Terms: = Leukemia AND NTRK1, ENSG00000198400, 4914, P04629, TRK1, MTC, DKFZp781I14186, p140-TrkA, TRKA, TRK AND Treatment
33 results:
1. The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas.
Cleverley TL; Peddineni S; Guarner J; Cingolani F; Garcia PK; Koehler H; Mocarski ES; Kalman D
PLoS Pathog; 2023 May; 19(5):e1011387. PubMed ID: 37200402
[TBL] [Abstract] [Full Text] [Related]
2. Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the treatment of Chronic Myeloid leukemia.
Sun Y; Xue Y; Liu H; Mu S; Sun P; Sun Y; Wang L; Wang H; Wang J; Wu T; Yin W; Qin Q; Sun Y; Yang H; Zhao D; Cheng M
J Med Chem; 2023 Feb; 66(4):2396-2421. PubMed ID: 36734825
[TBL] [Abstract] [Full Text] [Related]
3. Counteracting Immunosuppression in the Tumor Microenvironment by Oncolytic Newcastle Disease Virus and Cellular Immunotherapy.
Schirrmacher V; van Gool S; Stuecker W
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361831
[TBL] [Abstract] [Full Text] [Related]
4. Pharmacokinetics and safety of pegylated recombinant human granulocyte colony-stimulating factor in children with acute leukaemia.
Liu XT; Zhao YX; Jia GW; Yang F; Zhang CZ; Han B; Dai JH; Han YQ; Tang BH; Yang XM; Shi HY; Zhou Y; Sui ZG; Chen JZ; van den Anker JN; Zhao W
Br J Clin Pharmacol; 2021 Aug; 87(8):3292-3300. PubMed ID: 33506975
[TBL] [Abstract] [Full Text] [Related]
5. Breast metastasis from medullary carcinoma of thyroid: A case report with literature view.
Mukhtar R; Hussain M; Mukhtar MA; Ali SM
J Pak Med Assoc; 2020 Nov; 70(11):2051-2053. PubMed ID: 33341859
[TBL] [Abstract] [Full Text] [Related]
6. Infantile fibrosarcoma with TPM3-ntrk1 fusion in a boy with Bloom syndrome.
Huson SM; Staab T; Pereira M; Ward H; Paredes R; Evans DG; Baumhoer D; O'Sullivan J; Cheesman E; Schindler D; Meyer S
Fam Cancer; 2022 Jan; 21(1):85-90. PubMed ID: 33219493
[TBL] [Abstract] [Full Text] [Related]
7. Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update.
Roskoski R
Pharmacol Res; 2020 Feb; 152():104609. PubMed ID: 31862477
[TBL] [Abstract] [Full Text] [Related]
8. Larotrectinib in trk fusion-positive pediatric B-cell acute lymphoblastic leukemia.
Schewe DM; Lenk L; Vogiatzi F; Winterberg D; Rademacher AV; Buchmann S; Henry D; Bergmann AK; Cario G; Cox MC
Blood Adv; 2019 Nov; 3(22):3499-3502. PubMed ID: 31725893
[TBL] [Abstract] [Full Text] [Related]
9. The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells.
Nechiporuk T; Kurtz SE; Nikolova O; Liu T; Jones CL; D'Alessandro A; Culp-Hill R; d'Almeida A; Joshi SK; Rosenberg M; Tognon CE; Danilov AV; Druker BJ; Chang BH; McWeeney SK; Tyner JW
Cancer Discov; 2019 Jul; 9(7):910-925. PubMed ID: 31048320
[TBL] [Abstract] [Full Text] [Related]
10. Identification of a secondary
Pendrick DM; Oberg JA; Hsiao SJ; Chung WK; Koval C; Sireci A; Kuo JH; Satwani P; Glasser CL; Sulis ML; Mansukhani MM; Glade Bender JL
Cold Spring Harb Mol Case Stud; 2019 Apr; 5(2):. PubMed ID: 30936199
[TBL] [Abstract] [Full Text] [Related]
11. Comparison of the Kinase Profile of Midostaurin (Rydapt) with That of Its Predominant Metabolites and the Potential Relevance of Some Newly Identified Targets to leukemia Therapy.
