Terms: = Leukemia AND MTOR, FRAP2, FRAP1, 2475, ENSG00000198793, P42345, RAPT1, RAFT1, FRAP, FLJ44809 AND Prognosis
109 results:
1. Inhibition of PI3K-AKT-mtor pathway and modulation of histone deacetylase enzymes reduce the growth of acute myeloid leukemia cells.
Şansaçar M; Sağır H; Gencer Akçok EB
Med Oncol; 2023 Dec; 41(1):31. PubMed ID: 38148433
[TBL] [Abstract] [Full Text] [Related]
2. The LIFR Inhibitor EC359 Effectively Targets Type II Endometrial Cancer by Blocking LIF/LIFR Oncogenic Signaling.
Spencer N; Rodriguez Sanchez AL; Gopalam R; Subbarayalu P; Medina DM; Yang X; Ramirez P; Randolph L; Aller EJ; Santhamma B; Rao MK; Tekmal RR; Nair HB; Kost ER; Vadlamudi RK; Viswanadhapalli S
Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139260
[TBL] [Abstract] [Full Text] [Related]
3. XBP1 promotes NRAS
Salimi A; Schemionek-Reinders M; Huber M; Vieri M; Patterson JB; Alten J; Brümmendorf TH; Kharabi Masouleh B; Appelmann I
J Cell Mol Med; 2023 Nov; 27(21):3363-3377. PubMed ID: 37753803
[TBL] [Abstract] [Full Text] [Related]
4. PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia.
Carlock C; Bai Y; Paige-Hood A; Li Q; Nguele Meke F; Zhang ZY
JCI Insight; 2023 Oct; 8(19):. PubMed ID: 37665633
[TBL] [Abstract] [Full Text] [Related]
5. SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses leukemia Growth in a T-ALL Xenotransplantation Mouse Model.
Ehm P; Rietow R; Wegner W; Bußmann L; Kriegs M; Dierck K; Horn S; Streichert T; Horstmann M; Jücker M
Cells; 2023 Jul; 12(13):. PubMed ID: 37443832
[TBL] [Abstract] [Full Text] [Related]
6. Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia.
Villa-Morales M; Pérez-Gómez L; Pérez-Gómez E; López-Nieva P; Fernández-Navarro P; Santos J
Int J Mol Sci; 2023 Jun; 24(12):. PubMed ID: 37373496
[TBL] [Abstract] [Full Text] [Related]
7. ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to FGFR1 inhibitors through amino acid metabolic reprogramming.
Zhang ZJ; Wu QF; Ren AQ; Chen Q; Shi JZ; Li JP; Liu XY; Zhang ZJ; Tang YZ; Zhao Y; Yao NN; Zhang XY; Liu CP; Dong G; Zhao JX; Xu MJ; Yue YQ; Hu J; Sun F; Liu Y; Ao QL; Zhou FL; Wu H; Zhang TC; Zhu HC
Acta Pharmacol Sin; 2023 Nov; 44(11):2282-2295. PubMed ID: 37280363
[TBL] [Abstract] [Full Text] [Related]
8. Improved efficacy of quizartinib in combination therapy with PI3K inhibition in primary FLT3-ITD AML cells.
Darici S; Jørgensen HG; Huang X; Serafin V; Antolini L; Barozzi P; Luppi M; Forghieri F; Marmiroli S; Zavatti M
Adv Biol Regul; 2023 Aug; 89():100974. PubMed ID: 37245251
[TBL] [Abstract] [Full Text] [Related]
9. Dvl proteins regulate SMAD1, AHR, mtor, BRD7 protein expression while differentially regulating canonical and non-canonical Wnt signaling pathways in CML cell lines.
Caliskan C; Yuce Z; Ogun Sercan H
Gene; 2023 Feb; 854():147109. PubMed ID: 36509295
[TBL] [Abstract] [Full Text] [Related]
10. Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia.
