BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
81 results:

  • 1. Inhibition of nrf2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid leukemia.
    Jebanesan DZP; Illangeswaran RSS; Rajamani BM; Vidhyadharan RT; Das S; Bijukumar NK; Balakrishnan B; Mathews V; Velayudhan SR; Balasubramanian P
    Ann Hematol; 2024 Jun; 103(6):1919-1929. PubMed ID: 38630133
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Roles of Glutathione and AP-1 in the Enhancement of Vitamin D-Induced Differentiation by Activators of the nrf2 Signaling Pathway in Acute Myeloid leukemia Cells.
    Jramne-Saleem Y; Danilenko M
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396960
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Activation of APE1 modulates nrf2 protected against acute liver injury by inhibit hepatocyte ferroptosis and promote hepatocyte autophagy.
    Diao J; Fan H; Zhang J; Fu X; Liao R; Zhao P; Huang W; Huang S; Liao H; Yu J; Pan D; Wang M; Xiao W; Wen X
    Int Immunopharmacol; 2024 Feb; 128():111529. PubMed ID: 38244516
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Venetoclax and Hypomethylating Agent Combination in Myeloid Malignancies: Mechanisms of Synergy and Challenges of Resistance.
    Mishra R; Zokaei Nikoo M; Veeraballi S; Singh A
    Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203655
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-nrf2 signaling pathway in chronic myeloid leukemia cells.
    Xia Q; Xie J; Zhang J; Zhang L; Zhou Y; Zhu B; Wu Y; Yang Z; Li J
    Chem Biol Interact; 2024 Jan; 387():110819. PubMed ID: 38000454
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Targeting the NF-E2-related factor 2 pathway for overcoming leukemia.
    Harifi-Mood MS; Daroudi M; Darroudi M; Naseri K; Samarghandian S; Farkhondeh T
    Int J Biol Macromol; 2023 Dec; 253(Pt 8):127594. PubMed ID: 37890739
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line.
    Hirasawa I; Odagiri H; Park G; Sanghavi R; Oshita T; Togi A; Yoshikawa K; Mizutani K; Takeuchi Y; Kobayashi H; Katagiri S; Iwata T; Aoki A
    PLoS One; 2023; 18(10):e0292267. PubMed ID: 37851686
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Duality of Valproic Acid Effects on Inflammation, Oxidative Stress and Autophagy in Human Eosinophilic Cells.
    Uzel G; Oylumlu E; Durmus L; Ciraci C
    Int J Mol Sci; 2023 Aug; 24(17):. PubMed ID: 37686250
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. ATO Increases ROS Production and Apoptosis of Cells by Enhancing Calpain-Mediated Degradation of the Cancer Survival Protein TG2.
    Jambrovics K; Póliska S; Scholtz B; Uray IP; Balajthy Z
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446117
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of nrf2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia.
    Villa-Morales M; Pérez-Gómez L; Pérez-Gómez E; López-Nieva P; Fernández-Navarro P; Santos J
    Int J Mol Sci; 2023 Jun; 24(12):. PubMed ID: 37373496
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the nrf2/NQO1 axis.
    Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B
    Cell Signal; 2023 May; 105():110626. PubMed ID: 36758683
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Nuclear factor nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    Shang Q; Pan C; Zhang X; Yang T; Hu T; Zheng L; Cao S; Feng C; Hu X; Chai X; Wang J; Fang Q
    J Biol Chem; 2023 Jan; 299(1):102798. PubMed ID: 36528059
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies.
    Wild SA; Cannell IG; Nicholls A; Kania K; Bressan D; ; Hannon GJ; Sawicka K
    Elife; 2022 Dec; 11():. PubMed ID: 36525288
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. nrf2 affects hydroquinone-induces cell cycle arrest through the p16/pRb signaling pathway and antioxidant enzymes.
    Chen L; Zhai L; Gao Y; Cui Z; Yu L; Zhu D; Tang H; Luo H
    Ecotoxicol Environ Saf; 2023 Jan; 249():114389. PubMed ID: 36508791
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Omics-based identification of an nrf2-related auranofin resistance signature in cancer: Insights into drug repurposing.
    Falchetti M; Delgobo M; Zancanaro H; Almeida K; das Neves RN; Dos Santos B; Stefanes NM; Bishop A; Santos-Silva MC; Zanotto-Filho A
    Comput Biol Med; 2023 Jan; 152():106347. PubMed ID: 36493734
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RARα-nrf2 complex.
    Wang L; Zhang Q; Ye L; Ye X; Yang W; Zhang H; Zhou X; Ren Y; Ma L; Zhang X; Mei C; Xu G; Li K; Luo Y; Jiang L; Lin P; Zhu S; Lang W; Wang Y; Shen C; Han Y; Liu X; Yang H; Lu C; Sun J; Jin J; Tong H
    Br J Cancer; 2023 Feb; 128(4):691-701. PubMed ID: 36482192
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Triptolide promotes ferroptosis by suppressing nrf2 to overcome leukemia cell resistance to doxorubicin.
    Wu X; Chen S; Huang K; Lin G
    Mol Med Rep; 2023 Jan; 27(1):. PubMed ID: 36453238
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Anti-Leukemic Activity of Brassica-Derived Bioactive Compounds in HL-60 Myeloid leukemia Cells.
    Núñez-Sánchez MÁ; Martínez-Sánchez MA; Verdejo-Sánchez M; García-Ibáñez P; Oliva Bolarín A; Ramos-Molina B; Moreno DA; Ruiz-Alcaraz AJ
    Int J Mol Sci; 2022 Nov; 23(21):. PubMed ID: 36362202
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating nrf2/NQO1 pathway.
    Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B
    Cell Commun Signal; 2022 Oct; 20(1):168. PubMed ID: 36303144
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. WASH regulates the oxidative stress nrf2/ARE pathway to inhibit proliferation and promote apoptosis of HeLa cells under the action of Jolkinolide B.
    Hong Y; Liu J; Kong W; Li H; Cui Y; Liu Y; Deng Z; Ma D; Zhang K; Li J; Li M
    PeerJ; 2022; 10():e13499. PubMed ID: 35855902
    [TBL] [Abstract] [Full Text] [Related]  


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