Terms: = Leukemia AND MSI2, ENSG00000153944, 124540
49 results:
1. Clonal evolution dissection reveals that a high msi2 level promotes chemoresistance in T-cell acute lymphoblastic leukemia.
Zhang J; Duan Y; Wu P; Chang Y; Wang Y; Hu T; Liu C; Chen X; Zong S; Chen X; Wu Y; Jin L; Lan Y; Liu X; Cheng X; Ding F; Li T; Chen X; Guo Y; Chen Y; Yang W; Zhang L; Zou Y; Cheng T; Zhu X; Zhang Y
Blood; 2024 Jan; 143(4):320-335. PubMed ID: 37801708
[TBL] [Abstract] [Full Text] [Related]
2. Down-regulation of Musashi-2 exerts antileukemic effects on acute lymphoblastic leukemia cells and increases sensitivity to dexamethasone.
Zou D; Lv M; Chen Y; Niu T; Ma C; Shi C; Huang Z; Wu Y; Yang S; Wang Y; Wu N; Zhang Y; Ouyang G; Mu Q
Ann Hematol; 2024 Jan; 103(1):141-151. PubMed ID: 37749318
[TBL] [Abstract] [Full Text] [Related]
3. Transcriptome sequencing identifies novel EVX fusions involved in transcriptional activation of HOX family genes in pediatric immature T-cell acute lymphoblastic leukemia: two cases reports and a literature review.
Zhang X; Cui B; Li Y; Li Z; Zheng J; Chu X; Xiao P; Lu J; Wang Z; Cen J; Liu Y; Hu S
Int J Hematol; 2023 Oct; 118(4):508-513. PubMed ID: 37243888
[TBL] [Abstract] [Full Text] [Related]
4. MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia.
Li F; Han Y; Chen R; Jiang Y; Chen C; Wang X; Zhou J; Xu Q; Jiang S; Zhang S; Yu K; Zhang S
J Transl Med; 2023 May; 21(1):309. PubMed ID: 37149661
[TBL] [Abstract] [Full Text] [Related]
5. Competitive evolved sub-clonal BCR::ABL1 and novel msi2::PC fusion genes in myelodysplastic syndrome with isolated del(5q).
Zhang Y; Liu Y; Wang T; Wang H; Chen X; Cao P; Ma X; Liu M; Xu P; Bi H; Pan J; Jiang Y; Li X; Wang W; Liu H
Hematol Oncol; 2023 Feb; 41(1):178-181. PubMed ID: 36301018
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6.
Liu M; Du M; Yu J; Qian Z; Gao Y; Pan W; Zhao X; Wang M; Li H; Zheng J; Huang Q; Wang LM; Xiao H
Oncoimmunology; 2022; 11(1):2016158. PubMed ID: 35003895
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7. Distinct noncoding RNAs and RNA binding proteins associated with high-risk pediatric and adult acute myeloid leukemias detected by regulatory network analysis.
Liu Z; Spiegelman VS; Wang HG
Cancer Rep (Hoboken); 2022 Oct; 5(10):e1592. PubMed ID: 34862757
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8. Identification of gene targets of mutant C/EBPα reveals a critical role for msi2 in CEBPA-mutated AML.
Heyes E; Schmidt L; Manhart G; Eder T; Proietti L; Grebien F
Leukemia; 2021 Sep; 35(9):2526-2538. PubMed ID: 33623142
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9. Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target.
Palacios F; Yan XJ; Ferrer G; Chen SS; Vergani S; Yang X; Gardner J; Barrientos JC; Rock P; Burack R; Kolitz JE; Allen SL; Kharas MG; Abdel-Wahab O; Rai KR; Chiorazzi N
Leukemia; 2021 Apr; 35(4):1037-1052. PubMed ID: 33504942
[TBL] [Abstract] [Full Text] [Related]
10. A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.
Spinler K; Bajaj J; Ito T; Zimdahl B; Hamilton M; Ahmadi A; Koechlein CS; Lytle N; Kwon HY; Anower-E-Khuda F; Sun H; Blevins A; Weeks J; Kritzik M; Karlseder J; Ginsberg MH; Park PW; Esko JD; Reya T
Nat Commun; 2020 Nov; 11(1):5998. PubMed ID: 33243988
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11. Unravelling the drugability of msi2 RNA recognition motif (RRM) protein and the prediction of their effective antileukemia inhibitors from traditional herb concoctions.
