Terms: = Leukemia AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
52 results:
1. Advances in MDS/AML and inositide signalling.
De Stefano A; Marvi MV; Fazio A; McCubrey JA; Suh PG; Ratti S; Ramazzotti G; Manzoli L; Cocco L; Follo MY
Adv Biol Regul; 2023 Jan; 87():100955. PubMed ID: 36706610
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2. A frequent PLCγ1 mutation in adult T-cell leukemia/lymphoma determines functional properties of the malignant cells.
Prawiro C; Bunney TD; Kampyli C; Yaguchi H; Katan M; Bangham CRM
Biochim Biophys Acta Mol Basis Dis; 2023 Feb; 1869(2):166601. PubMed ID: 36442790
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3. TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.
Zhang H; Zhan Q; Wang X; Gao F; Yu J; Wang J; Fu W; Wang P; Wei X; Zhang L
Ann Hematol; 2022 Dec; 101(12):2583-2600. PubMed ID: 36181538
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4. The pyroptosis-related gene signature predicts prognosis and indicates the immune microenvironment status of chronic lymphocytic leukemia.
Sha Y; Jiang R; Miao Y; Qin S; Wu W; Xia Y; Wang L; Fan L; Jin H; Xu W; Li J; Zhu H
Front Immunol; 2022; 13():939978. PubMed ID: 36177050
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5. A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR Signaling.
Schultz A; Schnurra M; El-Bizri A; Woessner NM; Hartmann S; Hartig R; Minguet S; Schraven B; Simeoni L
Cells; 2022 Sep; 11(17):. PubMed ID: 36078131
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6. Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation.
Peiris MN; Meyer AN; Warda D; Campos AR; Donoghue DJ
Oncotarget; 2022; 13():659-676. PubMed ID: 35574218
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7. Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic leukemia.
Braun T; Stachelscheid J; Bley N; Oberbeck S; Otte M; Müller TA; Wahnschaffe L; Glaß M; Ommer K; Franitza M; Gathof B; Altmüller J; Hallek M; Auguin D; Hüttelmaier S; Schrader A; Herling M
Cancer Res; 2022 May; 82(9):1818-1831. PubMed ID: 35259248
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8. Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation.
Redondo Monte E; Leubolt G; Windisch R; Kerbs P; Dutta S; Landspersky T; Istvánffy R; Oostendorp RAJ; Chen-Wichmann L; Herold T; Cusan M; Schotta G; Wichmann C; Greif PA
Exp Hematol; 2022 Apr; 108():26-35. PubMed ID: 35181392
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9. A computational in silico approach to predict high-risk coding and non-coding SNPs of human plcg1 gene.
Khan SM; Faisal AM; Nila TA; Binti NN; Hosen MI; Shekhar HU
PLoS One; 2021; 16(11):e0260054. PubMed ID: 34793541
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10. plcg1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder TM; Schwarzer A; Jayavelu AK; Hsu CJ; Kirkpatrick J; Döhner K; Perner F; Eifert T; Huber N; Arreba-Tutusaus P; Dolnik A; Assi SA; Nafria M; Jiang L; Dai YT; Chen Z; Chen SJ; Kellaway SG; Ptasinska A; Ng ES; Stanley EG; Elefanty AG; Buschbeck M; Bierhoff H; Brodt S; Matziolis G; Fischer KD; Hochhaus A; Chen CW; Heidenreich O; Mann M; Lane SW; Bullinger L; Ori A; von Eyss B; Bonifer C; Heidel FH
Blood; 2022 Feb; 139(7):1080-1097. PubMed ID: 34695195
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11. Sensitization to Drug Treatment in Precursor B-Cell Acute Lymphoblastic leukemia Is Not Achieved by Stromal NF-κB Inhibition of Cell Adhesion but by Stromal PKC-Dependent Inhibition of ABC Transporters Activity.
Ruiz-Aparicio PF; Uribe GI; Linares-Ballesteros A; Vernot JP
Molecules; 2021 Sep; 26(17):. PubMed ID: 34500796
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12. Genetic profile of adult T-cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV-1 strains.
Sakihama S; Morichika K; Saito R; Miyara M; Miyagi T; Hayashi M; Uchihara J; Tomoyose T; Ohshiro K; Nakayama S; Nakachi S; Morishima S; Sakai K; Nishio K; Masuzaki H; Fukushima T; Karube K
Cancer Sci; 2021 Mar; 112(3):1300-1309. PubMed ID: 33426772
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13. RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma.
Uchida Y; Yoshimitsu M; Hachiman M; Kusano S; Arima N; Shima K; Hayashida M; Kamada Y; Nakamura D; Arai A; Tanaka Y; Hara H; Ishitsuka K
Eur J Haematol; 2021 Feb; 106(2):221-229. PubMed ID: 33098696
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14. Clinical application of genomic aberrations in adult T-cell leukemia/lymphoma.
Kataoka K; Koya J
J Clin Exp Hematop; 2020 Sep; 60(3):66-72. PubMed ID: 32779615
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15. Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions.
Yoshida N; Shigemori K; Donaldson N; Trevisani C; Cordero NA; Stevenson KE; Bu X; Arakawa F; Takeuchi M; Ohshima K; Yoda A; Ng SY; Weinstock DM
Blood; 2020 Apr; 135(17):1467-1471. PubMed ID: 31961925
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16. Advanced-stage mycosis fungoides: role of the signal transducer and activator of transcription 3, nuclear factor-κB and nuclear factor of activated T cells pathways.
Pérez C; Mondéjar R; García-Díaz N; Cereceda L; León A; Montes S; Durán Vian C; Pérez Paredes MG; González-Morán A; Alegre de Miguel V; Sanz Anquela JM; Frias J; Limeres MA; González LM; Martín Dávila F; Beltrán M; Mollejo M; Méndez JR; González MA; González García J; López R; Gómez A; Izquierdo F; Ramos R; Camacho C; Rodriguez-Pinilla SM; Martínez N; Vaqué JP; Ortiz-Romero PL; Piris MA
Br J Dermatol; 2020 Jan; 182(1):147-155. PubMed ID: 31049933
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17. Discovery of 7H-pyrrolo[2,3-d]pyrimidine derivatives as selective covalent irreversible inhibitors of interleukin-2-inducible T-cell kinase (Itk).
Tang G; Liu L; Wang X; Pan Z
Eur J Med Chem; 2019 Jul; 173():167-183. PubMed ID: 30999237
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18. Mutational Intratumor Heterogeneity is a Complex and Early Event in the Development of Adult T-cell leukemia/Lymphoma.
Farmanbar A; Firouzi S; Makałowski W; Kneller R; Iwanaga M; Utsunomiya A; Nakai K; Watanabe T
Neoplasia; 2018 Sep; 20(9):883-893. PubMed ID: 30032036
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19. Oncogenomic analysis identifies novel biomarkers for tumor stage mycosis fungoides.
Dong Z; Zhu X; Li Y; Gan L; Chen H; Zhang W; Sun J
Medicine (Baltimore); 2018 May; 97(21):e10871. PubMed ID: 29794791
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20. Genetic alterations in adult T-cell leukemia/lymphoma.
Kogure Y; Kataoka K
Cancer Sci; 2017 Sep; 108(9):1719-1725. PubMed ID: 28627735
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