BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NT5C2, ENSG00000076685, 22978, P49902, PNT5, NT5B, GMP, cN-II
259 results:

  • 1. Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
    Dong H; He X; Zhang L; Chen W; Lin YC; Liu SB; Wang H; Nguyen LXT; Li M; Zhu Y; Zhao D; Ghoda L; Serody J; Vincent B; Luznik L; Gojo I; Zeidner J; Su R; Chen J; Sharma R; Pirrotte P; Wu X; Hu W; Han W; Shen B; Kuo YH; Jin J; Salhotra A; Wang J; Marcucci G; Luo YL; Li L
    Nat Cancer; 2024 Apr; 5(4):601-624. PubMed ID: 38413714
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Manufacturing of primary CAR-NK cells in an automated system for the treatment of acute myeloid leukemia.
    Albinger N; Müller S; Kostyra J; Kuska J; Mertlitz S; Penack O; Zhang C; Möker N; Ullrich E
    Bone Marrow Transplant; 2024 Apr; 59(4):489-495. PubMed ID: 38253870
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.
    Zhao M; Wang T; Gleber-Netto FO; Chen Z; McGrail DJ; Gomez JA; Ju W; Gadhikar MA; Ma W; Shen L; Wang Q; Tang X; Pathak S; Raso MG; Burks JK; Lin SY; Wang J; Multani AS; Pickering CR; Chen J; Myers JN; Zhou G
    Nat Commun; 2024 Jan; 15(1):180. PubMed ID: 38167338
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-AF9 leukemia.
    Li Y; Seet CS; Mack R; Joshi K; Runde AP; Hagen PA; Barton K; Breslin P; Kini A; Ji HL; Zhang J
    Stem Cell Reports; 2024 Jan; 19(1):100-111. PubMed ID: 38101400
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study.
    Zhang Y; Patel RP; Kim KH; Cho H; Jo JC; Jeong SH; Oh SY; Choi YS; Kim SH; Lee JH; Angelos M; Guruprasad P; Cohen I; Ugwuanyi O; Lee YG; Pajarillo R; Cho JH; Carturan A; Paruzzo L; Ghilardi G; Wang M; Kim S; Kim SM; Lee HJ; Park JH; Cui L; Lee TB; Hwang IS; Lee YH; Lee YJ; Porazzi P; Liu D; Lee Y; Kim JH; Lee JS; Yoon DH; Chung J; Ruella M
    Mol Cancer; 2023 Dec; 22(1):200. PubMed ID: 38066564
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. BloodChIP Xtra: an expanded database of comparative genome-wide transcription factor binding and gene-expression profiles in healthy human stem/progenitor subsets and leukemic cells.
    Thoms JAI; Koch FC; Raei A; Subramanian S; Wong JWH; Vafaee F; Pimanda JE
    Nucleic Acids Res; 2024 Jan; 52(D1):D1131-D1137. PubMed ID: 37870453
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Identification of Cell Type-Specific Effects of
    Bae SG; Kim HJ; Kim MY; Kim DDH; Shin SI; Ahn JS; Park J
    Mol Cells; 2023 Oct; 46(10):611-626. PubMed ID: 37853686
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Translational development of a novel BAFF-R CAR-T therapy targeting B-cell lymphoid malignancies.
    Luo Y; Qie Y; Gadd ME; Manna A; Rivera-Valentin R; To T; Li S; Yassine F; Murthy HS; Dronca R; Kharfan-Dabaja MA; Qin H
    Cancer Immunol Immunother; 2023 Dec; 72(12):4031-4047. PubMed ID: 37814001
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
    Eifert T; Hsu CJ; Becker AL; Graessle S; Horne A; Bemmann F; Zhang Q; Heuser M; Vasioukhin V; Scholl S; Hochhaus A; Siegerist F; Endlich N; Bullinger L; Lane SW; Haas S; Schnoeder TM; Heidel FH
    Leukemia; 2023 Oct; 37(10):2027-2035. PubMed ID: 37587260
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Good manufacturing practice production of CD34
    de Jonge PKJD; van Hauten PMM; Janssen LD; de Goede AL; Berrien-Elliott MM; van der Meer JMR; Mousset CM; Roeven MWH; Foster M; Blijlevens N; Hobo W; Fehniger TA; Jansen JH; Schaap NPM; Dolstra H
    Cancer Immunol Immunother; 2023 Oct; 72(10):3323-3335. PubMed ID: 37477653
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Integrated genomic and single-cell transcriptomic analyses reveal clonal evolution and immune signature in donor cell leukemia after haploidentical allogeneic hematopoietic stem cell transplantation.
