BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND SMAD2, MADH2, 4087, ENSG00000175387, MGC34440, MGC22139, hMAD-2, MADR2, JV18-1, hSMAD2, JV18
83 results:

  • 1. Treatment patterns, clinical outcomes and gene mutation characteristics of hepatitis B virus-associated mantle cell lymphoma.
    Feng J; Fei Y; Gao M; Meng X; Zeng D; Zou D; Ye H; Liang Y; Sun X; Liang R; Zhou H; Wang X; Zhang H
    Hematol Oncol; 2024 May; 42(3):e3268. PubMed ID: 38676394
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPK.
    Dai Q; Shi R; Zhang G; Wang Y; Ye L; Peng L; Guo S; He J; Yang H; Jiang Y
    Exp Biol Med (Maywood); 2024; 249():10111. PubMed ID: 38510491
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer.
    Zhang F; Yan Y; Cao X; Guo C; Wang K; Lv S
    Cell Death Dis; 2024 Mar; 15(3):218. PubMed ID: 38490994
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia.
    Zhang R; Miao J; Zhai M; Liu R; Li F; Xu X; Huang L; Wang T; Yang R; Yang R; Wang Y; He A; Wang J
    Mol Carcinog; 2024 Jun; 63(6):1146-1159. PubMed ID: 38477642
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. FAT1 inhibits AML autophagy and proliferation via downregulating ATG4B expression.
    Zhang N; Shen MY; Meng QL; Sun HP; Fan FY; Yi H; Yang YJ
    Biochim Biophys Acta Gen Subj; 2024 Jan; 1868(1):130519. PubMed ID: 37952564
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells.
    Hoeger B; Nadolni W; Hampe S; Hoelting K; Fraticelli M; Zaborsky N; Madlmayr A; Sperrer V; Fraticelli L; Addington L; Steinritz D; Chubanov V; Geisberger R; Greil R; Breit A; Boekhoff I; Gudermann T; Zierler S
    Function (Oxf); 2023; 4(6):zqad053. PubMed ID: 37786778
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Ginsenosides in cancer: Targeting cell cycle arrest and apoptosis.
    Shah MA; Abuzar SM; Ilyas K; Qadees I; Bilal M; Yousaf R; Kassim RMT; Rasul A; Saleem U; Alves MS; Khan H; Blundell R; Jeandet P
    Chem Biol Interact; 2023 Sep; 382():110634. PubMed ID: 37451663
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.
    Mascarenhas J; Migliaccio AR; Kosiorek H; Bhave R; Palmer J; Kuykendall A; Mesa R; Rampal RK; Gerds AT; Yacoub A; Pettit K; Talpaz M; Komrokji R; Kremyanskaya M; Gonzalez A; Fabris F; Johnson K; Dougherty M; McGovern E; Arango Ossa J; Domenico D; Farnoud N; Weinberg RS; Kong A; Najfeld V; Vannucchi AM; Arciprete F; Zingariello M; Falchi M; Salama ME; Mead-Harvey C; Dueck A; Varricchio L; Hoffman R
    Clin Cancer Res; 2023 Sep; 29(18):3622-3632. PubMed ID: 37439808
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The β-catenin-LINC00183-miR-371b-5p-smad2/LEF1 axis promotes adult T-cell lymphoblastic lymphoma progression and chemoresistance.
    Huang WJ; Guo SB; Shi H; Li XL; Zhu Y; Li M; Song LY; Yu RM; Cai QQ; Tian XP
    J Exp Clin Cancer Res; 2023 Apr; 42(1):105. PubMed ID: 37106379
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes.
    Manshouri T; Veletic I; Li P; Yin CC; Post SM; Verstovsek S; Estrov Z
    Cell Death Dis; 2022 May; 13(5):481. PubMed ID: 35595725
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Uvangoletin, extracted from Sarcandra glabra, exerts anticancer activity by inducing autophagy and apoptosis and inhibiting invasion and migration on hepatocellular carcinoma cells.
    Shen J; Zhu X; Wu Z; Shi Y; Wen T
    Phytomedicine; 2022 Jan; 94():153793. PubMed ID: 34736000
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
    Alejo-Valle O; Weigert K; Bhayadia R; Ng M; Issa H; Beyer C; Emmrich S; Schuschel K; Ihling C; Sinz A; Zimmermann M; Wickenhauser C; Flasinski M; Regenyi E; Labuhn M; Reinhardt D; Yaspo ML; Heckl D; Klusmann JH
    Blood; 2022 Feb; 139(5):651-665. PubMed ID: 34570885
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. TGF-β1 protein trap AVID200 beneficially affects hematopoiesis and bone marrow fibrosis in myelofibrosis.
    Varricchio L; Iancu-Rubin C; Upadhyaya B; Zingariello M; Martelli F; Verachi P; Clementelli C; Denis JF; Rahman AH; Tremblay G; Mascarenhas J; Mesa RA; O'Connor-McCourt M; Migliaccio AR; Hoffman R
    JCI Insight; 2021 Sep; 6(18):. PubMed ID: 34383713
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells.
    Wobus M; Mies A; Asokan N; Oelschlägel U; Möbus K; Winter S; Cross M; Weidner H; Rauner M; Hofbauer LC; Bornhäuser M; Platzbecker U
    Leukemia; 2021 Oct; 35(10):2936-2947. PubMed ID: 34002031
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) versus adult T-cell leukemia/lymphoma (ATLL).
    Zarei-Ghobadi M; Sheikhi M; Teymoori-Rad M; Yaslianifard S; Norouzi M; Yaslianifard S; Faraji R; Farahmand M; Bayat S; Jafari M; Mozhgani SH
    BMC Res Notes; 2021 Mar; 14(1):109. PubMed ID: 33757561
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.
    Erkeland SJ; Stavast CJ; Schilperoord-Vermeulen J; Dal Collo G; Van de Werken HJG; Leon LG; Van Hoven-Beijen A; Van Zuijen I; Mueller YM; Bindels EM; De Ridder D; Kappers-Klunne MC; Van Lom K; Van der Velden VHJ; Langerak AW
    Haematologica; 2022 Jan; 107(1):143-153. PubMed ID: 33596640
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis.
    Traxel S; Lehmann J; Richard S; Sidorov S; Niggli F; Berger C; Nadal D; Bürgler S
    Cancer Immunol Immunother; 2021 Aug; 70(8):2275-2289. PubMed ID: 33507341
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Oncogenic Long Noncoding RNA DARS-AS1 in Childhood Acute Myeloid leukemia by Binding to microRNA-425.
    Dou B; Jiang Z; Chen X; Wang C; Wu J; An J; Sheng G
    Technol Cancer Res Treat; 2020; 19():1533033820965580. PubMed ID: 33073700
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy.
    Pavlasova G; Mraz M
    Haematologica; 2020 Jun; 105(6):1494-1506. PubMed ID: 32482755
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. De novo damaging variants associated with congenital heart diseases contribute to the connectome.
    Ji W; Ferdman D; Copel J; Scheinost D; Shabanova V; Brueckner M; Khokha MK; Ment LR
    Sci Rep; 2020 Apr; 10(1):7046. PubMed ID: 32341405
    [TBL] [Abstract] [Full Text] [Related]  


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