Terms: = Leukemia AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Clinical Outcome
11 results:
1. Simvastatin potentiates the cell-killing activity of imatinib in imatinib-resistant chronic myeloid leukemia cells mainly through pi3k/AKT pathway attenuation and Myc downregulation.
Ding L; Chen Q; Chen K; Jiang Y; Li G; Chen Q; Bai D; Gao D; Deng M; Zhang H; Xu B
Eur J Pharmacol; 2021 Dec; 913():174633. PubMed ID: 34843676
[TBL] [Abstract] [Full Text] [Related]
2. The protein landscape of chronic lymphocytic leukemia.
Meier-Abt F; Lu J; Cannizzaro E; Pohly MF; Kummer S; Pfammatter S; Kunz L; Collins BC; Nadeu F; Lee KS; Xue P; Gwerder M; Roiss M; Hüllein J; Scheinost S; Dietrich S; Campo E; Huber W; Aebersold R; Zenz T
Blood; 2021 Dec; 138(24):2514-2525. PubMed ID: 34189564
[TBL] [Abstract] [Full Text] [Related]
3. Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy.
Estruch M; Reckzeh K; Vittori C; Centio A; Ali M; Engelhard S; Zhao L; Won KJ; Liu P; Porse BT; Theilgaard-Mönch K
Leukemia; 2021 Jul; 35(7):2030-2042. PubMed ID: 33299144
[TBL] [Abstract] [Full Text] [Related]
4. NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
Thomé CH; Ferreira GA; Pereira-Martins DA; Dos Santos GA; Ortiz CA; de Souza LEB; Sobral LM; Silva CLA; Scheucher PS; Gil CD; Leopoldino AM; Silveira DRA; Coelho-Silva JL; Traina F; Koury LC; Melo RAM; Bittencourt R; Pagnano K; Pasquini R; Nunes EC; Fagundes EM; Gloria ABF; Kerbauy FR; Chauffaille ML; Keating A; Tallman MS; Ribeiro RC; Dillon R; Ganser A; Löwenberg B; Valk P; Lo-Coco F; Sanz MA; Berliner N; Faça VM; Rego EM
Sci Rep; 2020 Jun; 10(1):10315. PubMed ID: 32587277
[TBL] [Abstract] [Full Text] [Related]
5. Targeting steroid resistance in T-cell acute lymphoblastic leukemia.
De Smedt R; Morscio J; Goossens S; Van Vlierberghe P
Blood Rev; 2019 Nov; 38():100591. PubMed ID: 31353059
[TBL] [Abstract] [Full Text] [Related]
6.
Zhou JD; Li XX; Zhang TJ; Xu ZJ; Zhang ZH; Gu Y; Wen XM; Zhang W; Ji RB; Deng ZQ; Lin J; Qian J
Aging (Albany NY); 2019 May; 11(10):3376-3391. PubMed ID: 31147526
[No Abstract] [Full Text] [Related]
7. Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML.
Saenz DT; Fiskus W; Manshouri T; Mill CP; Qian Y; Raina K; Rajapakshe K; Coarfa C; Soldi R; Bose P; Borthakur G; Kadia TM; Khoury JD; Masarova L; Nowak AJ; Sun B; Saenz DN; Kornblau SM; Horrigan S; Sharma S; Qiu P; Crews CM; Verstovsek S; Bhalla KN
Leukemia; 2019 Jun; 33(6):1373-1386. PubMed ID: 30575820
[TBL] [Abstract] [Full Text] [Related]
8. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic leukemia: A Genome Sequencing Study.
Li Y; Buijs-Gladdines JG; Canté-Barrett K; Stubbs AP; Vroegindeweij EM; Smits WK; van Marion R; Dinjens WN; Horstmann M; Kuiper RP; Buijsman RC; Zaman GJ; van der Spek PJ; Pieters R; Meijerink JP
PLoS Med; 2016 Dec; 13(12):e1002200. PubMed ID: 27997540
[TBL] [Abstract] [Full Text] [Related]
9. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.
Feng Y; Xu X; Zhang Y; Ding J; Wang Y; Zhang X; Wu Z; Kang L; Liang Y; Zhou L; Song S; Zhao K; Ye Q
Sci Rep; 2015 Mar; 5():9429. PubMed ID: 25800793
[TBL] [Abstract] [Full Text] [Related]
10. Molecular pathways: targeting phosphoinositide 3-kinase p110-delta in chronic lymphocytic leukemia.
Herman SE; Johnson AJ
Clin Cancer Res; 2012 Aug; 18(15):4013-8. PubMed ID: 22711705
[TBL] [Abstract] [Full Text] [Related]
11. Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and pi3kinase response profiles in human acute myelogenous leukemia.
Rosen DB; Putta S; Covey T; Huang YW; Nolan GP; Cesano A; Minden MD; Fantl WJ
PLoS One; 2010 Aug; 5(8):e12405. PubMed ID: 20811632
[TBL] [Abstract] [Full Text] [Related]