    Chen H; Zhao X; Pan W; Xiao H
    Leuk Lymphoma; 2023 Oct; 64(10):1681-1688. PubMed ID: 37424322
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Elucidating the cell metabolic heterogeneity during hematopoietic lineage differentiation based on Met-Flow.
    Liang H; Zhang S; Ma Y; Wang H; Cao Z; Shi R; Kong X; Zhang Q; Zhou Y
    Int Immunopharmacol; 2023 Aug; 121():110443. PubMed ID: 37311353
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Cellular Composition and 5hmC Signature Predict the Treatment Response of AML Patients to Azacitidine Combined with Chemotherapy.
    Liang G; Wang L; You Q; Cahill K; Chen C; Zhang W; Fulton N; Stock W; Odenike O; He C; Han D
    Adv Sci (Weinh); 2023 Aug; 10(23):e2300445. PubMed ID: 37271891
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Single-cell resolution reveals RalA GTPase expanding hematopoietic stem cells and facilitating of BCR-ABL1-driven leukemogenesis in a CRISPR/Cas9 gene editing mouse model.
    Yin Z; Su R; Ge L; Wang X; Yang J; Huang G; Li C; Liu Y; Zhang K; Deng L; Fei J
    Int J Biol Sci; 2023; 19(4):1211-1227. PubMed ID: 36923939
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CAR-T cells targeting IL-1RAP produced in a closed semiautomatic system are ready for the first phase I clinical investigation in humans.
    Nicod C; da Rocha MN; Warda W; Roussel X; Haderbache R; Seffar E; Trad R; Bouquet L; Goncalves M; Bosdure L; Laude MC; Guiot M; Ferrand C; Deschamps M
    Curr Res Transl Med; 2023; 71(2):103385. PubMed ID: 36773434
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. CRISPR/Cas9-Mediated Induction of Relapse-Specific
    Nguyen TTT; Tanaka Y; Sanada M; Hosaka M; Tamai M; Kagami K; Komatsu C; Somazu S; Harama D; Kasai S; Watanabe A; Akahane K; Goi K; Inukai T
    Mol Pharmacol; 2023 Apr; 103(4):199-210. PubMed ID: 36669880
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. CLIC-01: Manufacture and distribution of non-cryopreserved CAR-T cells for patients with CD19 positive hematologic malignancies.
    Kekre N; Hay KA; Webb JR; Mallick R; Balasundaram M; Sigrist MK; Clement AM; Nielsen JS; Quizi J; Yung E; Brown SD; Dreolini L; Waller DD; Smazynski J; Gierc NS; Loveless BC; Clark K; Dyer T; Hogg R; McCormick L; Gignac M; Bell S; Chapman DM; Bond D; Yong S; Fung R; Lockyer HM; Hodgson V; Murphy C; Subramanian A; Wiebe E; Yoganathan P; Medynski L; Vaillan DC; Black A; McDiarmid S; Kennah M; Hamelin L; Song K; Narayanan S; Rodrigo JA; Dupont S; Hawrysh T; Presseau J; Thavorn K; Lalu MM; Fergusson DA; Bell JC; Atkins H; Nelson BH; Holt RA
    Front Immunol; 2022; 13():1074740. PubMed ID: 36601119
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Integrating RNA-seq and scRNA-seq to explore the biological significance of NAD + metabolism-related genes in the initial diagnosis and relapse of childhood B-cell acute lymphoblastic leukemia.
    Lin C; Xu JQ; Zhong GC; Chen H; Xue HM; Yang M; Chen C
    Front Immunol; 2022; 13():1043111. PubMed ID: 36439178
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD36.
    Nishinaka T; Hatipoglu OF; Wake H; Watanabe M; Toyomura T; Mori S; Nishibori M; Takahashi H
    Life Sci; 2022 Dec; 310():121116. PubMed ID: 36302498
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. 5'-nucleotidase, cytosolic II genotype, and clinical outcome in patients with acute myeloid leukemia with intermediate-risk cytogenetics.
    Díaz-Santa J; Rodríguez-Romanos R; Coll R; Osca G; Pratcorona M; González-Bártulos M; Garrido A; Angona A; Talarn C; Tormo M; Arnan M; Vives S; Salamero O; Tuset E; Lloveras N; Díez I; Zamora L; Bargay J; Sampol A; Cruz D; Vila J; Sitges M; Garcia A; Vall-Llovera F; Esteve J; Sierra J; Gallardo D;
    Eur J Haematol; 2022 Dec; 109(6):755-764. PubMed ID: 36063368
    [TBL] [Abstract] [Full Text] [Related]  


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