BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396
76 results:

  • 1. Mast-cell expressed membrane protein-1 is expressed in classical monocytes and alveolar macrophages in idiopathic pulmonary fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ-dependent manner.
    Perrot CY; Karampitsakos T; Unterman A; Adams T; Marlin K; Arsenault A; Zhao A; Kaminski N; Katlaps G; Patel K; Bandyopadhyay D; Herazo-Maya JD
    Am J Physiol Cell Physiol; 2024 Mar; 326(3):C964-C977. PubMed ID: 38189137
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Biological activity of human IgE monoclonal antibodies targeting Der p 2, Fel d 1, Ara h 2 in basophil mediator release assays.
    Pena-Castellanos G; Smith BRE; Pomés A; Smith SA; Stigler MA; Widauer HL; Versteeg SA; van Ree R; Chapman MD; Aglas L
    Front Immunol; 2023; 14():1155613. PubMed ID: 37228609
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RNA
    Tan B; Zhou K; Liu W; Prince E; Qing Y; Li Y; Han L; Qin X; Su R; Pokharel SP; Yang L; Zhao Z; Shen C; Li W; Chen Z; Zhang Z; Deng X; Small A; Wang K; Leung K; Chen CW; Shen B; Chen J
    Theranostics; 2022; 12(13):5727-5743. PubMed ID: 35966596
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. ARID1A has prognostic value in acute myeloid leukemia and promotes cell proliferation via TGF-β1/smad3 signaling.
    Ren T; Wang J; Tang W; Chen D; Wang S; Zhang X; Yang D
    Clin Exp Med; 2023 Jul; 23(3):777-785. PubMed ID: 35867200
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. HLF regulates ferroptosis, development and chemoresistance of triple-negative breast cancer by activating tumor cell-macrophage crosstalk.
    Li H; Yang P; Wang J; Zhang J; Ma Q; Jiang Y; Wu Y; Han T; Xiang D
    J Hematol Oncol; 2022 Jan; 15(1):2. PubMed ID: 34991659
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The impact of gene-body H3K36me3 patterns on gene expression level changes in chronic myelogenous leukemia.
    Zhang LQ; Liu JJ; Liu L; Fan GL; Li YN; Li QZ
    Gene; 2021 Nov; 802():145862. PubMed ID: 34352296
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibition of TGF-β1 on Gli2 expression was promoted by TNF-α in primary leukemia cells.
    Li Z; Mao S; Zhang N
    J Recept Signal Transduct Res; 2022 Apr; 42(2):169-172. PubMed ID: 33615977
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.
    Erkeland SJ; Stavast CJ; Schilperoord-Vermeulen J; Dal Collo G; Van de Werken HJG; Leon LG; Van Hoven-Beijen A; Van Zuijen I; Mueller YM; Bindels EM; De Ridder D; Kappers-Klunne MC; Van Lom K; Van der Velden VHJ; Langerak AW
    Haematologica; 2022 Jan; 107(1):143-153. PubMed ID: 33596640
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.
    Selnø ATH; Schlichtner S; Yasinska IM; Sakhnevych SS; Fiedler W; Wellbrock J; Klenova E; Pavlova L; Gibbs BF; Degen M; Schnyder I; Aliu N; Berger SM; Fasler-Kan E; Sumbayev VV
    Aging (Albany NY); 2020 Dec; 12(23):23478-23496. PubMed ID: 33295886
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. TGFβR-smad3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.
    Le BV; Podszywalow-Bartnicka P; Maifrede S; Sullivan-Reed K; Nieborowska-Skorska M; Golovine K; Yao JC; Nejati R; Cai KQ; Caruso LB; Swatler J; Dabrowski M; Lian Z; Valent P; Paietta EM; Levine RL; Fernandez HF; Tallman MS; Litzow MR; Huang J; Challen GA; Link D; Tempera I; Wasik MA; Piwocka K; Skorski T
    Cell Rep; 2020 Oct; 33(1):108221. PubMed ID: 33027668
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. LncRNA-OBFC2A targeted to smad3 regulated Cyclin D1 influences cell cycle arrest induced by 1,4-benzoquinone.