Chiriches C; Khan D; Wieske M; Guillen N; Rokicki M; Guy C; Wilson M; Heesom KJ; Ottmann OG; Ruthardt M
Ann Hematol; 2022 Oct; 101(10):2179-2193. PubMed ID: 35941390
[TBL] [Abstract] [Full Text] [Related]
11. RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.
Pham LT; Peng H; Ueno M; Kohno S; Kasada A; Hosomichi K; Sato T; Kurayoshi K; Kobayashi M; Tadokoro Y; Kasahara A; Shoulkamy MI; Xiao B; Worley PF; Takahashi C; Tajima A; Hirao A
Biochem Biophys Res Commun; 2022 Sep; 621():74-79. PubMed ID: 35810594
[TBL] [Abstract] [Full Text] [Related]
12. Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid leukemia with Adverse Genetic Factors.
Ikeda D; Chi S; Uchiyama S; Nakamura H; Guo YM; Yamauchi N; Yuda J; Minami Y
Int J Mol Sci; 2022 May; 23(11):. PubMed ID: 35682627
[TBL] [Abstract] [Full Text] [Related]
13. Genome-Wide Gene Expression Profiling Defines the Mechanism of Anticancer Effect of Colorectal Cancer Cell-Derived Conditioned Medium on Acute Myeloid leukemia.
Lee JE; Kwon CS; Jeon BE; Kim WR; Lee DH; Koh S; Kim HS; Kim SW
Genes (Basel); 2022 May; 13(5):. PubMed ID: 35627268
[TBL] [Abstract] [Full Text] [Related]
14. Therapeutic targeting of LCK tyrosine kinase and mtor signaling in T-cell acute lymphoblastic leukemia.
Laukkanen S; Veloso A; Yan C; Oksa L; Alpert EJ; Do D; Hyvärinen N; McCarthy K; Adhikari A; Yang Q; Iyer S; Garcia SP; Pello A; Ruokoranta T; Moisio S; Adhikari S; Yoder JA; Gallagher K; Whelton L; Allen JR; Jin AH; Loontiens S; Heinäniemi M; Kelliher M; Heckman CA; Lohi O; Langenau DM
Blood; 2022 Oct; 140(17):1891-1906. PubMed ID: 35544598
[TBL] [Abstract] [Full Text] [Related]
15. USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mtor Signaling.
Wang D; Jin X; Lei M; Jiang Y; Liu Y; Yu F; Guo Y; Han B; Yang Y; Sun W; Liu Y; Zeng G; Liu F; Hu J; Chen X
Int J Biol Sci; 2022; 18(6):2452-2471. PubMed ID: 35414770
[TBL] [Abstract] [Full Text] [Related]
16. Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL).
Ehm P; Grottke A; Bettin B; Jücker M
Cell Signal; 2022 May; 93():110301. PubMed ID: 35259456
[TBL] [Abstract] [Full Text] [Related]
17. Integrative genomic analysis of a novel small nucleolar RNAs prognostic signature in patients with acute myelocytic leukemia.
Huang R; Liao X; Li Q
Math Biosci Eng; 2022 Jan; 19(3):2424-2452. PubMed ID: 35240791
[TBL] [Abstract] [Full Text] [Related]
18. Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance.
Fleischmann M; Fischer M; Schnetzke U; Fortner C; Kirkpatrick J; Heidel FH; Hochhaus A; Scholl S
Cells; 2021 Nov; 10(11):. PubMed ID: 34831215
[TBL] [Abstract] [Full Text] [Related]
19. Protein Arginine Methyltransferase 5 Promotes the Migration of AML Cells by Regulating the Expression of Leukocyte Immunoglobulin-Like Receptor B4.
Zhao L; Cheng B; Xiong J; Ma D; Liu X; Wang L; Zhang X; Wang J
Biomed Res Int; 2021; 2021():7329072. PubMed ID: 34712735
[TBL] [Abstract] [Full Text] [Related]
20. GATM-Mediated Creatine Biosynthesis Enables Maintenance of FLT3-ITD-Mutant Acute Myeloid leukemia.
Zhang Y; Newsom KJ; Zhang M; Kelley JS; Starostik P
Mol Cancer Res; 2022 Feb; 20(2):293-304. PubMed ID: 34635505
[TBL] [Abstract] [Full Text] [Related]
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