Terms: = Leukemia AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602
37 results:
1. Sustained Suppression of Gorlin Syndrome-Associated Basal Cell Carcinomas with Vismodegib or Sonidegib: A Case Series.
Wescott R; Samlowski W
Curr Oncol; 2023 Oct; 30(10):9156-9167. PubMed ID: 37887561
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2. Prevalence of pathogenic variants in cancer-predisposing genes in second cancer after childhood solid cancers.
Yoshida M; Nakabayashi K; Yang W; Sato-Otsubo A; Tsujimoto SI; Ogata-Kawata H; Kawai T; Ishiwata K; Sakamoto M; Okamura K; Yoshida K; Shirai R; Osumi T; Kiyotani C; Shioda Y; Terashima K; Ishimaru S; Yuza Y; Takagi M; Arakawa Y; Imamura T; Hasegawa D; Inoue A; Yoshioka T; Ito S; Tomizawa D; Koh K; Matsumoto K; Kiyokawa N; Ogawa S; Manabe A; Niwa A; Hata K; Yang JJ; Kato M
Cancer Med; 2023 May; 12(10):11264-11273. PubMed ID: 37021926
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3. Autoantibodies to PAX5, ptch1, and GNA11 as Serological Biomarkers in the Detection of Hepatocellular Carcinoma in Hispanic Americans.
Qiu C; Ma Y; Wang B; Zhang X; Wang X; Zhang JY
Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835134
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4. Prediction of optimal cytogenetic responses at 6 and 12 months in patients with chronic myeloid leukemia in chronic phase treated with imatinib.
Milosevic V; Jovanovic MP; Bukumirić Z; Djordjevic V; Jovanovic J; Fekete MD; Lekovic D; Bogdanovic A
J BUON; 2021; 26(3):1070-1079. PubMed ID: 34268974
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5. [Expression and Significance of Shh Signaling Pathway in Bone Marrow CD34
Qin YT; Yao L; Yin Z; Chen S; Wang H; Fan WX; Jiang M; Hao JP
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2020 Oct; 28(5):1637-1642. PubMed ID: 33067966
[TBL] [Abstract] [Full Text] [Related]
6. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
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7. [Rapamycin Induces Apoptosis of K562 Cells through EZH2/Hedgehog Signaling Pathway].
He YX; Zhang HT; He PC
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2019 Oct; 27(5):1402-1408. PubMed ID: 31607290
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8. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
Katoh M
Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
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9. Targeting Hedgehog (Hh) Pathway for the Acute Myeloid leukemia Treatment.
Terao T; Minami Y
Cells; 2019 Apr; 8(4):. PubMed ID: 30987263
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10. Safety and Tolerability of Sonic Hedgehog Pathway Inhibitors in Cancer.
Carpenter RL; Ray H
Drug Saf; 2019 Feb; 42(2):263-279. PubMed ID: 30649745
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11. A novel hedgehog inhibitor for the treatment of hematological malignancies.
Lin P; He Y; Chen G; Ma H; Zheng J; Zhang Z; Cao B; Zhang H; Zhang X; Mao X
Anticancer Drugs; 2018 Nov; 29(10):995-1003. PubMed ID: 30106753
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12. Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.
Burns MA; Liao ZW; Yamagata N; Pouliot GP; Stevenson KE; Neuberg DS; Thorner AR; Ducar M; Silverman EA; Hunger SP; Loh ML; Winter SS; Dunsmore KP; Wood B; Devidas M; Harris MH; Silverman LB; Sallan SE; Gutierrez A
Leukemia; 2018 Oct; 32(10):2126-2137. PubMed ID: 29654263
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13. ptch1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase.
Alonso-Dominguez JM; Casado LF; Anguita E; Gomez-Casares MT; Buño I; Ferrer-Marín F; Arenas A; Del Orbe R; Ayala R; Llamas P; Salgado RN; Osorio S; Sanchez-Godoy P; Burgaleta C; Mahíllo-Fernández I; Garcia-Gutierrez V; Steegmann JL; Martinez-Lopez J
PLoS One; 2017; 12(7):e0181366. PubMed ID: 28704552
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14. GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.
Chaudhry P; Singh M; Triche TJ; Guzman M; Merchant AA
Blood; 2017 Jun; 129(26):3465-3475. PubMed ID: 28487292
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15. Assessment of Promoter Methylation Identifies ptch as a Putative Tumor-suppressor Gene in Human CLL.
Schmidt-Wolf IG; Plass C; Byrd JC; Frevel K; Pietsch T; Waha A
Anticancer Res; 2016 Sep; 36(9):4515-9. PubMed ID: 27630290
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16. SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature.
Mangum R; Varga E; Boué DR; Capper D; Benesch M; Leonard J; Osorio DS; Pierson CR; Zumberge N; Sahm F; Schrimpf D; Pfister SM; Finlay JL
Childs Nerv Syst; 2016 Dec; 32(12):2439-2446. PubMed ID: 27444290
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17. Pyrazolopyrimidine Derivatives as Antineoplastic Agents: with a Special Focus on Thyroid Cancer.
Ferrari SM; La Motta C; Sartini S; Baldini E; Materazzi G; Politti U; Ruffilli I; Ulisse S; Miccoli P; Antonelli A; Fallahi P
Mini Rev Med Chem; 2016; 16(2):86-93. PubMed ID: 26471970
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18. [Effect of As₂O₃on Hedgehog Pathway in Chronic Myeloid leukemia Cells].
He XW; Yan W; Yang W
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2015 Aug; 23(4):971-5. PubMed ID: 26314428
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19. The Hedgehog pathway: role in cell differentiation, polarity and proliferation.
Jia Y; Wang Y; Xie J
Arch Toxicol; 2015 Feb; 89(2):179-91. PubMed ID: 25559776
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20. ptch1 expression at diagnosis predicts imatinib failure in chronic myeloid leukaemia patients in chronic phase.
Alonso-Dominguez JM; Grinfeld J; Alikian M; Marin D; Reid A; Daghistani M; Hedgley C; O'Brien S; Clark RE; Apperley J; Foroni L; Gerrard G
Am J Hematol; 2015 Jan; 90(1):20-6. PubMed ID: 25250944
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