BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND SMARCA4, hSNF2b, 6597, P51532, BRG1, SNF2L4, SNF2, SWI2, FLJ39786, BAF190, SNF2LB, SNF2-BETA, ENSG00000127616
79 results:

  • 1. smarca4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions.
    Deng Q; Lakra P; Gou P; Yang H; Meydan C; Teater M; Chin C; Zhang W; Dinh T; Hussein U; Li X; Rojas E; Liu W; Reville PK; Kizhakeyil A; Barisic D; Parsons S; Wilson A; Henderson J; Scull B; Gurumurthy C; Vega F; Chadburn A; Cuglievan B; El-Mallawany NK; Allen C; Mason C; Melnick A; Green MR
    Cancer Cell; 2024 Apr; 42(4):605-622.e11. PubMed ID: 38458188
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. brg1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor.
    Fiskus W; Piel J; Collins M; Hentemann M; Cuglievan B; Mill CP; Birdwell CE; Das K; Davis JA; Hou H; Jain A; Malovannaya A; Kadia TM; Daver N; Sasaki K; Takahashi K; Hammond D; Reville PK; Wang J; Loghavi S; Sen R; Ruan X; Su X; Flores LB; DiNardo CD; Bhalla KN
    Blood; 2024 May; 143(20):2059-2072. PubMed ID: 38437498
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. MC180295 is a highly potent and selective CDK9 inhibitor with preclinical in vitro and in vivo efficacy in cancer.
    Zhang H; Huang C; Gordon J; Yu S; Morton G; Childers W; Abou-Gharbia M; Zhang Y; Jelinek J; Issa JJ
    Clin Epigenetics; 2024 Jan; 16(1):3. PubMed ID: 38172923
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Synchronous T-lymphoblastic lymphoma and neuroblastoma in a 3-yr-old with novel germline
    Tibout P; Livingston J; Kanwar N; Yuki KE; Shlien A; Ngan B; Irwin MS; Morgenstern DA; Hitzler J; Villani A; Cohen-Gogo S
    Cold Spring Harb Mol Case Stud; 2023 Dec; 9(4):. PubMed ID: 37932047
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.
    Aoki K; Hyuga M; Tarumoto Y; Nishibuchi G; Ueda A; Ochi Y; Sugino S; Mikami T; Kobushi H; Kato I; Akahane K; Inukai T; Takaori-Kondo A; Takita J; Ogawa S; Yusa K
    Blood; 2024 Feb; 143(7):604-618. PubMed ID: 37922452
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Comparative Analysis of the Embryonal Brain Tumors Based on Their Molecular Features.
    Shcherbina V; Kovalevska L; Pedachenko E; Malysheva T; Kashuba E
    Discov Med; 2023 Oct; 35(178):733-749. PubMed ID: 37811612
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice.
    Li BE; Li GY; Cai W; Zhu Q; Seruggia D; Fujiwara Y; Vakoc CR; Orkin SH
    Blood Adv; 2023 Sep; 7(18):5281-5293. PubMed ID: 37428871
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ZNF384-Related Fusion Genes in Acute Lymphoblastic leukemia.
    Zhu L; Bai W; Cheng Q; Fang J
    Cancer Control; 2023; 30():10732748231182787. PubMed ID: 37306722
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. ERCC6L2-related disease: a novel entity of bone marrow failure disorder with high risk of clonal evolution.
    Baccelli F; Leardini D; Cerasi S; Messelodi D; Bertuccio SN; Masetti R
    Ann Hematol; 2023 Apr; 102(4):699-705. PubMed ID: 36790458
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation.
    Pandey RV; Strobl J; Redl A; Unterluggauer L; Gail L; Kleissl L; Müller S; Atzmüller D; Fife-Gernedl V; Krausgruber T; Knaus H; Mitterbauer M; Wohlfarth P; Rabitsch W; Bock C; Stary G
    Clin Immunol; 2023 Mar; 248():109245. PubMed ID: 36702179
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age.
