Terms: = Leukemia AND NSD1, FLJ44628, 64324, ENSG00000165671, Q96L73, FLJ22263, DKFZp666C163, ARA267, STO, SOTOS AND Prognosis
24 results:
1. NUP98::nsd1 and FLT3/ITD co-expression is an independent predictor of poor prognosis in pediatric AML patients.
Wang JW; Yu-Li ; Yang XG; Xu LH
BMC Pediatr; 2024 Aug; 24(1):547. PubMed ID: 39182032
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2. [Clinical significance of monitoring NUP98::nsd1 fusion genes before and after allogeneic hematopoietic stem cell transplantation].
Shang YK; Pan XA; Chang YJ; Qin YQ; Wang Y; Yan CH; Sun YQ; Huang XJ; Zhao XS
Zhonghua Xue Ye Xue Za Zhi; 2023 Dec; 44(12):1010-1015. PubMed ID: 38503524
[No Abstract] [Full Text] [Related]
3. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
Abla O; Ries RE; Triche T; Gerbing RB; Hirsch B; Raimondi S; Cooper T; Farrar JE; Buteyn N; Harmon LM; Wen H; Deshpande AJ; Kolb EA; Gamis AS; Aplenc R; Alonzo T; Meshinchi S
Blood Adv; 2024 Apr; 8(8):2005-2017. PubMed ID: 38306602
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4. UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia.
Kaburagi T; Shiba N; Yamato G; Yoshida K; Tabuchi K; Ohki K; Ishikita E; Hara Y; Shiraishi Y; Kawasaki H; Sotomatsu M; Takizawa T; Taki T; Kiyokawa N; Tomizawa D; Horibe K; Miyano S; Taga T; Adachi S; Ogawa S; Hayashi Y
Genes Chromosomes Cancer; 2023 Apr; 62(4):202-209. PubMed ID: 36448876
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5. A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia.
Ren Z; Kim A; Huang YT; Pi WC; Gong W; Yu X; Qi J; Jin J; Cai L; Roeder RG; Chen WY; Wang GG
Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35217626
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6. Hyperleukocytosis predicts inferior clinical outcome in pediatric acute myeloid leukemia.
Xu LH; Wang JW; Wang Y; Yang FY
Hematology; 2020 Dec; 25(1):507-514. PubMed ID: 33317436
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7. CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J; Barbosa IAM; Eder T; Brandstoetter T; Schmidt L; Maurer B; Troester S; Pham HTT; Sagarajit M; Ebner J; Manhart G; Aslan E; Terlecki-Zaniewicz S; Van der Veen C; Hoermann G; Duployez N; Petit A; Lapillonne H; Puissant A; Itzykson R; Moriggl R; Heuser M; Meisel R; Valent P; Sexl V; Zuber J; Grebien F
Blood; 2020 Jul; 136(4):387-400. PubMed ID: 32344427
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8. Successful treatment of acute myeloid leukemia co-expressing NUP98/nsd1 and FLT3/ITD with preemptive donor lymphocyte infusions.
Mitani Y; Hiwatari M; Seki M; Hangai M; Takita J
Int J Hematol; 2019 Oct; 110(4):512-516. PubMed ID: 31134509
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9. Clinical and biological features of paediatric acute myeloid leukaemia (AML) with primary induction failure in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study.
Miyamura T; Moritake H; Nakayama H; Tanaka S; Tomizawa D; Shiba N; Saito AM; Tawa A; Shimada A; Iwamoto S; Hayashi Y; Koike T; Horibe K; Manabe A; Mizutani S; Taga T; Adachi S
Br J Haematol; 2019 Apr; 185(2):284-288. PubMed ID: 30784060
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10. Integrated Analysis of Genetic Abnormalities of the Histone Lysine Methyltransferases in Prostate Cancer.
Zhang Y; Yan L; Yao W; Chen K; Xu H; Ye Z
Med Sci Monit; 2019 Jan; 25():193-239. PubMed ID: 30616239
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11. Dasatinib and navitoclax act synergistically to target NUP98-nsd1
Kivioja JL; Thanasopoulou A; Kumar A; Kontro M; Yadav B; Majumder MM; Javarappa KK; Eldfors S; Schwaller J; Porkka K; Heckman CA
Leukemia; 2019 Jun; 33(6):1360-1372. PubMed ID: 30568173
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12. [Molecular Characteristics and Clinical Features of Adults with
Lun Y; Huang JC; Long D; Wang FF; Dai Y; Yang Y; Zhao TT; Li Q; Wu Y
Sichuan Da Xue Xue Bao Yi Xue Ban; 2018 Jul; 49(4):575-581. PubMed ID: 30378313
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13. Risk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study.
