Terms: = Leukemia AND MLLT3, AF9, 4300, ENSG00000171843, P42568, YEATS3, AF-9 AND Treatment
144 results:
1. Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-af9 leukemia.
Li Y; Seet CS; Mack R; Joshi K; Runde AP; Hagen PA; Barton K; Breslin P; Kini A; Ji HL; Zhang J
Stem Cell Reports; 2024 Jan; 19(1):100-111. PubMed ID: 38101400
[TBL] [Abstract] [Full Text] [Related]
2. Transformation from acute promyelocytic leukemia in pregnancy to acute myeloid leukemia with MLL-af9 fusion gene: A case report and literature review.
Gao Y; Han N; Jiang Y; Lu Z
Medicine (Baltimore); 2023 Dec; 102(48):e36403. PubMed ID: 38050244
[TBL] [Abstract] [Full Text] [Related]
3. Uncovering NOTCH1 as a Promising Target in the treatment of
Fischer J; Erkner E; Fitzel R; Radszuweit P; Keppeler H; Korkmaz F; Roti G; Lengerke C; Schneidawind D; Schneidawind C
Int J Mol Sci; 2023 Sep; 24(19):. PubMed ID: 37833915
[No Abstract] [Full Text] [Related]
4. Droplet Digital PCR for Oncogenic KMT2A Fusion Detection.
Young AL; Davis HC; Challen GA
J Mol Diagn; 2023 Dec; 25(12):898-906. PubMed ID: 37813299
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5. Distinct and targetable role of calcium-sensing receptor in leukaemia.
Pereira RS; Kumar R; Cais A; Paulini L; Kahler A; Bravo J; Minciacchi VR; Krack T; Kowarz E; Zanetti C; Godavarthy PS; Hoeller F; Llavona P; Stark T; Tascher G; Nowak D; Meduri E; Huntly BJP; Münch C; Pampaloni F; Marschalek R; Krause DS
Nat Commun; 2023 Oct; 14(1):6242. PubMed ID: 37802982
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6. Interleukin-6 Facilitates Acute Myeloid leukemia Chemoresistance via Mitofusin 1-Mediated Mitochondrial Fusion.
Hou D; Zheng X; Cai D; You R; Liu J; Wang X; Liao X; Tan M; Lin L; Wang J; Zhang S; Huang H
Mol Cancer Res; 2023 Dec; 21(12):1366-1378. PubMed ID: 37698549
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7. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
Liu Y; Klein J; Bajpai R; Dong L; Tran Q; Kolekar P; Smith JL; Ries RE; Huang BJ; Wang YC; Alonzo TA; Tian L; Mulder HL; Shaw TI; Ma J; Walsh MP; Song G; Westover T; Autry RJ; Gout AM; Wheeler DA; Wan S; Wu G; Yang JJ; Evans WE; Loh M; Easton J; Zhang J; Klco JM; Meshinchi S; Brown PA; Pruett-Miller SM; Ma X
Nat Commun; 2023 Apr; 14(1):1739. PubMed ID: 37019972
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8. Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation.
Lu Y; Yang L; Shen M; Zhang Z; Wang S; Chen F; Chen N; Xu Y; Zeng H; Chen M; Chen S; Wang F; Hu M; Wang J
Leukemia; 2023 May; 37(5):1039-1047. PubMed ID: 36997676
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9. De novo myeloid sarcoma mimicking gynecological tumors: a retrospective case series of eight patients.
Gu Y; Zheng H; Mo S; Guo T; Chen L; Yang J; Xiang Y
BMC Womens Health; 2023 Mar; 23(1):141. PubMed ID: 36978050
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10. Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.
Casado P; Rio-Machin A; Miettinen JJ; Bewicke-Copley F; Rouault-Pierre K; Krizsan S; Parsons A; Rajeeve V; Miraki-Moud F; Taussig DC; Bödör C; Gribben J; Heckman C; Fitzgibbon J; Cutillas PR
Signal Transduct Target Ther; 2023 Feb; 8(1):80. PubMed ID: 36843114
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11. Comprehensive molecular understanding of pediatric acute myeloid leukemia.
Shiba N
Int J Hematol; 2023 Feb; 117(2):173-181. PubMed ID: 36653696
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12. An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene.
