BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND PRKAR1A, DKFZp779L0468, 5573, ENSG00000108946, PRKAR1, P10644, CNC1, PKR1, MGC17251, PPNAD1, TSE1, CNC, CAR AND Clinical Outcome
28 results:

  • 1. Treatment of adult ALL patients with third-generation CD19-directed car T cells: results of a pivotal trial.
    Schubert ML; Schmitt A; Hückelhoven-Krauss A; Neuber B; Kunz A; Waldhoff P; Vonficht D; Yousefian S; Jopp-Saile L; Wang L; Korell F; Keib A; Michels B; Haas D; Sauer T; Derigs P; Kulozik A; Kunz J; Pavel P; Laier S; Wuchter P; Schmier J; Bug G; Lang F; Gökbuget N; Casper J; Görner M; Finke J; Neubauer A; Ringhoffer M; Wolleschak D; Brüggemann M; Haas S; Ho AD; Müller-Tidow C; Dreger P; Schmitt M
    J Hematol Oncol; 2023 Jul; 16(1):79. PubMed ID: 37481608
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Culture expansion of car T cells results in aberrant DNA methylation that is associated with adverse clinical outcome.
    Salz L; Seitz A; Schäfer D; Franzen J; Holzer T; Garcia-Prieto CA; Bürger I; Hardt O; Esteller M; Wagner W
    Leukemia; 2023 Sep; 37(9):1868-1878. PubMed ID: 37452103
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Leukapheresis and Tisagenlecleucel Manufacturing outcomes in Patients Age <3 Years with Relapsed/Refractory Acute Lymphoblastic leukemia.
    Fong D; Tiwari R; Acker C; Clough L; Willert J
    Transplant Cell Ther; 2023 Sep; 29(9):579.e1-579.e10. PubMed ID: 37311511
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Characterization of the input material quality for the production of tisagenlecleucel by multiparameter flow cytometry and its relation to the clinical outcome.
    Štach M; Pytlík R; Šmilauerová K; Rychlá J; Mucha M; Musil J; Koladiya A; Nemec M; Petráčková M; Kaštánková I; Pecherková P; Šrámková L; Polgárová K; Trněný M; Lesný P; Vydra J; Otáhal P
    Pathol Oncol Res; 2023; 29():1610914. PubMed ID: 37151356
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Serpin B9 controls tumor cell killing by car T cells.
    Kimman T; Slomp A; Martens A; Grabherr S; Li S; van Diest E; Meeldijk J; Kuball J; Minnema MC; Eldering E; Bovenschen N; Sebestyén Z; Peperzak V
    J Immunother Cancer; 2023 Mar; 11(3):. PubMed ID: 36931661
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers.
    Jiménez-Reinoso A; Tirado N; Martinez-Moreno A; Díaz VM; García-Peydró M; Hangiu O; Díez-Alonso L; Albitre Á; Penela P; Toribio ML; Menéndez P; Álvarez-Vallina L; Sánchez Martínez D
    J Immunother Cancer; 2022 Dec; 10(12):. PubMed ID: 36564128
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Preliminary Report of the Academic car-T (ISIKOK-19) Cell clinical Trial in Turkey: Characterization of Product and outcomes of clinical Application.
    Erdoğan E; Yalçın K; Hemşinlioğlu C; Sezgin A; Seyis U; Kançağı DD; Taştan C; Yurtsever B; Turan RD; Çakırsoy D; Abanuz S; Sır Karakuş G; Elek M; Bekoz HS; Gemici Aİ; Sargın D; Arat M; Ferhanoğlu B; Pekgüç E; Örnek S; Büyüktaş D; Birgen N; Ratip S; Ovalı E
    Turk J Haematol; 2022 Aug; 39(3):206-210. PubMed ID: 35848614
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Antibody-based therapy for acute myeloid leukemia: a review of phase 2 and 3 trials.
    Thomas X; Elhamri M; Deloire A; Heiblig M
    Expert Opin Emerg Drugs; 2022 Jun; 27(2):169-185. PubMed ID: 35749672
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Fludarabine exposure predicts outcome after CD19 car T-cell therapy in children and young adults with acute leukemia.