    Guo X; Zhang W; Ren J; Chen Y; Wang J; Zhu C; Zhang Y; Gao A
    Toxicol Lett; 2020 Oct; 332():74-81. PubMed ID: 32645459
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Embryonic Program Activated during Blast Crisis of Chronic Myelogenous leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding.
    Desterke C; Hugues P; Hwang JW; Bennaceur-Griscelli A; Turhan AG
    Int J Mol Sci; 2020 Jun; 21(11):. PubMed ID: 32517078
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Miltefosine suppression of Pten null T-ALL leukemia via β-catenin degradation through inhibition of pT308-Akt and TGFβ1/smad3.
    Zhang Y; Lee S; Xu W
    Biochem Biophys Res Commun; 2020 Apr; 524(4):1018-1024. PubMed ID: 32063363
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.
    Fenaux P; Platzbecker U; Mufti GJ; Garcia-Manero G; Buckstein R; Santini V; Díez-Campelo M; Finelli C; Cazzola M; Ilhan O; Sekeres MA; Falantes JF; Arrizabalaga B; Salvi F; Giai V; Vyas P; Bowen D; Selleslag D; DeZern AE; Jurcic JG; Germing U; Götze KS; Quesnel B; Beyne-Rauzy O; Cluzeau T; Voso MT; Mazure D; Vellenga E; Greenberg PL; Hellström-Lindberg E; Zeidan AM; Adès L; Verma A; Savona MR; Laadem A; Benzohra A; Zhang J; Rampersad A; Dunshee DR; Linde PG; Sherman ML; Komrokji RS; List AF
    N Engl J Med; 2020 Jan; 382(2):140-151. PubMed ID: 31914241
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Epigenetic
    Ikemori R; Gabasa M; Duch P; Vizoso M; Bragado P; Arshakyan M; Luis IC; Marín A; Morán S; Castro M; Fuster G; Gea-Sorli S; Jauset T; Soucek L; Montuenga LM; Esteller M; Monsó E; Peinado VI; Gascon P; Fillat C; Hilberg F; Reguart N; Alcaraz J
    Cancer Res; 2020 Jan; 80(2):276-290. PubMed ID: 31694906
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the smad2/smad3 Pathway.
    Nie MF; Xie Q; Wu YH; He H; Zou LJ; She XL; Wu XQ
    J Immunol Res; 2018; 2018():6285813. PubMed ID: 30276219
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. High expression levels of smad3 and smad7 at diagnosis predict poor prognosis in acute myeloid leukemia patients undergoing chemotherapy.
    Zhang J; Zhang L; Cui H; Zhang X; Zhang G; Yang X; Yang S; Zhang Z; Wang J; Hu K; Shi J; Ke X; Fu L
    Cancer Gene Ther; 2019 May; 26(5-6):119-127. PubMed ID: 30177817
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Blockade of TGF-β/smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis.
    Luong VH; Chino T; Oyama N; Matsushita T; Sasaki Y; Ogura D; Niwa SI; Biswas T; Hamasaki A; Fujita M; Okamoto Y; Otsuka M; Ihn H; Hasegawa M
    Arthritis Res Ther; 2018 Mar; 20(1):46. PubMed ID: 29544542
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Lactic Acid Downregulates Viral MicroRNA To Promote Epstein-Barr Virus-Immortalized B Lymphoblastic Cell Adhesion and Growth.
    Mo X; Wei F; Tong Y; Ding L; Zhu Q; Du S; Tan F; Zhu C; Wang Y; Yu Q; Liu Y; Robertson ES; Yuan Z; Cai Q
    J Virol; 2018 May; 92(9):. PubMed ID: 29444941
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Effect and mechanism of RNAi targeting WWTR1 on biological activity of gastric cancer cells SGC7901.
    Li Y; Yang FL; Zhu CF; Tang LM
    Mol Med Rep; 2018 Feb; 17(2):2853-2860. PubMed ID: 29207147
    [TBL] [Abstract] [Full Text] [Related]  


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