BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NSD1, FLJ44628, 64324, ENSG00000165671, Q96L73, FLJ22263, DKFZp666C163, ARA267, STO, SOTOS
88 results:

  • 1. [Clinical significance of monitoring NUP98::nsd1 fusion genes before and after allogeneic hematopoietic stem cell transplantation].
    Shang YK; Pan XA; Chang YJ; Qin YQ; Wang Y; Yan CH; Sun YQ; Huang XJ; Zhao XS
    Zhonghua Xue Ye Xue Za Zhi; 2023 Dec; 44(12):1010-1015. PubMed ID: 38503524
    [No Abstract]    [Full Text] [Related]  

  • 2. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
    Abla O; Ries RE; Triche T; Gerbing RB; Hirsch B; Raimondi S; Cooper T; Farrar JE; Buteyn N; Harmon LM; Wen H; Deshpande AJ; Kolb EA; Gamis AS; Aplenc R; Alonzo T; Meshinchi S
    Blood Adv; 2024 Apr; 8(8):2005-2017. PubMed ID: 38306602
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prognostic impact of cooccurring mutations in FLT3-ITD pediatric acute myeloid leukemia.
    Tarlock K; Gerbing RB; Ries RE; Smith JL; Leonti A; Huang BJ; Kirkey D; Robinson L; Peplinksi JH; Lange B; Cooper TM; Gamis AS; Kolb EA; Aplenc R; Pollard JA; Alonzo TA; Meshinchi S
    Blood Adv; 2024 May; 8(9):2094-2103. PubMed ID: 38295280
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia.
    Hoffmeister LM; Suttorp J; Walter C; Antoniou E; Behrens YL; Göhring G; Awada A; von Neuhoff N; Reinhardt D; Schneider M
    Leukemia; 2024 Mar; 38(3):538-544. PubMed ID: 38086945
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Clinical implications of NUP98::nsd1 fusion at diagnosis in adult FLT3-ITD positive AML.
    Miyajima T; Onozawa M; Yoshida S; Miyashita N; Kimura H; Takahashi S; Yokoyama S; Matsukawa T; Goto H; Sugita J; Fujisawa S; Hidaka D; Ogasawara R; Mori A; Matsuoka S; Shigematsu A; Wakasa K; Kasahara I; Saga T; Hashiguchi J; Takeda Y; Ibata M; Yutaka T; Fujimoto K; Kondo T; Teshima T
    Eur J Haematol; 2023 Oct; 111(4):620-627. PubMed ID: 37465857
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.
    Khella MS; Schnee P; Weirich S; Bui T; Bröhm A; Bashtrykov P; Pleiss J; Jeltsch A
    J Biol Chem; 2023 Jun; 299(6):104796. PubMed ID: 37150325
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
    Liu Y; Klein J; Bajpai R; Dong L; Tran Q; Kolekar P; Smith JL; Ries RE; Huang BJ; Wang YC; Alonzo TA; Tian L; Mulder HL; Shaw TI; Ma J; Walsh MP; Song G; Westover T; Autry RJ; Gout AM; Wheeler DA; Wan S; Wu G; Yang JJ; Evans WE; Loh M; Easton J; Zhang J; Klco JM; Meshinchi S; Brown PA; Pruett-Miller SM; Ma X
    Nat Commun; 2023 Apr; 14(1):1739. PubMed ID: 37019972
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Comprehensive molecular and clinical characterization of
    Bertrums EJM; Smith JL; Harmon L; Ries RE; Wang YJ; Alonzo TA; Menssen AJ; Chisholm KM; Leonti AR; Tarlock K; Ostronoff F; Pogosova-Agadjanyan EL; Kaspers GJL; Hasle H; Dworzak M; Walter C; Muhlegger N; Morerio C; Pardo L; Hirsch B; Raimondi S; Cooper TM; Aplenc R; Gamis AS; Kolb EA; Farrar JE; Stirewalt D; Ma X; Shaw TI; Furlan SN; Brodersen LE; Loken MR; Van den Heuvel-Eibrink MM; Zwaan CM; Triche TJ; Goemans BF; Meshinchi S
    Haematologica; 2023 Aug; 108(8):2044-2058. PubMed ID: 36815378
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia.
    Kaburagi T; Shiba N; Yamato G; Yoshida K; Tabuchi K; Ohki K; Ishikita E; Hara Y; Shiraishi Y; Kawasaki H; Sotomatsu M; Takizawa T; Taki T; Kiyokawa N; Tomizawa D; Horibe K; Miyano S; Taga T; Adachi S; Ogawa S; Hayashi Y
