Terms: = Leukemia AND SMARCA4, hSNF2b, 6597, P51532, BRG1, SNF2L4, SNF2, SWI2, FLJ39786, BAF190, SNF2LB, SNF2-BETA, ENSG00000127616 AND Treatment
17 results:
1. brg1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor.
Fiskus W; Piel J; Collins M; Hentemann M; Cuglievan B; Mill CP; Birdwell CE; Das K; Davis JA; Hou H; Jain A; Malovannaya A; Kadia TM; Daver N; Sasaki K; Takahashi K; Hammond D; Reville PK; Wang J; Loghavi S; Sen R; Ruan X; Su X; Flores LB; DiNardo CD; Bhalla KN
Blood; 2024 May; 143(20):2059-2072. PubMed ID: 38437498
[TBL] [Abstract] [Full Text] [Related]
2. Synchronous T-lymphoblastic lymphoma and neuroblastoma in a 3-yr-old with novel germline
Tibout P; Livingston J; Kanwar N; Yuki KE; Shlien A; Ngan B; Irwin MS; Morgenstern DA; Hitzler J; Villani A; Cohen-Gogo S
Cold Spring Harb Mol Case Stud; 2023 Dec; 9(4):. PubMed ID: 37932047
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3. Comparative Analysis of the Embryonal Brain Tumors Based on Their Molecular Features.
Shcherbina V; Kovalevska L; Pedachenko E; Malysheva T; Kashuba E
Discov Med; 2023 Oct; 35(178):733-749. PubMed ID: 37811612
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4. ERCC6L2-related disease: a novel entity of bone marrow failure disorder with high risk of clonal evolution.
Baccelli F; Leardini D; Cerasi S; Messelodi D; Bertuccio SN; Masetti R
Ann Hematol; 2023 Apr; 102(4):699-705. PubMed ID: 36790458
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5. An interaction between MKL1, brg1, and C/EBPβ mediates palmitate induced CRP transcription in hepatocytes.
Fan Z; Li N; Xu Z; Wu J; Fan X; Xu Y
Biochim Biophys Acta Gene Regul Mech; 2019 Sep; 1862(9):194412. PubMed ID: 31356989
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6. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Farnaby W; Koegl M; Roy MJ; Whitworth C; Diers E; Trainor N; Zollman D; Steurer S; Karolyi-Oezguer J; Riedmueller C; Gmaschitz T; Wachter J; Dank C; Galant M; Sharps B; Rumpel K; Traxler E; Gerstberger T; Schnitzer R; Petermann O; Greb P; Weinstabl H; Bader G; Zoephel A; Weiss-Puxbaum A; Ehrenhöfer-Wölfer K; Wöhrle S; Boehmelt G; Rinnenthal J; Arnhof H; Wiechens N; Wu MY; Owen-Hughes T; Ettmayer P; Pearson M; McConnell DB; Ciulli A
Nat Chem Biol; 2019 Jul; 15(7):672-680. PubMed ID: 31178587
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7. Degron mediated BRM/SMARCA2 depletion uncovers novel combination partners for treatment of brg1/smarca4-mutant cancers.
Rago F; DiMare MT; Elliott G; Ruddy DA; Sovath S; Kerr G; Bhang HC; Jagani Z
Biochem Biophys Res Commun; 2019 Jan; 508(1):109-116. PubMed ID: 30527810
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8. A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia.
Lee SI; Celik S; Logsdon BA; Lundberg SM; Martins TJ; Oehler VG; Estey EH; Miller CP; Chien S; Dai J; Saxena A; Blau CA; Becker PS
Nat Commun; 2018 Jan; 9(1):42. PubMed ID: 29298978
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9. [Oridonin inhibits proliferation of Jurkat cells via the down-regulation of brg1].
Ye ZZ; Xue FL; Ding WP; Kong X; Shen YN
Zhongguo Dang Dai Er Ke Za Zhi; 2017 Nov; 19(11):1208-1212. PubMed ID: 29132471
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10. brg1 regulation by miR-155 in human leukemia and lymphoma cell lines.
Cuadros M; Sánchez-Martín V; Herrera A; Baliñas C; Martín-Padrón J; Boyero L; Peinado P; Medina PP
Clin Transl Oncol; 2017 Aug; 19(8):1010-1017. PubMed ID: 28251496
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11. [Research Progress on the Role of Chromatin Remodeling Factor brg1 in Acute Myeloid leukemia].
Gao S; Xu XJ; Zhang K
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2016 Jun; 24(3):930-3. PubMed ID: 27342536
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12. Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.
Kunz JB; Rausch T; Bandapalli OR; Eilers J; Pechanska P; Schuessele S; Assenov Y; Stütz AM; Kirschner-Schwabe R; Hof J; Eckert C; von Stackelberg A; Schrappe M; Stanulla M; Koehler R; Avigad S; Elitzur S; Handgretinger R; Benes V; Weischenfeldt J; Korbel JO; Muckenthaler MU; Kulozik AE
Haematologica; 2015 Nov; 100(11):1442-50. PubMed ID: 26294725
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13. The novel arsenical Darinaparsin circumvents brg1-dependent, HO-1-mediated cytoprotection in leukemic cells.
Garnier N; Petruccelli LA; Molina MF; Kourelis M; Kwan S; Diaz Z; Schipper HM; Gupta A; del Rincon SV; Mann KK; Miller WH
Leukemia; 2013 Nov; 27(11):2220-8. PubMed ID: 23426167
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14. The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.
Pottier N; Yang W; Assem M; Panetta JC; Pei D; Paugh SW; Cheng C; Den Boer ML; Relling MV; Pieters R; Evans WE; Cheok MH
J Natl Cancer Inst; 2008 Dec; 100(24):1792-803. PubMed ID: 19066270
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15. MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.
Morey L; Brenner C; Fazi F; Villa R; Gutierrez A; Buschbeck M; Nervi C; Minucci S; Fuks F; Di Croce L
Mol Cell Biol; 2008 Oct; 28(19):5912-23. PubMed ID: 18644863
[TBL] [Abstract] [Full Text] [Related]
16. The Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential.
Yamamichi N; Yamamichi-Nishina M; Mizutani T; Watanabe H; Minoguchi S; Kobayashi N; Kimura S; Ito T; Yahagi N; Ichinose M; Omata M; Iba H
Oncogene; 2005 Aug; 24(35):5471-81. PubMed ID: 16007216
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17. Maintenance of integrated proviral gene expression requires Brm, a catalytic subunit of SWI/SNF complex.
Mizutani T; Ito T; Nishina M; Yamamichi N; Watanabe A; Iba H
J Biol Chem; 2002 May; 277(18):15859-64. PubMed ID: 11850427
[TBL] [Abstract] [Full Text] [Related]