Adeniyi JN; Adeniyi AA; Moodley R; Nlooto M; Ngcobo M; Gomo E; Conradie J
J Biomol Struct Dyn; 2022 Apr; 40(6):2516-2529. PubMed ID: 33131412
[TBL] [Abstract] [Full Text] [Related]
12. RNA-Binding Proteins in Acute leukemias.
Schuschel K; Helwig M; Hüttelmaier S; Heckl D; Klusmann JH; Hoell JI
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32408494
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13. HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells.
Nguyen DTT; Lu Y; Chu KL; Yang X; Park SM; Choo ZN; Chin CR; Prieto C; Schurer A; Barin E; Savino AM; Gourkanti S; Patel P; Vu LP; Leslie CS; Kharas MG
Nat Commun; 2020 Apr; 11(1):2026. PubMed ID: 32332729
[TBL] [Abstract] [Full Text] [Related]
14. Suppression of Musashi‑2 by the small compound largazole exerts inhibitory effects on malignant cells.
Wang M; Sun XY; Zhou YC; Zhang KJ; Lu YZ; Liu J; Huang YC; Wang GZ; Jiang S; Zhou GB
Int J Oncol; 2020 May; 56(5):1274-1283. PubMed ID: 32319553
[TBL] [Abstract] [Full Text] [Related]
15. Knockdown of Musashi RNA Binding Proteins Decreases Radioresistance but Enhances Cell Motility and Invasion in Triple-Negative Breast Cancer.
Troschel FM; Minte A; Ismail YM; Kamal A; Abdullah MS; Ahmed SH; Deffner M; Kemper B; Kiesel L; Eich HT; Ibrahim SA; Götte M; Greve B
Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32245259
[TBL] [Abstract] [Full Text] [Related]
16. Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Minuesa G; Albanese SK; Xie W; Kazansky Y; Worroll D; Chow A; Schurer A; Park SM; Rotsides CZ; Taggart J; Rizzi A; Naden LN; Chou T; Gourkanti S; Cappel D; Passarelli MC; Fairchild L; Adura C; Glickman JF; Schulman J; Famulare C; Patel M; Eibl JK; Ross GM; Bhattacharya S; Tan DS; Leslie CS; Beuming T; Patel DJ; Goldgur Y; Chodera JD; Kharas MG
Nat Commun; 2019 Jun; 10(1):2691. PubMed ID: 31217428
[TBL] [Abstract] [Full Text] [Related]
17. PTBP2 exon 10 inclusion is associated with the progression of CML and it is BCR-ABL1 dependent.
Nandagopalan SR; Agatheeswaran S; Vadlamudi Y; Biswas S; Biswas G; Pattnayak NC; Chakraborty S
Int J Biochem Cell Biol; 2019 Apr; 109():69-75. PubMed ID: 30726713
[TBL] [Abstract] [Full Text] [Related]
18. Transcriptome-wide analysis uncovers the targets of the RNA-binding protein msi2 and effects of msi2's RNA-binding activity on IL-6 signaling.
Duggimpudi S; Kloetgen A; Maney SK; Münch PC; Hezaveh K; Shaykhalishahi H; Hoyer W; McHardy AC; Lang PA; Borkhardt A; Hoell JI
J Biol Chem; 2018 Oct; 293(40):15359-15369. PubMed ID: 30126842
[TBL] [Abstract] [Full Text] [Related]
19. PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells.
Belew MS; Bhatia S; Keyvani Chahi A; Rentas S; Draper JS; Hope KJ
Stem Cell Reports; 2018 Apr; 10(4):1384-1397. PubMed ID: 29641991
[TBL] [Abstract] [Full Text] [Related]
20. Stem Cells, Cancer, and MUSASHI in Blood and Guts.
Kharas MG; Lengner CJ
Trends Cancer; 2017 May; 3(5):347-356. PubMed ID: 28718412
[TBL] [Abstract] [Full Text] [Related]
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