Manley PW; Caravatti G; Furet P; Roesel J; Tran P; Wagner T; Wartmann M
Biochemistry; 2018 Sep; 57(38):5576-5590. PubMed ID: 30148617
[TBL] [Abstract] [Full Text] [Related]
12. Larotrectinib (LOXO-101).
Berger S; Martens UM; Bochum S
Recent Results Cancer Res; 2018; 211():141-151. PubMed ID: 30069765
[TBL] [Abstract] [Full Text] [Related]
13. Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases.
Hilberg F; Tontsch-Grunt U; Baum A; Le AT; Doebele RC; Lieb S; Gianni D; Voss T; Garin-Chesa P; Haslinger C; Kraut N
J Pharmacol Exp Ther; 2018 Mar; 364(3):494-503. PubMed ID: 29263244
[TBL] [Abstract] [Full Text] [Related]
14. Antitumor Activity of Entrectinib, a Pan-trk, ROS1, and ALK Inhibitor, in
Smith KM; Fagan PC; Pomari E; Germano G; Frasson C; Walsh C; Silverman I; Bonvini P; Li G
Mol Cancer Ther; 2018 Feb; 17(2):455-463. PubMed ID: 29237803
[TBL] [Abstract] [Full Text] [Related]
15. Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms.
Diamond EL; Durham BH; Haroche J; Yao Z; Ma J; Parikh SA; Wang Z; Choi J; Kim E; Cohen-Aubart F; Lee SC; Gao Y; Micol JB; Campbell P; Walsh MP; Sylvester B; Dolgalev I; Aminova O; Heguy A; Zappile P; Nakitandwe J; Ganzel C; Dalton JD; Ellison DW; Estrada-Veras J; Lacouture M; Gahl WA; Stephens PJ; Miller VA; Ross JS; Ali SM; Briggs SR; Fasan O; Block J; Héritier S; Donadieu J; Solit DB; Hyman DM; Baselga J; Janku F; Taylor BS; Park CY; Amoura Z; Dogan A; Emile JF; Rosen N; Gruber TA; Abdel-Wahab O
Cancer Discov; 2016 Feb; 6(2):154-65. PubMed ID: 26566875
[TBL] [Abstract] [Full Text] [Related]
16. Elevated trka receptor expression is associated with all-trans retinoic acid-induced neuroblastoma differentiation.
Gao Q; Chen CF; Dong Q; Hou L; Chen X; Zhi YL; Li X; Lu HT; Zhang HY
Genet Mol Res; 2015 Oct; 14(4):13195-202. PubMed ID: 26535632
[TBL] [Abstract] [Full Text] [Related]
17. Tyrosine kinase inhibitors as a first-line treatment in patients with newly diagnosed chronic myeloid leukemia in chronic phase: A mixed-treatment comparison.
Firwana B; Sonbol MB; Diab M; Raza S; Hasan R; Yousef I; Zarzour A; Garipalli A; Doll D; Murad MH; Al-Kali A
Int J Cancer; 2016 Mar; 138(6):1545-53. PubMed ID: 26455714
[TBL] [Abstract] [Full Text] [Related]
18. Control of relapsed or refractory acute myeloid leukemia by clofarabine in preparation for allogeneic stem cell transplant.
Loeffler C; Kapp M; Grigoleit GU; Mielke S; Loeffler J; Heuschmann PU; Malzahn U; Hupp E; Einsele H; Stuhler G
Leuk Lymphoma; 2015; 56(12):3365-9. PubMed ID: 26014275
[TBL] [Abstract] [Full Text] [Related]
19. Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase.
Mologni L; Redaelli S; Morandi A; Plaza-Menacho I; Gambacorti-Passerini C
Mol Cell Endocrinol; 2013 Sep; 377(1-2):1-6. PubMed ID: 23811235
[TBL] [Abstract] [Full Text] [Related]
20. Danusertib, an aurora kinase inhibitor.
Meulenbeld HJ; Mathijssen RH; Verweij J; de Wit R; de Jonge MJ
Expert Opin Investig Drugs; 2012 Mar; 21(3):383-93. PubMed ID: 22242557
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