389. PubMed ID: 30115703
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7. GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and mdm2.
Han Q; Xu X; Li J; Wang J; Bai L; Wang A; Wang W; Zhang B
Mol Med Rep; 2017 Nov; 16(5):6290-6298. PubMed ID: 28849107
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8. mdm2 promoter polymorphism and p53 codon 72 polymorphism in chronic myeloid leukemia: the association between mdm2 promoter genotype and disease susceptibility, age of onset, and blast-free survival in chronic phase patients receiving imatinib.
Liu YC; Hsiao HH; Yang WC; Liu TC; Chang CS; Yang MY; Lin PM; Hsu JF; Lee CP; Lin SF
Mol Carcinog; 2014 Dec; 53(12):951-9. PubMed ID: 23818300
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9. [The new function of p53 family and its pathway related proteins in female reproduction].
Zhu H; Li A; Yu JH; Xiang CJ; Su SD; Huang L; Fang YJ; Luo Y; Tang WR
Yi Chuan; 2012 Aug; 34(8):943-9. PubMed ID: 22917899
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10. Pharmacological activation of the p53 pathway in haematological malignancies.
Saha MN; Micallef J; Qiu L; Chang H
J Clin Pathol; 2010 Mar; 63(3):204-9. PubMed ID: 19955555
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11. Frequency and prognostic significance of murine double minute protein-2 overexpression and p53 gene mutations in childhood acute lymphoblastic leukemia.
Hendy OM; Elghannam DM; El-Sharnouby JA; Goda EF; El-Ashry R; Al-Tonbary Y
Hematology; 2009 Dec; 14(6):335-40. PubMed ID: 19941740
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12. TP53 R72P and mdm2 SNP309 polymorphisms in modification of childhood acute lymphoblastic leukemia susceptibility.
Do TN; Ucisik-Akkaya E; Davis CF; Morrison BA; Dorak MT
Cancer Genet Cytogenet; 2009 Nov; 195(1):31-6. PubMed ID: 19837266
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13. Epigenetic dysregulation of the DAP kinase/p14/hdm2/p53/Apaf-1 apoptosis pathway in acute leukaemias.
Chim CS; Chan WW; Kwong YL
J Clin Pathol; 2008 Jul; 61(7):844-7. PubMed ID: 18587015
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14. Prevalence and prognostic significance of murine double minute protein-2 overexpression and P53 gene mutations in childhood acute lymphoblastic leukemia.
Hendy OM; Elghannam DM; El-Sharnouby JA; Goda EF; El-Ashry R; Al-Tonbary Y
Egypt J Immunol; 2008; 15(1):93-100. PubMed ID: 20306673
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15. p53 pathway gene single nucleotide polymorphisms and chronic lymphocytic leukemia.
Lahiri O; Harris S; Packham G; Howell M
Cancer Genet Cytogenet; 2007 Nov; 179(1):36-44. PubMed ID: 17981213
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16. HDM4 (hdmx) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target.
Han X; Garcia-Manero G; McDonnell TJ; Lozano G; Medeiros LJ; Xiao L; Rosner G; Nguyen M; Fernandez M; Valentin-Vega YA; Barboza J; Jones DM; Rassidakis GZ; Kantarjian HM; Bueso-Ramos CE
Mod Pathol; 2007 Jan; 20(1):54-62. PubMed ID: 17143258
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17. Frequent DAP kinase but not p14 or Apaf-1 hypermethylation in B-cell chronic lymphocytic leukemia.
Chim CS; Fung TK; Wong KF; Lau JS; Liang R
J Hum Genet; 2006; 51(9):832-838. PubMed ID: 16897188
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18. A limited role for TP53 mutation in the transformation of follicular lymphoma to diffuse large B-cell lymphoma.
Davies AJ; Lee AM; Taylor C; Clear AJ; Goff LK; Iqbal S; Cuthbert-Heavens D; Calaminici M; Norton AJ; Lister TA; Fitzgibbon J
Leukemia; 2005 Aug; 19(8):1459-65. PubMed ID: 15902285
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19. Altered expression of p53 and mdm2 proteins in hematological malignancies.
Koníková E; Kusenda J
Neoplasma; 2003; 50(1):31-40. PubMed ID: 12687276
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20. High Bad and Bax mRNA expression correlate with negative outcome in acute myeloid leukemia (AML).
Köhler T; Schill C; Deininger MW; Krahl R; Borchert S; Hasenclever D; Leiblein S; Wagner O; Niederwieser D
Leukemia; 2002 Jan; 16(1):22-9. PubMed ID: 11840259
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