    Burkhardt B; Michgehl U; Rohde J; Erdmann T; Berning P; Reutter K; Rohde M; Borkhardt A; Burmeister T; Dave S; Tzankov A; Dugas M; Sandmann S; Fend F; Finger J; Mueller S; Gökbuget N; Haferlach T; Kern W; Hartmann W; Klapper W; Oschlies I; Richter J; Kontny U; Lutz M; Maecker-Kolhoff B; Ott G; Rosenwald A; Siebert R; von Stackelberg A; Strahm B; Woessmann W; Zimmermann M; Zapukhlyak M; Grau M; Lenz G
    Nat Commun; 2022 Jul; 13(1):3881. PubMed ID: 35794096
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Exquisite Sensitivity to Dual brg1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid leukemia.
    Rago F; Rodrigues LU; Bonney M; Sprouffske K; Kurth E; Elliott G; Ambrose J; Aspesi P; Oborski J; Chen JT; McDonald ER; Mapa FA; Ruddy DA; Kauffmann A; Abrams T; Bhang HC; Jagani Z
    Mol Cancer Res; 2022 Mar; 20(3):361-372. PubMed ID: 34799403
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells.
    Jeong KW
    Curr Issues Mol Biol; 2021 Oct; 43(3):1623-1631. PubMed ID: 34698116
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. smarca4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
    Romero OA; Vilarrubi A; Alburquerque-Bejar JJ; Gomez A; Andrades A; Trastulli D; Pros E; Setien F; Verdura S; Farré L; Martín-Tejera JF; Llabata P; Oaknin A; Saigi M; Piulats JM; Matias-Guiu X; Medina PP; Vidal A; Villanueva A; Sanchez-Cespedes M
    Nat Commun; 2021 Jul; 12(1):4319. PubMed ID: 34262032
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. NUT carcinoma of the lung.
    Lantuejoul S; Pissaloux D; Ferretti GR; McLeer A
    Semin Diagn Pathol; 2021 Sep; 38(5):72-82. PubMed ID: 34176698
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The BAFfling story of MN1-induced leukemogenesis.
    Stonestrom AJ; Levine RL
    Mol Cell; 2021 Jun; 81(11):2268-2269. PubMed ID: 34087176
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia.
    Fabiani E; Cicconi L; Nardozza AM; Cristiano A; Rossi M; Ottone T; Falconi G; Divona M; Testi AM; Annibali O; Castelli R; Lazarevic V; Rego E; Montesinos P; Esteve J; Venditti A; Della Porta M; Arcese W; Lo-Coco F; Voso MT
    Cancer Med; 2021 Jun; 10(12):3839-3847. PubMed ID: 34042280
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. FUS oncofusion protein condensates recruit mSWI/SNF chromatin remodeler via heterotypic interactions between prion-like domains.
    Davis RB; Kaur T; Moosa MM; Banerjee PR
    Protein Sci; 2021 Jul; 30(7):1454-1466. PubMed ID: 34018649
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Aberrant Cytoplasmic Terminal Deoxynucleotidyl Transferase (TdT) Immunostaining on Previously Frozen, Formalin-fixed Paraffin-embedded Tissue: Cryotomy-induced Antigen Diffusion (CIAD).
    Henwood AF
    Appl Immunohistochem Mol Morphol; 2021 Feb; 29(2):e17-e19. PubMed ID: 32590454
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL.
    Jain P; Zhang S; Kanagal-Shamanna R; Ok CY; Nomie K; Gonzalez GN; Gonzalez-Pagan O; Hill HA; Lee HJ; Fayad L; Westin J; Nastoupil L; Hagemeister F; Chen W; Oriabure O; Badillo M; Jiang C; Yixin Y; Li S; Tang G; Yin CC; Patel KP; Medeiros LJ; Nair R; Ahmed S; Iyer SP; Thirumurthi S; Champlin R; Xu G; Tinsu P; Santos D; Wang R; Han G; Zhang J; Song X; Neelapu S; Romaguera J; Futreal A; Flowers C; Fowler N; Wang L; Wang ML
    Blood Adv; 2020 Mar; 4(6):1038-1050. PubMed ID: 32191807
    [TBL] [Abstract] [Full Text] [Related]  


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