Shimada A; Iijima-Yamashita Y; Tawa A; Tomizawa D; Yamada M; Norio S; Watanabe T; Taga T; Iwamoto S; Terui K; Moritake H; Kinoshita A; Takahashi H; Nakayama H; Koh K; Goto H; Kosaka Y; Saito AM; Kiyokawa N; Horibe K; Hara Y; Oki K; Hayashi Y; Tanaka S; Adachi S
Int J Hematol; 2018 May; 107(5):586-595. PubMed ID: 29330746
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14. Chimeric NUP98-nsd1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia.
Kivioja JL; Lopez Martí JM; Kumar A; Kontro M; Edgren H; Parsons A; Lundán T; Wolf M; Porkka K; Heckman CA
Leuk Lymphoma; 2018 Mar; 59(3):725-732. PubMed ID: 28776436
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15. Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia.
Yamato G; Yamaguchi H; Handa H; Shiba N; Kawamura M; Wakita S; Inokuchi K; Hara Y; Ohki K; Okubo J; Park MJ; Sotomatsu M; Arakawa H; Hayashi Y
Genes Chromosomes Cancer; 2017 Nov; 56(11):800-809. PubMed ID: 28710806
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16. NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.
Struski S; Lagarde S; Bories P; Puiseux C; Prade N; Cuccuini W; Pages MP; Bidet A; Gervais C; Lafage-Pochitaloff M; Roche-Lestienne C; Barin C; Penther D; Nadal N; Radford-Weiss I; Collonge-Rame MA; Gaillard B; Mugneret F; Lefebvre C; Bart-Delabesse E; Petit A; Leverger G; Broccardo C; Luquet I; Pasquet M; Delabesse E
Leukemia; 2017 Mar; 31(3):565-572. PubMed ID: 27694926
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17. Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.
Garg M; Nagata Y; Kanojia D; Mayakonda A; Yoshida K; Haridas Keloth S; Zang ZJ; Okuno Y; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Ding LW; Alpermann T; Sun QY; Lin DC; Chien W; Madan V; Liu LZ; Tan KT; Sampath A; Venkatesan S; Inokuchi K; Wakita S; Yamaguchi H; Chng WJ; Kham SK; Yeoh AE; Sanada M; Schiller J; Kreuzer KA; Kornblau SM; Kantarjian HM; Haferlach T; Lill M; Kuo MC; Shih LY; Blau IW; Blau O; Yang H; Ogawa S; Koeffler HP
Blood; 2015 Nov; 126(22):2491-501. PubMed ID: 26438511
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18. Potent co-operation between the NUP98-nsd1 fusion and the FLT3-ITD mutation in acute myeloid leukemia induction.
Thanasopoulou A; Tzankov A; Schwaller J
Haematologica; 2014 Sep; 99(9):1465-71. PubMed ID: 24951466
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19. NUP98-nsd1 fusion in association with FLT3-ITD mutation identifies a prognostically relevant subgroup of pediatric acute myeloid leukemia patients suitable for monitoring by real time quantitative PCR.
Akiki S; Dyer SA; Grimwade D; Ivey A; Abou-Zeid N; Borrow J; Jeffries S; Caddick J; Newell H; Begum S; Tawana K; Mason J; Velangi M; Griffiths M
Genes Chromosomes Cancer; 2013 Nov; 52(11):1053-64. PubMed ID: 23999921
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20. NUP98-nsd1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia.
Shiba N; Ichikawa H; Taki T; Park MJ; Jo A; Mitani S; Kobayashi T; Shimada A; Sotomatsu M; Arakawa H; Adachi S; Tawa A; Horibe K; Tsuchida M; Hanada R; Tsukimoto I; Hayashi Y
Genes Chromosomes Cancer; 2013 Jul; 52(7):683-93. PubMed ID: 23630019
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