    Dekker L; Calkoen FG; Jiang Y; Blok H; Veldkamp SR; De Koning C; Spoon M; Admiraal R; Hoogerbrugge P; Vormoor B; Vormoor HJ; Visscher H; Bierings M; Van Der Vlugt M; Van Tinteren H; Nijstad AL; Huitema ADR; Van Der Elst KCM; Pieters R; Lindemans CA; Nierkens S
    Blood Adv; 2022 Apr; 6(7):1969-1976. PubMed ID: 35134115
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. An epigenetic signature in CD19-car T cells predicts clinical outcome.
    Simonetta F; Bertoni F
    Trends Cancer; 2022 Feb; 8(2):81-82. PubMed ID: 34972674
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies.
    Garcia-Prieto CA; Villanueva L; Bueno-Costa A; Davalos V; González-Navarro EA; Juan M; Urbano-Ispizua Á; Delgado J; Ortiz-Maldonado V; Del Bufalo F; Locatelli F; Quintarelli C; Sinibaldi M; Soler M; Castro de Moura M; Ferrer G; Urdinguio RG; Fernandez AF; Fraga MF; Bar D; Meir A; Itzhaki O; Besser MJ; Avigdor A; Jacoby E; Esteller M
    J Natl Cancer Inst; 2022 Mar; 114(3):436-445. PubMed ID: 34581788
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Homogeneously high expression of CD32b makes it a potential target for car-T therapy for chronic lymphocytic leukemia.
    Wang G; Sun X; Zuo S; Li C; Niu Q; Xia Y; Meng Y; Liu M; Fang Z; Yang X; Jiang Y; Wang S; Cui H; Huang H; Jiang E; Zhou D; Deng Q; Pan J; Feng X
    J Hematol Oncol; 2021 Sep; 14(1):149. PubMed ID: 34530888
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Robust Antitumor Activity and Low Cytokine Production by Novel Humanized Anti-CD19 car T Cells.
    Dwivedi A; Karulkar A; Ghosh S; Srinivasan S; Kumbhar BV; Jaiswal AK; Kizhakeyil A; Asija S; Rafiq A; Kumar S; Nisar A; Patil DP; Poojary MV; Jain H; Banavali SD; Highfill SL; Stroncek DF; Shah NN; Fry TJ; Narula G; Purwar R
    Mol Cancer Ther; 2021 May; 20(5):846-858. PubMed ID: 33632869
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. BACH2-mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL.
    Zhang H; Zhang R; Zheng X; Sun M; Fan J; Fang C; Tian X; Zheng H
    Cancer Sci; 2021 Mar; 112(3):1235-1250. PubMed ID: 33393145
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. New monoclonal antibodies and tyrosine kinase inhibitors in B-cell acute lymphoblastic leukemia.
    Lanza F; Maffini E; Saraceni F; Massari E; Rondoni M; Daghia G; Olivieri A; Cerchione C; Martinelli G
    Minerva Med; 2020 Oct; 111(5):478-490. PubMed ID: 32955830
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. car T-cell therapy-related neurotoxicity in paediatric acute lymphocytic leukaemia.
    Tan AP
    Pediatr Blood Cancer; 2020 Nov; 67(11):e28635. PubMed ID: 32770654
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Dissecting factors influencing response to car T cell therapy in B lymphoid hematologic malignancies: from basic to practice.
    Wudhikarn K; Park JH
    Leuk Lymphoma; 2020 Oct; 61(10):2324-2334. PubMed ID: 32522059
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Combination Strategies for Immune-Checkpoint Blockade and Response Prediction by Artificial Intelligence.
    Huemer F; Leisch M; Geisberger R; Melchardt T; Rinnerthaler G; Zaborsky N; Greil R
    Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32325898
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Pharmacological targeting of immune checkpoint A2aR improves function of anti-CD19 car T cells in vitro.
    Fallah-Mehrjardi K; Mirzaei HR; Masoumi E; Jafarzadeh L; Rostamian H; Khakpoor-Koosheh M; Alishah K; Noorbakhsh F; Hadjati J
    Immunol Lett; 2020 Jul; 223():44-52. PubMed ID: 32289340
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Not So FASt: Tumor Cells Resisting Death Drive car T-cell Dysfunction.
    Green MR; Neelapu SS
    Cancer Discov; 2020 Apr; 10(4):492-494. PubMed ID: 32238396
    [TBL] [Abstract] [Full Text] [Related]  


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