Terms: = Leukemia AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25
136 results:
1. Regulatory roles of CARD9-BCL10-rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?
Kowluru A
Biochem Pharmacol; 2023 Dec; 218():115889. PubMed ID: 37991197
[TBL] [Abstract] [Full Text] [Related]
2. A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
Ginn L; Maltas J; Baker MJ; Chaturvedi A; Wilson L; Guilbert R; Amaral FMR; Priest L; Mole H; Blackhall F; Diamantopoulou Z; Somervaille TCP; Hurlstone A; Malliri A
Proc Natl Acad Sci U S A; 2023 Oct; 120(40):e2300489120. PubMed ID: 37748077
[TBL] [Abstract] [Full Text] [Related]
3. RUNX1/ETO regulates reactive oxygen species (ROS) levels in t(8,21) acute myeloid leukaemia via FLT3 and rac1.
Azlan A; Khor KZ; Rajasegaran Y; Rosli AA; Said MSM; Yusoff NM; Moses EJ
Med Oncol; 2023 Jun; 40(7):208. PubMed ID: 37341821
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4. Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review.
Gomes AR; Varela CL; Pires AS; Tavares-da-Silva EJ; Roleira FMF
Bioorg Chem; 2023 Sep; 138():106600. PubMed ID: 37209561
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5. Single-cell resolution reveals RalA GTPase expanding hematopoietic stem cells and facilitating of BCR-ABL1-driven leukemogenesis in a CRISPR/Cas9 gene editing mouse model.
Yin Z; Su R; Ge L; Wang X; Yang J; Huang G; Li C; Liu Y; Zhang K; Deng L; Fei J
Int J Biol Sci; 2023; 19(4):1211-1227. PubMed ID: 36923939
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6. Diallyl disulfide downregulating RhoGDI2 induces differentiation and inhibit invasion via the rac1/Pak1/LIMK1 pathway in human leukemia HL-60 cells.
Hui T; Yiling J; Guangqun C; Ran L; Hui L; Lan Y; Jie H; Su Q
Environ Toxicol; 2023 May; 38(5):1063-1077. PubMed ID: 36793247
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7. Hypoxia regulates CD9 expression and dissemination of B lymphoblasts.
Rouger-Gaudichon J; Cousin E; Jakobczyk H; Debaize L; Rio AG; Forestier A; Arnaud MP; Villacreces A; Praloran V; Jacamo R; Galibert MD; Troadec MB; Gandemer V
Leuk Res; 2022 Dec; 123():106964. PubMed ID: 36335655
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8. CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
Grey W; Rio-Machin A; Casado P; Grönroos E; Ali S; Miettinen JJ; Bewicke-Copley F; Parsons A; Heckman CA; Swanton C; Cutillas PR; Gribben J; Fitzgibbon J; Bonnet D
Sci Transl Med; 2022 Jun; 14(650):eabn3248. PubMed ID: 35731890
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9. Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia.
Park K; Yoo HS; Oh CK; Lee JR; Chung HJ; Kim HN; Kim SH; Kee KM; Kim TY; Kim M; Kim BG; Ra JS; Myung K; Kim H; Han SH; Seo MD; Lee Y; Kim DW
Cancer Med; 2022 Nov; 11(21):4005-4020. PubMed ID: 35352878
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10. Rac GTPases in acute myeloid leukemia cells: Expression profile and biological effects of pharmacological inhibition.
Ramos DFV; Mancuso RI; Contieri B; Duarte A; Paiva L; de Melo Carrilho J; Saad STO; Lazarini M
Toxicol Appl Pharmacol; 2022 May; 442():115990. PubMed ID: 35331739
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11. 6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Chen D; Liu Y; Zhang F; You Q; Ma W; Wu J; Wu Z
Microbiol Spectr; 2021 Dec; 9(3):e0064621. PubMed ID: 34730435
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12. Biomarkers for gastrointestinal adverse events related to thiopurine therapy.
Zudeh G; Franca R; Stocco G; Decorti G
World J Gastroenterol; 2021 Oct; 27(38):6348-6356. PubMed ID: 34720526
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13. Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia.
Garitano-Trojaola A; Sancho A; Götz R; Eiring P; Walz S; Jetani H; Gil-Pulido J; Da Via MC; Teufel E; Rhodes N; Haertle L; Arellano-Viera E; Tibes R; Rosenwald A; Rasche L; Hudecek M; Sauer M; Groll J; Einsele H; Kraus S; Kortüm MK
Commun Biol; 2021 Jun; 4(1):799. PubMed ID: 34172833
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14. TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with rac1.
Pang Y; Zhao Y; Wang Y; Wang X; Wang R; Liu N; Li P; Ji M; Ye J; Sun T; Li J; Ma D; Lu F; Ji C
J Exp Clin Cancer Res; 2020 Aug; 39(1):158. PubMed ID: 32795319
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15. Oncogenic Kras
Hamarsheh S; Osswald L; Saller BS; Unger S; De Feo D; Vinnakota JM; Konantz M; Uhl FM; Becker H; Lübbert M; Shoumariyeh K; Schürch C; Andrieux G; Venhoff N; Schmitt-Graeff A; Duquesne S; Pfeifer D; Cooper MA; Lengerke C; Boerries M; Duyster J; Niemeyer CM; Erlacher M; Blazar BR; Becher B; Groß O; Brummer T; Zeiser R
Nat Commun; 2020 Apr; 11(1):1659. PubMed ID: 32246016
[TBL] [Abstract] [Full Text] [Related]
16. Diallyl disulfide induces downregulation and inactivation of cofilin 1 differentiation via the rac1/ROCK1/LIMK1 pathway in leukemia cells.
Ling H; Ji X; Lei Y; Jia Y; Liu F; Xia H; Tan H; Zeng X; Yi L; He J; Su Q
Int J Oncol; 2020 Mar; 56(3):772-782. PubMed ID: 32124958
[TBL] [Abstract] [Full Text] [Related]
17. Integrative Network Analysis of Differentially Methylated and Expressed Genes for Biomarker Identification in leukemia.
Sanchez R; Mackenzie SA
Sci Rep; 2020 Feb; 10(1):2123. PubMed ID: 32034170
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18. Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of rac1 activation.
Naci D; Berrazouane S; Barabé F; Aoudjit F
Sci Rep; 2019 Dec; 9(1):19455. PubMed ID: 31857649
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19. FLT3-ITD cooperates with rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways.
Wu M; Li L; Hamaker M; Small D; Duffield AS
Haematologica; 2019 Dec; 104(12):2418-2428. PubMed ID: 30975911
[TBL] [Abstract] [Full Text] [Related]
20. Combined inhibition of rac1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis.
Hlavac M; Dwucet A; Kast RE; Engelke J; Westhoff MA; Siegelin MD; Debatin KM; Wirtz CR; Halatsch ME; Karpel-Massler G
Cell Oncol (Dordr); 2019 Jun; 42(3):287-301. PubMed ID: 30859392
[TBL] [Abstract] [Full Text] [Related]
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