BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND PIM1, PIM, 5292, ENSG00000137193, P11309 AND Prognosis
33 results:

  • 1. IGH 3'RR recombination uncovers a non-germinal center imprint and c-MYC-dependent IGH rearrangement in unmutated chronic lymphocytic leukemia.
    Al Jamal I; Parquet M; Guiyedi K; Aoufouchi S; Le Guillou M; Rizzo D; Pollet J; Dupont M; Boulin M; Faumont N; Boutouil H; Jardin F; Ruminy P; El Hamel C; Lerat J; Al Hamaoui S; Makdissy N; Feuillard J; Gachard N; Peron S
    Haematologica; 2024 Feb; 109(2):466-478. PubMed ID: 37496419
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Relationship between the transcriptional expression of pim1 and local control in patients with head and neck squamous cell carcinomas treated with radiotherapy.
    León X; García J; Pujol A; de Juan J; Vásquez R; Quer M; Camacho M
    Eur Arch Otorhinolaryngol; 2022 Jul; 279(7):3679-3684. PubMed ID: 34993612
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prognostic and immunomodulatory effects of pim1 in colorectal carcinoma.
    Zhou Y; Zhou Y; Liu S; Wang J; Ji R; Yan X
    J BUON; 2021; 26(2):513-520. PubMed ID: 34077000
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Effects of pim3 in prognosis of colon cancer.
    Zhou Y; Zhou YN; Liu SX; Wang J; Ji R; Yan X
    Clin Transl Oncol; 2021 Oct; 23(10):2163-2170. PubMed ID: 33928496
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Design and synthesis of a novel mitochondria-targeted osteosarcoma theranostic agent based on a pim1 kinase inhibitor.
    Yi X; Cao Z; Yuan Y; Li W; Cui X; Chen Z; Hu X; Yu A
    J Control Release; 2021 Apr; 332():434-447. PubMed ID: 33662457
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. New Quinoxaline Derivatives as Dual pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation.
    Oyallon B; Brachet-Botineau M; Logé C; Robert T; Bach S; Ibrahim S; Raoul W; Croix C; Berthelot P; Guillon J; Pinaud N; Gouilleux F; Viaud-Massuard MC; Denevault-Sabourin C
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33562106
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Resveratrol suppresses gastric cancer cell proliferation and survival through inhibition of pim-1 kinase activity.
    Kim S; Kim W; Kim DH; Jang JH; Kim SJ; Park SA; Hahn H; Han BW; Na HK; Chun KS; Choi BY; Surh YJ
    Arch Biochem Biophys; 2020 Aug; 689():108413. PubMed ID: 32473133
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. TAB3 upregulates pim1 expression by directly activating the TAK1-STAT3 complex to promote colorectal cancer growth.
    Li Q; Chen L; Luo C; ChenYan ; Ge J; Zhu Z; Wang K; Yu X; Lei J; Liu T; Peng X; Liu X; Yuan R
    Exp Cell Res; 2020 Jun; 391(1):111975. PubMed ID: 32229191
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia.
    Hu X; Chen F
    Hematology; 2019 Dec; 24(1):651-660. PubMed ID: 31533545
    [No Abstract]    [Full Text] [Related]  

  • 10. The upregulation of pim kinases is essential in coordinating the survival, proliferation, and migration of KIT D816V-mutated neoplastic mast cells.
    Park H; Kim D; Koh Y; Yoon SS
    Leuk Res; 2019 Aug; 83():106166. PubMed ID: 31203104
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic leukemia.
    Minieri V; De Dominici M; Porazzi P; Mariani SA; Spinelli O; Rambaldi A; Peterson LF; Porcu P; Nevalainen MT; Calabretta B
    Cancer Res; 2018 Oct; 78(20):5793-5807. PubMed ID: 30154155
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting pim1 and Disrupting the pim1/CXCR4 Interaction.
    Ye C; Zhang C; Huang H; Yang B; Xiao G; Kong D; Tian Q; Song Q; Song Y; Tan H; Wang Y; Zhou T; Zi X; Sun Y
    Cell Physiol Biochem; 2018; 48(3):1230-1244. PubMed ID: 30045021
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. pim-1 mRNA expression is a potential prognostic biomarker in acute myeloid leukemia.
    Cheng H; Huang C; Xu X; Hu X; Gong S; Tang G; Song X; Zhang W; Wang J; Chen L; Yang J
    J Transl Med; 2017 Aug; 15(1):179. PubMed ID: 28851457
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. pim-1 kinase inhibitor SMI-4a exerts antitumor effects in chronic myeloid leukemia cells by enhancing the activity of glycogen synthase kinase 3β.
    Fan RF; Lu Y; Fang ZG; Guo XY; Chen YX; Xu YC; Lei YM; Liu KF; Lin DJ; Liu LL; Liu XF
    Mol Med Rep; 2017 Oct; 16(4):4603-4612. PubMed ID: 28849186
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Expression and function of pim kinases in osteosarcoma.
    Mou S; Wang G; Ding D; Yu D; Pei Y; Teng S; Fu Q
    Int J Oncol; 2016 Nov; 49(5):2116-2126. PubMed ID: 27826617
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. pim1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
    Brasó-Maristany F; Filosto S; Catchpole S; Marlow R; Quist J; Francesch-Domenech E; Plumb DA; Zakka L; Gazinska P; Liccardi G; Meier P; Gris-Oliver A; Cheang MC; Perdrix-Rosell A; Shafat M; Noël E; Patel N; McEachern K; Scaltriti M; Castel P; Noor F; Buus R; Mathew S; Watkins J; Serra V; Marra P; Grigoriadis A; Tutt AN
    Nat Med; 2016 Nov; 22(11):1303-1313. PubMed ID: 27775704
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and pim1 by CDK6.
    Uras IZ; Walter GJ; Scheicher R; Bellutti F; Prchal-Murphy M; Tigan AS; Valent P; Heidel FH; Kubicek S; Scholl C; Fröhling S; Sexl V
    Blood; 2016 Jun; 127(23):2890-902. PubMed ID: 27099147
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A small-molecule inhibitor of pim kinases as a potential treatment for urothelial carcinomas.
    Foulks JM; Carpenter KJ; Luo B; Xu Y; Senina A; Nix R; Chan A; Clifford A; Wilkes M; Vollmer D; Brenning B; Merx S; Lai S; McCullar MV; Ho KK; Albertson DJ; Call LT; Bearss JJ; Tripp S; Liu T; Stephens BJ; Mollard A; Warner SL; Bearss DJ; Kanner SB
    Neoplasia; 2014 May; 16(5):403-12. PubMed ID: 24953177
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Novel myelofibrosis treatment strategies: potential partners for combination therapies.
    Stein BL; Swords R; Hochhaus A; Giles F
    Leukemia; 2014 Nov; 28(11):2139-47. PubMed ID: 24888274
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Expression of pim-1 in tumors, tumor stroma and tumor-adjacent mucosa co-determines the prognosis of colon cancer patients.
    Peng YH; Li JJ; Xie FW; Chen JF; Yu YH; Ouyang XN; Liang HJ
    PLoS One; 2013; 8(10):e76693. PubMed ID: 24116137
    [TBL] [Abstract] [Full Text] [Related]  


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