Jurutka PW; di Martino O; Reshi S; Mallick S; Sausedo MA; Moen GA; Lee IJ; Ivan DJ; Krall TD; Peoples SJ; Perez A; Tromba L; Le A; Khadka I; Petros R; Savage BM; Salama E; Salama J; Ziller JW; Noh Y; Lee MY; Liu W; Welch JS; Marshall PA; Wagner CE
Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555852
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13. Lineage switch in a pediatric patient with KMT2A-mllt3 from acute megakaryoblastic leukemia to T cell acute lymphoblastic leukemia at the fourth relapse after allo-HSCT: with literature review.
Gao L; Lu J; Li J; Hu Y; Lu Y; Du W; Hu S
Int J Hematol; 2023 May; 117(5):781-785. PubMed ID: 36472792
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14. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia.
Liu X; Sato N; Yabushita T; Li J; Jia Y; Tamura M; Asada S; Fujino T; Fukushima T; Yonezawa T; Tanaka Y; Fukuyama T; Tsuchiya A; Shikata S; Iwamura H; Kinouchi C; Komatsu K; Yamasaki S; Shibata T; Sasaki AT; Schibler J; Wunderlich M; O'Brien E; Mizukawa B; Mulloy JC; Sugiura Y; Takizawa H; Shibata T; Miyake K; Kitamura T; Goyama S
EMBO Mol Med; 2023 Jan; 15(1):e15631. PubMed ID: 36453131
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15. Pharmacological targeting of type phosphodiesterase 4 inhibits the development of acute myeloid leukemia by impairing mitochondrial function through the Wnt/β-catenin pathway.
Mao P; Huang C; Li Y; Zhao Y; Zhou S; Zhao Z; Mu Y; Wang L; Li F; Zhao AZ
Biomed Pharmacother; 2023 Jan; 157():114027. PubMed ID: 36436494
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16. Poor treatment responses were related to poor outcomes in pediatric B cell acute lymphoblastic leukemia with KMT2A rearrangements.
Wen J; Zhou M; Shen Y; Long Y; Guo Y; Song L; Xiao J
BMC Cancer; 2022 Aug; 22(1):859. PubMed ID: 35933338
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17. Fusion transcript analysis reveals slower response kinetics than multiparameter flow cytometry in childhood acute myeloid leukaemia.
Karlsson L; Nyvold CG; Soboli A; Johansson P; Palmqvist L; Tierens A; Hasle H; Lausen B; Jónsson ÓG; Jürgensen GW; Ebbesen LH; Abrahamsson J; Fogelstrand L
Int J Lab Hematol; 2022 Dec; 44(6):1094-1101. PubMed ID: 35918824
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18. KDM4 inhibitor SD49-7 attenuates leukemia stem cell
Li Y; Wang C; Gao H; Gu J; Zhang Y; Zhang Y; Xie M; Cheng X; Yang M; Zhang W; Li Y; He M; Xu H; Zhang H; Ji Q; Ma T; Ding S; Zhao Y; Gao Y
Theranostics; 2022; 12(11):4922-4934. PubMed ID: 35836814
[No Abstract] [Full Text] [Related]
19. A Novel BRD Family PROTAC Inhibitor dBET1 Exerts Great Anti-Cancer Effects by Targeting c-MYC in Acute Myeloid leukemia Cells.
Zhang K; Gao L; Wang J; Chu X; Zhang Z; Zhang Y; Fang F; Tao Y; Li X; Tian Y; Li Z; Sang X; Ma L; Lu L; Chen Y; Yu J; Zhuo R; Wu S; Pan J; Hu S
Pathol Oncol Res; 2022; 28():1610447. PubMed ID: 35832114
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20. Design, Synthesis, and Biological Evaluations of DOT1L Peptide Mimetics Targeting the Protein-Protein Interactions between DOT1L and MLL-af9/MLL-ENL.
Yuan Y; Du L; Tan R; Yu Y; Jiang J; Yao A; Luo J; Tang R; Xiao Y; Sun H
J Med Chem; 2022 Jun; 65(11):7770-7785. PubMed ID: 35612819
[TBL] [Abstract] [Full Text] [Related]
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