Terms: = Leukemia AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148 AND Treatment
21 results:
1. TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.
Zhang H; Zhan Q; Wang X; Gao F; Yu J; Wang J; Fu W; Wang P; Wei X; Zhang L
Ann Hematol; 2022 Dec; 101(12):2583-2600. PubMed ID: 36181538
[TBL] [Abstract] [Full Text] [Related]
2. The pyroptosis-related gene signature predicts prognosis and indicates the immune microenvironment status of chronic lymphocytic leukemia.
Sha Y; Jiang R; Miao Y; Qin S; Wu W; Xia Y; Wang L; Fan L; Jin H; Xu W; Li J; Zhu H
Front Immunol; 2022; 13():939978. PubMed ID: 36177050
[TBL] [Abstract] [Full Text] [Related]
3. A computational in silico approach to predict high-risk coding and non-coding SNPs of human plcg1 gene.
Khan SM; Faisal AM; Nila TA; Binti NN; Hosen MI; Shekhar HU
PLoS One; 2021; 16(11):e0260054. PubMed ID: 34793541
[TBL] [Abstract] [Full Text] [Related]
4. Sensitization to Drug treatment in Precursor B-Cell Acute Lymphoblastic leukemia Is Not Achieved by Stromal NF-κB Inhibition of Cell Adhesion but by Stromal PKC-Dependent Inhibition of ABC Transporters Activity.
Ruiz-Aparicio PF; Uribe GI; Linares-Ballesteros A; Vernot JP
Molecules; 2021 Sep; 26(17):. PubMed ID: 34500796
[TBL] [Abstract] [Full Text] [Related]
5. Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions.
Yoshida N; Shigemori K; Donaldson N; Trevisani C; Cordero NA; Stevenson KE; Bu X; Arakawa F; Takeuchi M; Ohshima K; Yoda A; Ng SY; Weinstock DM
Blood; 2020 Apr; 135(17):1467-1471. PubMed ID: 31961925
[TBL] [Abstract] [Full Text] [Related]
6. Advanced-stage mycosis fungoides: role of the signal transducer and activator of transcription 3, nuclear factor-κB and nuclear factor of activated T cells pathways.
Pérez C; Mondéjar R; García-Díaz N; Cereceda L; León A; Montes S; Durán Vian C; Pérez Paredes MG; González-Morán A; Alegre de Miguel V; Sanz Anquela JM; Frias J; Limeres MA; González LM; Martín Dávila F; Beltrán M; Mollejo M; Méndez JR; González MA; González García J; López R; Gómez A; Izquierdo F; Ramos R; Camacho C; Rodriguez-Pinilla SM; Martínez N; Vaqué JP; Ortiz-Romero PL; Piris MA
Br J Dermatol; 2020 Jan; 182(1):147-155. PubMed ID: 31049933
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7. Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1-infected T cells.
Watanabe T
Blood; 2017 Mar; 129(9):1071-1081. PubMed ID: 28115366
[TBL] [Abstract] [Full Text] [Related]
8. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival.
Zhong W; Yi Q; Xu B; Li S; Wang T; Liu F; Zhu B; Hoffmann PR; Ji G; Lei P; Li G; Li J; Li J; Olkkonen VM; Yan D
Nat Commun; 2016 Sep; 7():12702. PubMed ID: 27581363
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9. Inositide-dependent signaling pathways as new therapeutic targets in myelodysplastic syndromes.
Mongiorgi S; Finelli C; Yang YR; Clissa C; McCubrey JA; Billi AM; Manzoli L; Suh PG; Cocco L; Follo MY
Expert Opin Ther Targets; 2016 Jun; 20(6):677-87. PubMed ID: 26610046
[TBL] [Abstract] [Full Text] [Related]
10. Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in Sézary syndrome.
Kiel MJ; Sahasrabuddhe AA; Rolland DCM; Velusamy T; Chung F; Schaller M; Bailey NG; Betz BL; Miranda RN; Porcu P; Byrd JC; Medeiros LJ; Kunkel SL; Bahler DW; Lim MS; Elenitoba-Johnson KSJ
Nat Commun; 2015 Sep; 6():8470. PubMed ID: 26415585
[TBL] [Abstract] [Full Text] [Related]
11. CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans.
Martinez-Torres AC; Quiney C; Attout T; Boullet H; Herbi L; Vela L; Barbier S; Chateau D; Chapiro E; Nguyen-Khac F; Davi F; Le Garff-Tavernier M; Moumné R; Sarfati M; Karoyan P; Merle-Béral H; Launay P; Susin SA
PLoS Med; 2015 Mar; 12(3):e1001796. PubMed ID: 25734483
[TBL] [Abstract] [Full Text] [Related]
12. Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients.
Follo MY; Mongiorgi S; Clissa C; Paolini S; Martinelli G; Martelli AM; Fioravanti G; Manzoli L; Finelli C; Cocco L
Leukemia; 2012 Dec; 26(12):2474-82. PubMed ID: 22596089
[TBL] [Abstract] [Full Text] [Related]
13. Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.
Markova B; Albers C; Breitenbuecher F; Melo JV; Brümmendorf TH; Heidel F; Lipka D; Duyster J; Huber C; Fischer T
Oncogene; 2010 Feb; 29(5):739-51. PubMed ID: 19881535
[TBL] [Abstract] [Full Text] [Related]
14. A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas.
Balasubramanian S; Ramos J; Luo W; Sirisawad M; Verner E; Buggy JJ
Leukemia; 2008 May; 22(5):1026-34. PubMed ID: 18256683
[TBL] [Abstract] [Full Text] [Related]
15. Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing plcgamma1- and Ca2+-dependent apoptosis.
Baumann S; Fas SC; Giaisi M; Müller WW; Merling A; Gülow K; Edler L; Krammer PH; Li-Weber M
Blood; 2008 Feb; 111(4):2354-63. PubMed ID: 18070986
[TBL] [Abstract] [Full Text] [Related]
16. PD98059 triggers G1 arrest and apoptosis in human leukemic U937 cells through downregulation of Akt signal pathway.
Moon DO; Park C; Heo MS; Park YM; Choi YH; Kim GY
Int Immunopharmacol; 2007 Jan; 7(1):36-45. PubMed ID: 17161815
[TBL] [Abstract] [Full Text] [Related]
17. Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells.
Srinivasan D; Plattner R
Cancer Res; 2006 Jun; 66(11):5648-55. PubMed ID: 16740702
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18. Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt.
Choi YJ; Park JW; Suh SI; Mun KC; Bae JH; Song DK; Kim SP; Kwon TK
Int J Oncol; 2002 Sep; 21(3):603-10. PubMed ID: 12168106
[TBL] [Abstract] [Full Text] [Related]
19. Failure to activate caspase 3 in phorbol ester-resistant leukemia cells is associated with resistance to apoptotic cell death.
Choi YJ; Park JW; Woo JH; Kim YH; Lee SH; Lee JM; Kwon TK
Cancer Lett; 2002 Aug; 182(2):183-91. PubMed ID: 12048164
[TBL] [Abstract] [Full Text] [Related]
20. Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells.
Park JW; Choi YJ; Jang MA; Baek SH; Lim JH; Passaniti T; Kwon TK
Biochem Biophys Res Commun; 2001 Aug; 286(4):726-34. PubMed ID: 11520058
[TBL] [Abstract] [Full Text] [Related]
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