Terms: = Leukemia AND MLLT11, Q13015, 10962, ENSG00000213190, AF1Q
29 results:
1. Cerebellar granule cell migration and folia development require mllt11/af1q/Tcf7c.
Blommers M; Stanton-Turcotte D; Witt EA; Heidari M; Iulianella A
Dev Neurobiol; 2024 Apr; 84(2):74-92. PubMed ID: 38509451
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2. af1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis.
Oskouian B; Lee JY; Asgharzadeh S; Khan R; Zhang M; Weisbrod JR; Choi YJ; Puri L; Aguilar AE; Zhao P; Saba JD
Oncogene; 2024 Apr; 43(16):1203-1213. PubMed ID: 38413795
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3. A Phase II Trial of Imatinib Mesylate as Maintenance Therapy for Patients With Newly Diagnosed C-kit-positive Acute Myeloid leukemia.
Advani AS; Tse W; Li H; Jia X; Elson P; Cooper B; Ali-Osman F; Park J; Rao AV; Rizzieri DA; Wang ES; Cotta CV; Kalaycio M; Sobecks RM; Rouphail B; Maciejewski JP; Fensterl J; Carew JS; Foster B; Rush ML; Tripp B; Adams D; Corrigan D; Griffiths EA; Sekeres MA
Clin Lymphoma Myeloma Leuk; 2021 Feb; 21(2):113-118. PubMed ID: 33422470
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4. Panoramic view of common fusion genes in a large cohort of Chinese de novo acute myeloid leukemia patients.
Chen X; Wang F; Zhang Y; Wang M; Tian W; Teng W; Ma X; Guo L; Fang J; Zhang Y; Zhu P; Liu H
Leuk Lymphoma; 2019 Apr; 60(4):1071-1078. PubMed ID: 30277115
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5. Novel af1q/mllt11 favorably affects imatinib resistance and cell survival in chronic myeloid leukemia.
Li W; Ji M; Lu F; Pang Y; Dong X; Zhang J; Li P; Ye J; Zang S; Ma D; Ji C
Cell Death Dis; 2018 Aug; 9(9):855. PubMed ID: 30154435
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6. The incidence and distribution characteristics of MLL rearrangements in Chinese acute myeloid leukemia patients by multiplex nested RT-PCR.
Yang H; Cao T; Gao L; Wang L; Zhu C; Xu Y; Jing Y; Zhu H; Lv N; Yu L
Technol Health Care; 2017 Jul; 25(S1):259. PubMed ID: 28582914
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7. Involvement of af1q/mllt11 in the progression of ovarian cancer.
Tiberio P; Lozneanu L; Angeloni V; Cavadini E; Pinciroli P; Callari M; Carcangiu ML; Lorusso D; Raspagliesi F; Pala V; Daidone MG; Appierto V
Oncotarget; 2017 Apr; 8(14):23246-23264. PubMed ID: 28423573
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8. Acute Myeloid leukemia (AML): Upregulation of BAALC/MN1/mllt11/EVI1 Gene Cluster Relate With Poor Overall Survival and a Possible Linkage With Coexpression of MYC/BCL2 Proteins.
Akhter A; Farooq F; Elyamany G; Mughal MK; Rashid-Kolvear F; Shabani-Rad MT; Street L; Mansoor A
Appl Immunohistochem Mol Morphol; 2018 Aug; 26(7):483-488. PubMed ID: 28362701
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9. Activation of Wnt signaling pathway by af1q enriches stem-like population and enhance mammosphere formation of breast cells.
Tse CO; Kim S; Park J
Biochem Biophys Res Commun; 2017 Mar; 484(4):884-889. PubMed ID: 28188793
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10. Molecular characterization of KMT2A fusion partner genes in 13 cases of pediatric leukemia with complex or cryptic karyotypes.
Ney Garcia DR; de Souza MT; de Figueiredo AF; Othman MAK; Rittscher K; Abdelhay E; Capela de Matos RR; Meyer C; Marschalek R; Land MGP; Liehr T; Ribeiro RC; Silva MLM
Hematol Oncol; 2017 Dec; 35(4):760-768. PubMed ID: 27282883
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11. af1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.
Park J; Schlederer M; Schreiber M; Ice R; Merkel O; Bilban M; Hofbauer S; Kim S; Addison J; Zou J; Ji C; Bunting ST; Wang Z; Shoham M; Huang G; Bago-Horvath Z; Gibson LF; Rojanasakul Y; Remick S; Ivanov A; Pugacheva E; Bunting KD; Moriggl R; Kenner L; Tse W
Oncotarget; 2015 Aug; 6(24):20697-710. PubMed ID: 26079538
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12. Degradation of af1q by chaperone-mediated autophagy.
Li P; Ji M; Lu F; Zhang J; Li H; Cui T; Li Wang X; Tang D; Ji C
Exp Cell Res; 2014 Sep; 327(1):48-56. PubMed ID: 24880125
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13. Molecular identification of a new splicing variant of the MLL - mllt11 fusion transcript in an adult with acute myeloid leukemia and t(1;11)(q21;q23).
Lee SG; Park TS; Yang JJ; Oh SH; Cho EH; Lee S; Oh D; Huh JY; Marschalek R; Meyer C
Acta Haematol; 2012; 128(3):131-8. PubMed ID: 22854283
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14. Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution.
Cerveira N; Lisboa S; Correia C; Bizarro S; Santos J; Torres L; Vieira J; Barros-Silva JD; Pereira D; Moreira C; Meyer C; Oliva T; Moreira I; Martins Â; Viterbo L; Costa V; Marschalek R; Pinto A; Mariz JM; Teixeira MR
Mol Oncol; 2012 Oct; 6(5):553-64. PubMed ID: 22846743
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15. A three-way translocation of MLL, mllt11, and the novel reciprocal partner gene MYO18A in a child with acute myeloid leukemia.
Ussowicz M; Jaśkowiec A; Meyer C; Marschalek R; Chybicka A; Szczepański T; Haus O
Cancer Genet; 2012 May; 205(5):261-5. PubMed ID: 22682626
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16. MIR29B regulates expression of mllt11 (af1q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML.
Xiong Y; Li Z; Ji M; Tan AC; Bemis J; Tse JV; Huang G; Park J; Ji C; Chen J; Bemis LT; Bunting KD; Tse W
Br J Haematol; 2011 Jun; 153(6):753-7. PubMed ID: 21496004
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17. ETV6-ARNT fusion in a patient with childhood T lymphoblastic leukemia.
Otsubo K; Kanegane H; Eguchi M; Eguchi-Ishimae M; Tamura K; Nomura K; Abe A; Ishii E; Miyawaki T
Cancer Genet Cytogenet; 2010 Oct; 202(1):22-6. PubMed ID: 20804916
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18. Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics.
Gregory TK; Wald D; Chen Y; Vermaat JM; Xiong Y; Tse W
J Hematol Oncol; 2009 Jun; 2():23. PubMed ID: 19490647
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19. Elevated af1q expression is a poor prognostic marker for adult acute myeloid leukemia patients with normal cytogenetics.
Strunk CJ; Platzbecker U; Thiede C; Schaich M; Illmer T; Kang Z; Leahy P; Li C; Xie X; Laughlin MJ; Lazarus HM; Gerson SL; Bunting KD; Ehninger G; Tse W
Am J Hematol; 2009 May; 84(5):308-9. PubMed ID: 19396856
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20. Oncogene af1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway.
Co NN; Tsang WP; Wong TW; Cheung HH; Tsang TY; Kong SK; Kwok TT
Mol Cancer Ther; 2008 Oct; 7(10):3160-8. PubMed ID: 18852119
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