BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NCOR1, hCIT529I10, 9611, ENSG00000141027, N-CoR, MGC104216, TRAC1, O75376, hN-CoR, KIAA1047
80 results:

  • 1. [Study of a patient with Myelodysplastic/myeloproliferative neoplasm with co-morbid neutrophilia and a novel ncor1::GLYR1 fusion gene].
    Lei Y; Zhao X; Zhao H; Cheng Y; Wang S; Li J; Zhu Y
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2024 Apr; 41(4):404-410. PubMed ID: 38565504
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Nuclear corepressors ncor1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.
    Lee RD; Knutson TP; Munro SA; Miller JT; Heltemes-Harris LM; Mullighan CG; Jepsen K; Farrar MA
    Nat Immunol; 2022 Dec; 23(12):1763-1776. PubMed ID: 36316474
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clinical and demographic factors contributing to asparaginase-associated toxicities in children with acute lymphoblastic leukemia.
    Dharia P; Swartz MD; Bernhardt MB; Chen H; Gramatges MM; Lupo PJ; Brown AL; Scheurer ME
    Leuk Lymphoma; 2022 Dec; 63(12):2948-2954. PubMed ID: 35895075
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. [Assessment of the leukemogenic mechanism of Ph-like acute lymphocytic leukemia for the identification of a novel therapeutic target].
    Imamura T
    Rinsho Ketsueki; 2021; 62(8):1131-1138. PubMed ID: 34497200
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERα nuclear/genomic to extra-nuclear/non genomic actions.
    Jehanno C; Percevault F; Boujrad N; Le Goff P; Fontaine C; Arnal JF; Primig M; Pakdel F; Michel D; Métivier R; Flouriot G
    Mol Cell Endocrinol; 2021 Jun; 530():111282. PubMed ID: 33894309
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Nuclear DEK preserves hematopoietic stem cells potential via ncor1/HDAC3-Akt1/2-mTOR axis.
    Chen Z; Huo D; Li L; Liu Z; Li Z; Xu S; Huang Y; Wu W; Zhou C; Liu Y; Kuang M; Wu F; Li H; Qian P; Song G; Wu X; Chen J; Hou Y
    J Exp Med; 2021 May; 218(5):. PubMed ID: 33755722
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion.
    Chen-Wichmann L; Shvartsman M; Preiss C; Hockings C; Windisch R; Redondo Monte E; Leubolt G; Spiekermann K; Lausen J; Brendel C; Grez M; Greif PA; Wichmann C
    Oncogene; 2019 Jan; 38(2):261-272. PubMed ID: 30093631
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan.
    Imamura T; Kiyokawa N; Kato M; Imai C; Okamoto Y; Yano M; Ohki K; Yamashita Y; Kodama Y; Saito A; Mori M; Ishimaru S; Deguchi T; Hashii Y; Shimomura Y; Hori T; Kato K; Goto H; Ogawa C; Koh K; Taki T; Manabe A; Sato A; Kikuta A; Adachi S; Horibe K; Ohara A; Watanabe A; Kawano Y; Ishii E; Shimada H
    Blood Cancer J; 2016 May; 6(5):e419. PubMed ID: 27176795
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of novel kinase fusion transcripts in paediatric B cell precursor acute lymphoblastic leukaemia with IKZF1 deletion.
    Yano M; Imamura T; Asai D; Kiyokawa N; Nakabayashi K; Matsumoto K; Deguchi T; Hashii Y; Honda YK; Hasegawa D; Sasahara Y; Ishii M; Kosaka Y; Kato K; Shima M; Hori H; Yumura-Yagi K; Hara J; Oda M; Horibe K; Ichikawa H; Sato A
    Br J Haematol; 2015 Dec; 171(5):813-7. PubMed ID: 26404892
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Integrative genomic analysis in K562 chronic myelogenous leukemia cells reveals that proximal ncor1 binding positively regulates genes that govern erythroid differentiation and Imatinib sensitivity.
    Long MD; van den Berg PR; Russell JL; Singh PK; Battaglia S; Campbell MJ
    Nucleic Acids Res; 2015 Sep; 43(15):7330-48. PubMed ID: 26117541
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Genome-wide co-occupancy of AML1-ETO and n-cor defines the t(8;21) AML signature in leukemic cells.
    Trombly DJ; Whitfield TW; Padmanabhan S; Gordon JA; Lian JB; van Wijnen AJ; Zaidi SK; Stein JL; Stein GS
    BMC Genomics; 2015 Apr; 16(1):309. PubMed ID: 25928846
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Synthesis and evaluation of bisbenzylidenedioxotetrahydrothiopranones as activators of endoplasmic reticulum (ER) stress signaling pathways and apoptotic cell death in acute promyelocytic leukemic cells.
    Tan KL; Ali A; Du Y; Fu H; Jin HX; Chin TM; Khan M; Go ML
    J Med Chem; 2014 Jul; 57(14):5904-18. PubMed ID: 24960549
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Novel treatment of acute promyelocytic leukemia: As₂O₃, retinoic acid and retinoid pharmacology.
    Zhu G
    Curr Pharm Biotechnol; 2013; 14(9):849-58. PubMed ID: 24433507
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Cooperation between RUNX1-ETO9a and novel transcriptional partner KLF6 in upregulation of Alox5 in acute myeloid leukemia.
    DeKelver RC; Lewin B; Lam K; Komeno Y; Yan M; Rundle C; Lo MC; Zhang DE
    PLoS Genet; 2013; 9(10):e1003765. PubMed ID: 24130502
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Akt-induced phosphorylation of n-cor at serine 1450 contributes to its misfolded conformational dependent loss (MCDL) in acute myeloid leukemia of the M5 subtype.
    Nin DS; Ali AB; Okumura K; Asou N; Chen CS; Chng WJ; Khan M
    PLoS One; 2013; 8(8):e70891. PubMed ID: 23940660
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential.
    DeKelver RC; Yan M; Ahn EY; Shia WJ; Speck NA; Zhang DE
    Blood; 2013 May; 121(18):3714-7. PubMed ID: 23426948
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (n-cor) protein as a basis for selective activity.
    Tan KL; Koh SB; Ee RP; Khan M; Go ML
    ChemMedChem; 2012 Sep; 7(9):1567-79. PubMed ID: 22887959
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Role of misfolded n-cor mediated transcriptional deregulation of Flt3 in acute monocytic leukemia (AML)-M5 subtype.
    Nin DS; Kok WK; Li F; Takahashi S; Chng WJ; Khan M
    PLoS One; 2012; 7(4):e34501. PubMed ID: 22514634
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. HDAC inhibitors sodium butyrate and sodium valproate do not affect human ncor1 and ncor2 gene expression in HL-60 cells.
    Vrba J; Trtkova K; Ulrichova J
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2011 Sep; 155(3):259-62. PubMed ID: 22286811
    [TBL] [Abstract] [Full Text] [Related]  


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