BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NOTCH2, Q04721, 4853, ENSG00000134250, AGS2, hN2 AND Treatment
19 results:

  • 1. Chronic Lymphocytic leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing.
    Grants JM; May C; Bridgers J; Huang S; Gillis S; Meissner B; Boyle M; Ben-Neriah S; Hung S; Duns G; Hilton L; Gerrie AS; Marra M; Kridel R; Sabatini PJB; Steidl C; Scott DW; Karsan A
    Clin Chem; 2024 Jan; 70(1):273-284. PubMed ID: 38175592
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. NOTCH pathway mutation contributes to inferior prognosis in HBV-infected chronic lymphocytic leukemia.
    Shang CY; Bei LY; Wu JZ; Sheng HR; Yin H; Liang JH; Wang L; Li JY; Li Y; Xu W
    Ann Hematol; 2024 Mar; 103(3):833-841. PubMed ID: 37993586
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Molecular associations of response to the new-generation BTK inhibitor zanubrutinib in marginal zone lymphoma.
    Tatarczuch M; Waltham M; Shortt J; Polekhina G; Hawkes EA; Ho SJ; Trotman J; Brasacchio D; Co M; Li J; Ramakrishnan V; Dunne K; Opat SS; Gregory GP
    Blood Adv; 2023 Jul; 7(14):3531-3539. PubMed ID: 36947202
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border.
    Grant AH; Ayala-Marin YM; Mohl JE; Robles-Escajeda E; Rodriguez G; Dutil J; Kirken RA
    Int J Environ Res Public Health; 2021 Jul; 18(14):. PubMed ID: 34299796
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Targeting Nuclear notch2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL.
    Hubmann R; Schnabl S; Araghi M; Schmidl C; Rendeiro AF; Hilgarth M; Demirtas D; Ali F; Staber PB; Valent P; Zielinski C; Jäger U; Shehata M
    Cells; 2020 Jun; 9(6):. PubMed ID: 32570839
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines.
    van Alphen C; Cloos J; Beekhof R; Cucchi DGJ; Piersma SR; Knol JC; Henneman AA; Pham TV; van Meerloo J; Ossenkoppele GJ; Verheul HMW; Janssen JJWM; Jimenez CR
    Mol Cell Proteomics; 2020 May; 19(5):884-899. PubMed ID: 32102969
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Mutational spectrum and associations with clinical features in patients with acute myeloid leukaemia based on next‑generation sequencing.
    Li Y; Lv X; Ge X; Yuan D; Ding M; Zhen C; Zhao W; Liu X; Wang X; Xu H; Li Y; Wang X
    Mol Med Rep; 2019 May; 19(5):4147-4158. PubMed ID: 30942411
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Cross-linking by epichlorohydrin and diepoxybutane correlates with cytotoxicity and leads to apoptosis in human leukemia (HL-60) cells.
    Le PM; Silvestri VL; Redstone SC; Dunn JB; Millard JT
    Toxicol Appl Pharmacol; 2018 Aug; 352():19-27. PubMed ID: 29792945
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate.
    Kim SH; Singh SV
    Breast Cancer Res Treat; 2015 Feb; 149(3):681-92. PubMed ID: 25663545
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Mutational spectrum of adult T-ALL.
    Neumann M; Vosberg S; Schlee C; Heesch S; Schwartz S; Gökbuget N; Hoelzer D; Graf A; Krebs S; Bartram I; Blum H; Brüggemann M; Hecht J; Bohlander SK; Greif PA; Baldus CD
    Oncotarget; 2015 Feb; 6(5):2754-66. PubMed ID: 25595890
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias.
    Athanasakis E; Melloni E; Rigolin GM; Agnoletto C; Voltan R; Vozzi D; Piscianz E; Segat L; Dal Monego S; Cuneo A; Secchiero P; Zauli G
    Oncotarget; 2014 Dec; 5(24):12635-45. PubMed ID: 25587027
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Changes in gene expression profile in two multidrug resistant cell lines derived from a same drug sensitive cell line.
    Moreira MA; Bagni C; de Pinho MB; Mac-Cormick TM; dos Santos Mota M; Pinto-Silva FE; Daflon-Yunes N; Rumjanek VM
    Leuk Res; 2014 Aug; 38(8):983-7. PubMed ID: 24996974
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Post-transcriptional silencing of notch2 mRNA in chronic lymphocytic [corrected] leukemic cells of B-CLL patients.
    Fatima K; Paracha RZ; Qadri I
    Mol Biol Rep; 2012 May; 39(5):5059-67. PubMed ID: 22161246
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. GSI-I (Z-LLNle-CHO) inhibits γ-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.
    Meng X; Matlawska-Wasowska K; Girodon F; Mazel T; Willman CL; Atlas S; Chen IM; Harvey RC; Hunger SP; Ness SA; Winter SS; Wilson BS
    Leukemia; 2011 Jul; 25(7):1135-46. PubMed ID: 21494254
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Notch promotes radioresistance of glioma stem cells.
    Wang J; Wakeman TP; Lathia JD; Hjelmeland AB; Wang XF; White RR; Rich JN; Sullenger BA
    Stem Cells; 2010 Jan; 28(1):17-28. PubMed ID: 19921751
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Overexpression of GSTA2 protects against cell cycle arrest and apoptosis induced by the DNA inter-strand crosslinking nitrogen mustard, mechlorethamine.
    Xie J; Shults K; Flye L; Jiang F; Head DR; Briggs RC
    J Cell Biochem; 2005 May; 95(2):339-51. PubMed ID: 15778998
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The lack of effects of alkylating agents on mammalian cell membranes.
    Ankel EG; Ring BJ; Lai CS; Holcenberg JS
    Int J Tissue React; 1986; 8(5):347-54. PubMed ID: 3023251
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Adjuvant low dose radiation in childhood T cell leukaemia/lymphoma (report from the United Kingdom Childrens' Cancer Study Group--UKCCSG).
    Mott MG; Chessells JM; Willoughby ML; Mann JR; Morris-Jones PH; Malpas JS; Palmer MK
    Br J Cancer; 1984 Oct; 50(4):457-62. PubMed ID: 6333247
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Trisethylene-imino-s-triazine (triethylene melamine or TEM) in the treatment of neoplastic diseases.
    SHIMKIN MB; BIERMAN HR; KELLY KH; LOWENHAUPT E; FURST A
    Calif Med; 1951 Jul; 75(1):26-34. PubMed ID: 14848718
    [TBL] [Abstract] [Full Text] [Related]  


    of 1.