    Genes Chromosomes Cancer; 2023 Apr; 62(4):202-209. PubMed ID: 36448876
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of alternative transcripts of nsd1 gene in sotos Syndrome patients and healthy subjects.
    Conteduca G; Testa B; Baldo C; Arado A; Malacarne M; Candiano G; Garbarino A; Coviello DA; Cantoni C
    Gene; 2023 Jan; 851():146970. PubMed ID: 36261088
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia.
    Ren Z; Kim A; Huang YT; Pi WC; Gong W; Yu X; Qi J; Jin J; Cai L; Roeder RG; Chen WY; Wang GG
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35217626
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. SMARCA5 interacts with NUP98-nsd1 oncofusion protein and sustains hematopoietic cells transformation.
    Jevtic Z; Matafora V; Casagrande F; Santoro F; Minucci S; Garre' M; Rasouli M; Heidenreich O; Musco G; Schwaller J; Bachi A
    J Exp Clin Cancer Res; 2022 Jan; 41(1):34. PubMed ID: 35073946
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Role of nsd1 as potential therapeutic target in tumor.
    Yang C; Wang K; Liang Q; Tian TT; Zhong Z
    Pharmacol Res; 2021 Nov; 173():105888. PubMed ID: 34536546
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Mixed phenotype acute leukemia in a child associated with a NUP98-nsd1 fusion and NRAS p.Gly61Arg mutation.
    Ganapathi SS; Raikar SS; Yatsenko SA; Djokic M; Bukowinski A
    Cancer Rep (Hoboken); 2021 Aug; 4(4):e1372. PubMed ID: 33784031
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Hyperleukocytosis predicts inferior clinical outcome in pediatric acute myeloid leukemia.
    Xu LH; Wang JW; Wang Y; Yang FY
    Hematology; 2020 Dec; 25(1):507-514. PubMed ID: 33317436
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Oncology Group.
    Chisholm KM; Heerema-McKenney AE; Choi JK; Smith J; Ries RE; Hirsch BA; Raimondi SC; Alonzo TA; Wang YC; Aplenc R; Sung L; Gamis AS; Meshinchi S; Kahwash SB
    Blood Adv; 2020 Dec; 4(23):6000-6008. PubMed ID: 33284945
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Covalent inhibition of nsd1 histone methyltransferase.
    Huang H; Howard CA; Zari S; Cho HJ; Shukla S; Li H; Ndoj J; González-Alonso P; Nikolaidis C; Abbott J; Rogawski DS; Potopnyk MA; Kempinska K; Miao H; Purohit T; Henderson A; Mapp A; Sulis ML; Ferrando A; Grembecka J; Cierpicki T
    Nat Chem Biol; 2020 Dec; 16(12):1403-1410. PubMed ID: 32868895
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. NUP98-nsd1 Driven MDS/MPN in Childhood Masquerading as JMML.
    Behnert A; Lee AG; Young EP; Breese MR; Leung SG; Behroozfard I; Maruffi M; Sweet-Cordero EA; Dvorak CC; Chu J; Stieglitz E
    J Pediatr Hematol Oncol; 2021 Aug; 43(6):e808-e811. PubMed ID: 32815876
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Synthesis and toxicity assessment of Fe
    Eshaghi Malekshah R; Fahimirad B; Aallaei M; Khaleghian A
    Drug Deliv; 2020 Dec; 27(1):1201-1217. PubMed ID: 32772887
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia.
    Leonards K; Almosailleakh M; Tauchmann S; Bagger FO; Thirant C; Juge S; Bock T; Méreau H; Bezerra MF; Tzankov A; Ivanek R; Losson R; Peters AHFM; Mercher T; Schwaller J
    Nat Commun; 2020 Jun; 11(1):2807. PubMed ID: 32533074
    [TBL] [Abstract] [Full Text] [Related]  


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