BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4
54 results:

  • 1. New genetic drivers in hemorrhagic hereditary telangiectasia.
    Cerdà P; Castillo SD; Aguilera C; Iriarte A; Rocamora JL; Larrinaga AM; Viñals F; Graupera M; Riera-Mestre A
    Eur J Intern Med; 2024 Jan; 119():99-108. PubMed ID: 37689549
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Imatinib blocks tyrosine phosphorylation of smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia.
    Wang L; Gu S; Chen F; Yu Y; Cao J; Li X; Gao C; Chen Y; Yuan S; Liu X; Qin J; Zhao B; Xu P; Liang T; Tong H; Lin X; Feng XH
    Signal Transduct Target Ther; 2023 Mar; 8(1):120. PubMed ID: 36959211
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. E3 ubiquitin ligase ASB8 promotes selinexor-induced proteasomal degradation of XPO1.
    Kwanten B; Deconick T; Walker C; Wang F; Landesman Y; Daelemans D
    Biomed Pharmacother; 2023 Apr; 160():114305. PubMed ID: 36731340
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.
    Zhang H; Zhan Q; Wang X; Gao F; Yu J; Wang J; Fu W; Wang P; Wei X; Zhang L
    Ann Hematol; 2022 Dec; 101(12):2583-2600. PubMed ID: 36181538
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Genetic alterations during the neoplastic cascade towards cholangiocarcinoma in primary sclerosing cholangitis.
    Kamp EJ; Dinjens WN; Doukas M; van Marion R; Verheij J; Ponsioen CY; Bruno MJ; Groot Koerkamp B; Trivedi PJ; Peppelenbosch MP; de Vries AC
    J Pathol; 2022 Nov; 258(3):227-235. PubMed ID: 35897137
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas.
    Gkountakos A; Mafficini A; Lou E; Malleo G; Salvia R; Calicchia M; Silvestris N; Racila E; Amin K; Veronese N; Brunetti O; Antonini P; Ingravallo G; Mattiolo P; Saponaro C; Nappo F; Simbolo M; Bariani E; Lonardi S; Fassan M; Milella M; Lawlor RT; Scarpa A; Luchini C
    Hum Pathol; 2022 Oct; 128():124-133. PubMed ID: 35850360
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Differences in actionable genomic alterations between brain metastases and non‑brain metastases in patients with non‑small cell lung cancer.
    Nian R; Jiang H; Zhao J; Hou W; Zhang H; Ma J; Lv P; Jiang L; Wang Y; Xu Y; Wu S; Lou J; Li W
    Int J Oncol; 2022 Sep; 61(3):. PubMed ID: 35796015
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche.
    Yao JC; Oetjen KA; Wang T; Xu H; Abou-Ezzi G; Krambs JR; Uttarwar S; Duncavage EJ; Link DC
    J Clin Invest; 2022 Jun; 132(11):. PubMed ID: 35439167
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Downregulation of smad4 expression confers chemoresistance against imatinib mesylate to chronic myeloid leukemia K562 cells.
    Zhang J; Zhang M; Liang Y; Liu M; Huang Z
    Hematology; 2022 Dec; 27(1):43-52. PubMed ID: 34957936
    [No Abstract]    [Full Text] [Related]  

  • 10. The impact of gene-body H3K36me3 patterns on gene expression level changes in chronic myelogenous leukemia.
    Zhang LQ; Liu JJ; Liu L; Fan GL; Li YN; Li QZ
    Gene; 2021 Nov; 802():145862. PubMed ID: 34352296
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.
    Yan HHN; Siu HC; Ho SL; Yue SSK; Gao Y; Tsui WY; Chan D; Chan AS; Wong JWH; Man AHY; Lee BCH; Chan ASY; Chan AKW; Hui HS; Cheung AKL; Law WL; Lo OSH; Yuen ST; Clevers H; Leung SY
    Gut; 2020 Dec; 69(12):2165-2179. PubMed ID: 32217638
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
    Schwörer S; Berisa M; Violante S; Qin W; Zhu J; Hendrickson RC; Cross JR; Thompson CB
    EMBO J; 2020 Apr; 39(8):e103334. PubMed ID: 32134147
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Upregulated microRNA-146a expression induced by granulocyte colony-stimulating factor enhanced low-dosage chemotherapy response in aged acute myeloid leukemia patients.
    Li X; Xu L; Sheng X; Cai J; Liu J; Yin T; Xiao F; Chen F; Zhong H
    Exp Hematol; 2018 Dec; 68():66-79.e3. PubMed ID: 30208330
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
    Khan M; Loree JM; Advani SM; Ning J; Li W; Pereira AAL; Lam M; Raghav K; Morris VK; Broaddus R; Maru D; Overman MJ; Kopetz S
    Clin Colorectal Cancer; 2018 Dec; 17(4):e699-e709. PubMed ID: 30205948
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia.
    Witkowska M; Majchrzak A; Cebula-Obrzut B; Wawrzyniak E; Robak T; Smolewski P
    Tumour Biol; 2017 Mar; 39(3):1010428317694551. PubMed ID: 28349818
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia.
    Saleh LM; Wang W; Herman SE; Saba NS; Anastas V; Barber E; Corrigan-Cummins M; Farooqui M; Sun C; Sarasua SM; Zhao Z; Abousamra NK; Elbaz O; Abdelghaffar HA; Wiestner A; Calvo KR
    Leukemia; 2017 Feb; 31(2):340-349. PubMed ID: 27431016
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Binding of a smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia.
    Raz S; Stark M; Assaraf YG
    Oncotarget; 2014 Oct; 5(19):9183-98. PubMed ID: 25229333
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. miR-146a expression level as a novel putative prognostic marker for acute promyelocytic leukemia.
    Xu L; Zhong H; Wan H; Chen FY; Zhong J; Xiao F; Liu J; Shen L
    Dis Markers; 2014; 2014():150604. PubMed ID: 25161335
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The diaryl oxazole PC-046 is a tubulin-binding agent with experimental anti-tumor efficacy in hematologic cancers.
    Landowski TH; Samulitis BK; Dorr RT
    Invest New Drugs; 2013 Dec; 31(6):1616-25. PubMed ID: 24037082
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells.
    Li Z; Fei T; Zhang J; Zhu G; Wang L; Lu D; Chi X; Teng Y; Hou N; Yang X; Zhang H; Han JD; Chen YG
    Cell Stem Cell; 2012 Feb; 10(2):171-82. PubMed ID: 22305567
    [TBL] [Abstract] [Full Text] [Related]  


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