BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND NTRK1, ENSG00000198400, 4914, P04629, TRK1, MTC, DKFZp781I14186, p140-TrkA, TRKA, TRK
106 results:

  • 1. Analysis of CD74 Occurrence in Oncogenic Fusion Proteins.
    Vargas J; Pantouris G
    Int J Mol Sci; 2023 Nov; 24(21):. PubMed ID: 37958963
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. RBFOX2 recognizes N
    Dou X; Xiao Y; Shen C; Wang K; Wu T; Liu C; Li Y; Yu X; Liu J; Dai Q; Pajdzik K; Ye C; Ge R; Gao B; Yu J; Sun S; Chen M; Chen J; He C
    Nat Cell Biol; 2023 Sep; 25(9):1359-1368. PubMed ID: 37640841
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas.
    Cleverley TL; Peddineni S; Guarner J; Cingolani F; Garcia PK; Koehler H; Mocarski ES; Kalman D
    PLoS Pathog; 2023 May; 19(5):e1011387. PubMed ID: 37200402
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid leukemia.
    Sun Y; Xue Y; Liu H; Mu S; Sun P; Sun Y; Wang L; Wang H; Wang J; Wu T; Yin W; Qin Q; Sun Y; Yang H; Zhao D; Cheng M
    J Med Chem; 2023 Feb; 66(4):2396-2421. PubMed ID: 36734825
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Counteracting Immunosuppression in the Tumor Microenvironment by Oncolytic Newcastle Disease Virus and Cellular Immunotherapy.
    Schirrmacher V; van Gool S; Stuecker W
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361831
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Discovery of a benzimidazole-based dual FLT3/trka inhibitor targeting acute myeloid leukemia.
    Dokla EME; Abdel-Aziz AK; Milik SN; McPhillie MJ; Minucci S; Abouzid KAM
    Bioorg Med Chem; 2022 Feb; 56():116596. PubMed ID: 35033885
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Discovery of clinically relevant fusions in pediatric cancer.
    LaHaye S; Fitch JR; Voytovich KJ; Herman AC; Kelly BJ; Lammi GE; Arbesfeld JA; Wijeratne S; Franklin SJ; Schieffer KM; Bir N; McGrath SD; Miller AR; Wetzel A; Miller KE; Bedrosian TA; Leraas K; Varga EA; Lee K; Gupta A; Setty B; Boué DR; Leonard JR; Finlay JL; Abdelbaki MS; Osorio DS; Koo SC; Koboldt DC; Wagner AH; Eisfeld AK; Mrózek K; Magrini V; Cottrell CE; Mardis ER; Wilson RK; White P
    BMC Genomics; 2021 Dec; 22(1):872. PubMed ID: 34863095
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Second Report of
    Hughes CE; Correa H; Benedetti DJ; Smith B; Sumegi J; Bridge J
    Pediatr Dev Pathol; 2021; 24(6):554-558. PubMed ID: 34120511
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Novel risk factors for glucarpidase use in pediatric acute lymphoblastic leukemia: Hispanic ethnicity, age, and the ABCC4 gene.
    Zobeck MC; Bernhardt MB; Kamdar KY; Rabin KR; Lupo PJ; Scheurer ME
    Pediatr Blood Cancer; 2021 Aug; 68(8):e29036. PubMed ID: 33788417
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeted locus amplification to detect molecular markers in mantle cell and follicular lymphoma.
    Genuardi E; Klous P; Mantoan B; Drandi D; Ferrante M; Cavallo F; Alessandria B; Dogliotti I; Grimaldi D; Ragaini S; Clerico M; Lo Schirico M; Saraci E; Yilmaz M; Zaccaria GM; Cortelazzo S; Vitolo U; Luminari S; Federico M; Boccadoro M; van Min M; Splinter E; Ladetto M; Ferrero S
    Hematol Oncol; 2021 Aug; 39(3):293-303. PubMed ID: 33742718
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Pharmacokinetics and safety of pegylated recombinant human granulocyte colony-stimulating factor in children with acute leukaemia.
    Liu XT; Zhao YX; Jia GW; Yang F; Zhang CZ; Han B; Dai JH; Han YQ; Tang BH; Yang XM; Shi HY; Zhou Y; Sui ZG; Chen JZ; van den Anker JN; Zhao W
    Br J Clin Pharmacol; 2021 Aug; 87(8):3292-3300. PubMed ID: 33506975
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of trka independently of its demethylase activity in chronic myelogenous leukemia.
    Zhang C; Shen L; Zhu Y; Xu R; Deng Z; Liu X; Ding Y; Wang C; Shi Y; Bei L; Wei D; Thorne RF; Zhang XD; Yu L; Chen S
    Theranostics; 2021; 11(6):2691-2705. PubMed ID: 33456567
    [No Abstract]    [Full Text] [Related]  

  • 13. Breast metastasis from medullary carcinoma of thyroid: A case report with literature view.
    Mukhtar R; Hussain M; Mukhtar MA; Ali SM
    J Pak Med Assoc; 2020 Nov; 70(11):2051-2053. PubMed ID: 33341859
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Infantile fibrosarcoma with TPM3-ntrk1 fusion in a boy with Bloom syndrome.
    Huson SM; Staab T; Pereira M; Ward H; Paredes R; Evans DG; Baumhoer D; O'Sullivan J; Cheesman E; Schindler D; Meyer S
    Fam Cancer; 2022 Jan; 21(1):85-90. PubMed ID: 33219493
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Discovery and characterization of targetable Ntrk point mutations in hematologic neoplasms.
    Joshi SK; Qian K; Bisson WH; Watanabe-Smith K; Huang A; Bottomly D; Traer E; Tyner JW; McWeeney SK; Davare MA; Druker BJ; Tognon CE
    Blood; 2020 Jun; 135(24):2159-2170. PubMed ID: 32315394
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Clinical response to larotrectinib in adult Philadelphia chromosome-like ALL with cryptic ETV6-Ntrk3 rearrangement.
    Nardi V; Ku N; Frigault MJ; Dubuc AM; Tsai HK; Amrein PC; Hobbs GS; Brunner AM; Narayan R; Burke ME; Foster J; Dal Cin P; Maus MV; Fathi AT; Hock H
    Blood Adv; 2020 Jan; 4(1):106-111. PubMed ID: 31905241
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update.
    Roskoski R
    Pharmacol Res; 2020 Feb; 152():104609. PubMed ID: 31862477
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Larotrectinib in trk fusion-positive pediatric B-cell acute lymphoblastic leukemia.
    Schewe DM; Lenk L; Vogiatzi F; Winterberg D; Rademacher AV; Buchmann S; Henry D; Bergmann AK; Cario G; Cox MC
    Blood Adv; 2019 Nov; 3(22):3499-3502. PubMed ID: 31725893
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Revisiting Ntrks as an emerging oncogene in hematological malignancies.
    Joshi SK; Davare MA; Druker BJ; Tognon CE
    Leukemia; 2019 Nov; 33(11):2563-2574. PubMed ID: 31551508
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells.
    Nechiporuk T; Kurtz SE; Nikolova O; Liu T; Jones CL; D'Alessandro A; Culp-Hill R; d'Almeida A; Joshi SK; Rosenberg M; Tognon CE; Danilov AV; Druker BJ; Chang BH; McWeeney SK; Tyner JW
    Cancer Discov; 2019 Jul; 9(7):910-925. PubMed ID: 31048320
    [TBL] [Abstract] [Full Text] [Related]  


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