BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED
174 results:

  • 1. A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations.
    Saldana-Guerrero IM; Montano-Gutierrez LF; Boswell K; Hafemeister C; Poon E; Shaw LE; Stavish D; Lea RA; Wernig-Zorc S; Bozsaky E; Fetahu IS; Zoescher P; Pötschger U; Bernkopf M; Wenninger-Weinzierl A; Sturtzel C; Souilhol C; Tarelli S; Shoeb MR; Bozatzi P; Rados M; Guarini M; Buri MC; Weninger W; Putz EM; Huang M; Ladenstein R; Andrews PW; Barbaric I; Cresswell GD; Bryant HE; Distel M; Chesler L; Taschner-Mandl S; Farlik M; Tsakiridis A; Halbritter F
    Nat Commun; 2024 May; 15(1):3745. PubMed ID: 38702304
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2
    Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Integrated analysis of transcriptome and genome variations in pediatric T cell acute lymphoblastic leukemia: data from north Indian tertiary care center.
    Singh M; Sharma P; Bhatia P; Trehan A; Thakur R; Sreedharanunni S
    BMC Cancer; 2024 Mar; 24(1):325. PubMed ID: 38459434
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. n-myc regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia.
    Peramangalam PS; Surapally S; Veltri AJ; Zheng S; Burns R; Zhu N; Rao S; Muller-Tidow C; Bushweller JH; Pulikkan JA
    Sci Adv; 2024 Mar; 10(9):eadh8493. PubMed ID: 38416825
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. AF1q is a universal marker of neuroblastoma that sustains n-myc expression and drives tumorigenesis.
    Oskouian B; Lee JY; Asgharzadeh S; Khan R; Zhang M; Weisbrod JR; Choi YJ; Puri L; Aguilar AE; Zhao P; Saba JD
    Oncogene; 2024 Apr; 43(16):1203-1213. PubMed ID: 38413795
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. [Clinical characteristics and prognosis of 28 cases of infant acute lymphoblastic leukemia].
    Shi Y; Lu Y; Zhang RD; Zhang YY; Lin W; Yu JJ; Wu Y; Fan J; Qi PJ; Huang PL; Cai LX; Huang Q; Zhang P; Sun YM; Liu Y; Zheng HY
    Zhonghua Er Ke Za Zhi; 2024 Jan; 62(1):49-54. PubMed ID: 38154977
    [No Abstract]    [Full Text] [Related]  

  • 7. Comparative Analysis of the Embryonal Brain Tumors Based on Their Molecular Features.
    Shcherbina V; Kovalevska L; Pedachenko E; Malysheva T; Kashuba E
    Discov Med; 2023 Oct; 35(178):733-749. PubMed ID: 37811612
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.
    Frank D; Patnana PK; Vorwerk J; Mao L; Gopal LM; Jung N; Hennig T; Ruhnke L; Frenz JM; Kuppusamy M; Autry R; Wei L; Sun K; Mohammed Ahmed HM; Künstner A; Busch H; Müller H; Hutter S; Hoermann G; Liu L; Xie X; Al-Matary Y; Nimmagadda SC; Cano FC; Heuser M; Thol F; Göhring G; Steinemann D; Thomale J; Leitner T; Fischer A; Rad R; Röllig C; Altmann H; Kunadt D; Berdel WE; Hüve J; Neumann F; Klingauf J; Calderon V; Opalka B; Dührsen U; Rosenbauer F; Dugas M; Varghese J; Reinhardt HC; von Bubnoff N; Möröy T; Lenz G; Batcha AMN; Giorgi M; Selvam M; Wang E; McWeeney SK; Tyner JW; Stölzel F; Mann M; Jayavelu AK; Khandanpour C
    Blood; 2023 Dec; 142(25):2175-2191. PubMed ID: 37756525
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Endothelial-derived small extracellular vesicles support B-cell acute lymphoblastic leukemia development.
    Huang D; Yuan Y; Cao L; Zhang D; Jiang Y; Zhang Y; Chen C; Yu Z; Xie L; Wei Y; Wan J; Zheng J
    Cell Oncol (Dordr); 2024 Feb; 47(1):129-140. PubMed ID: 37751067
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. TAL1 hijacks mycn enhancer that induces mycn expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia.
    Tan SH; Tan TK; Yokomori R; Liao M; Huang XZ; Yeoh AEJ; Sanda T
    Leukemia; 2023 Oct; 37(10):1969-1981. PubMed ID: 37591943
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.
    Wang X; Rong S; Sun Y; Yin B; Yang X; Lu X; Sun H; Yan Y; Sun G; Liang Y; Wang P; Xie S; Li Y
    Oncol Rep; 2023 Aug; 50(2):. PubMed ID: 37350410
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Diagnostic Utility of GATA3 and ISL1 in Differentiating Neuroblastoma From Other Pediatric Malignant Small Round Blue Cell Tumors.
    Mohanty SK; Diwaker P; Mishra SK; Jha S; Lobo A; Panda SP; Sharma S; Kumar M; Arora S; Mallik V; Jain D; Jain E; Chakrabarti I; Varshney J; Beg A; Dixit M; Baisakh MR; Naik S; Sahoo SK; Akgul M; Balzer BL; Amin MB; Parwani AV
    Int J Surg Pathol; 2024 Apr; 32(2):294-303. PubMed ID: 37312579
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
    Alburquerque-Bejar JJ; Navajas-Chocarro P; Saigi M; Ferrero-Andres A; Morillas JM; Vilarrubi A; Gomez A; Mate JL; Munoz-Marmol AM; Romero OA; Blecua P; Davalos V; Esteller M; Pros E; Llabata P; Torres-Diz M; Esteve-Codina A; Sanchez-Cespedes M
    Cell Rep Med; 2023 Apr; 4(4):101006. PubMed ID: 37044092
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner.
    Castell A; Yan Q; Fawkner K; Bazzar W; Zhang F; Wickström M; Alzrigat M; Franco M; Krona C; Cameron DP; Dyberg C; Olsen TK; Verschut V; Schmidt L; Lim SY; Mahmoud L; Hydbring P; Lehmann S; Baranello L; Nelander S; Johnsen JI; Larsson LG
    Cancer Res Commun; 2022 Mar; 2(3):182-201. PubMed ID: 36874405
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults.
    Arniani S; Pierini V; Pellanera F; Matteucci C; Di Giacomo D; Bardelli V; Quintini M; Mavridou E; Lema Fernandez AG; Nardelli C; Moretti M; Gorello P; Crescenzi B; Romoli S; Beacci D; Cerrano M; Fracchiolla N; Sica S; Forghieri F; Giglio F; Dargenio M; Elia L; La Starza R; Mecucci C
    Leukemia; 2022 Nov; 36(11):2577-2585. PubMed ID: 35974102
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Aberrant mycn expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma.
    Vanden Bempt M; Debackere K; Demeyer S; Van Thillo Q; Meeuws N; Prieto C; Provost S; Mentens N; Jacobs K; Gielen O; Nittner D; Ogawa S; Kataoka K; Graux C; Tousseyn T; Cools J; Dierickx D
    Blood; 2022 Dec; 140(23):2463-2476. PubMed ID: 35960849
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Multiple cells of origin in common with various types of mouse n-myc acute leukemia.
    Bai H; Zhang Q; Zhang S; Wang J; Luo B; Dong Y; Gao J; Cheng T; Dong F; Ema H
    Leuk Res; 2022 Jun; 117():106843. PubMed ID: 35512442
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Prognostic significance of NT5E/CD73 in neuroblastoma and its function in CSC stemness maintenance.
    Jain D; Somasundaram DB; Aravindan S; Yu Z; Baker A; Esmaeili A; Aravindan N
    Cell Biol Toxicol; 2023 Jun; 39(3):967-989. PubMed ID: 34773529
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme.
    Urban-Wójciuk Z; Graham A; Barker K; Kwok C; Sbirkov Y; Howell L; Campbell J; Woster PM; Poon E; Petrie K; Chesler L
    Cancer Gene Ther; 2022 Jul; 29(7):940-950. PubMed ID: 34522028
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Age related gene DST represents an independent prognostic factor for mycn non-amplified neuroblastoma.
    Wang H; Wang X; Xu L; Zhang J; Cao H
    BMC Pediatr; 2021 Jun; 21(1):272. PubMed ID: 34116676
    [TBL] [Abstract] [Full Text] [Related]  


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