Terms: = Leukemia AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS
33 results:
1. STAT3/lkb1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Pencik J; Philippe C; Schlederer M; Atas E; Pecoraro M; Grund-Gröschke S; Li WJ; Tracz A; Heidegger I; Lagger S; Trachtová K; Oberhuber M; Heitzer E; Aksoy O; Neubauer HA; Wingelhofer B; Orlova A; Witzeneder N; Dillinger T; Redl E; Greiner G; D'Andrea D; Östman JR; Tangermann S; Hermanova I; Schäfer G; Sternberg F; Pohl EE; Sternberg C; Varady A; Horvath J; Stoiber D; Malcolm TI; Turner SD; Parkes EE; Hantusch B; Egger G; Rose-John S; Poli V; Jain S; Armstrong CWD; Hoermann G; Goffin V; Aberger F; Moriggl R; Carracedo A; McKinney C; Kennedy RD; Klocker H; Speicher MR; Tang DG; Moazzami AA; Heery DM; Hacker M; Kenner L
Mol Cancer; 2023 Aug; 22(1):133. PubMed ID: 37573301
[TBL] [Abstract] [Full Text] [Related]
2. lkb1 controls inflammatory potential through CRTC2-dependent histone acetylation.
Compton SE; Kitchen-Goosen SM; DeCamp LM; Lau KH; Mabvakure B; Vos M; Williams KS; Wong KK; Shi X; Rothbart SB; Krawczyk CM; Jones RG
Mol Cell; 2023 Jun; 83(11):1872-1886.e5. PubMed ID: 37172591
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3. Acetylshikonin induces autophagy-dependent apoptosis through the key lkb1-AMPK and PI3K/Akt-regulated mTOR signalling pathways in HL-60 cells.
Wu MD; Zhang YY; Yi SY; Sun BB; Lan J; Jiang HM; Hao GP
J Cell Mol Med; 2022 Mar; 26(5):1606-1620. PubMed ID: 35106915
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4. Can molecular insights guide treatment of AML evolved from MPNs?
Crispino J; Rampal R
Best Pract Res Clin Haematol; 2021 Dec; 34(4):101323. PubMed ID: 34865695
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5. Enhanced Vulnerability of lkb1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
Galan-Cobo A; Stellrecht CM; Yilmaz E; Yang C; Qian Y; Qu X; Akhter I; Ayres ML; Fan Y; Tong P; Diao L; Ding J; Giri U; Gudikote J; Nilsson M; Wierda WG; Wang J; Skoulidis F; Minna JD; Gandhi V; Heymach JV
Mol Cancer Res; 2022 Feb; 20(2):280-292. PubMed ID: 34654720
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6. [Expression Level of lkb1 Gene in Patients with Acute Lymphoblastic leukemia and Its Correlation with Illness Condition].
Han F; Lai TW; Li H; Tan WM; Wu J
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2020 Apr; 28(2):464-469. PubMed ID: 32319380
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7. Genetic manipulation of lkb1 elicits lethal metastatic prostate cancer.
Hermanova I; Zúñiga-García P; Caro-Maldonado A; Fernandez-Ruiz S; Salvador F; Martín-Martín N; Zabala-Letona A; Nuñez-Olle M; Torrano V; Camacho L; Lizcano JM; Talamillo A; Carreira S; Gurel B; Cortazar AR; Guiu M; López JI; Martinez-Romero A; Astobiza I; Valcarcel-Jimenez L; Lorente M; Arruabarrena-Aristorena A; Velasco G; Gomez-Muñoz A; Suárez-Cabrera C; Lodewijk I; Flores JM; Sutherland JD; Barrio R; de Bono JS; Paramio JM; Trka J; Graupera M; Gomis RR; Carracedo A
J Exp Med; 2020 Jun; 217(6):. PubMed ID: 32219437
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8. Clonal evolution of chronic lymphocytic leukemia to Langerhans cell histiocytosis: a case report.
Frauenfeld L; Bonzheim I; Wirths S; Steinhilber J; Horger M; Mankel B; Bethge W; Fend F; Federmann B
Virchows Arch; 2019 Dec; 475(6):795-798. PubMed ID: 31317311
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9. Mitochondrial dysfunction regulates the JAK-STAT pathway via lkb1-mediated AMPK activation ER-stress-independent manner.
Kim DY; Lim SG; Suk K; Lee WH
Biochem Cell Biol; 2020 Apr; 98(2):137-144. PubMed ID: 31071273
[TBL] [Abstract] [Full Text] [Related]
10. Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance.
Cristofoletti C; Bresin A; Picozza M; Picchio MC; Monzo F; Helmer Citterich M; Passarelli F; Frezzolini A; Scala E; Monopoli A; Cantonetti M; Benucci R; D'Atri S; Caprini E; Russo G; Narducci MG
Leukemia; 2019 May; 33(5):1231-1242. PubMed ID: 30518812
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11. Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation.
Jacquel A; Luciano F; Robert G; Auberger P
Int J Mol Sci; 2018 Sep; 19(10):. PubMed ID: 30274374
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12. Impact of earlier versus later monitoring on disease progression and healthcare costs among patients with chronic myeloid leukemia in the United States.
Jabbour EJ; Siegartel LR; Lin J; Lingohr-Smith M; Menges B; Makenbaeva D
Leuk Lymphoma; 2019 Mar; 60(3):668-674. PubMed ID: 30124372
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13. lkb1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid leukemia.
Tarumoto Y; Lu B; Somerville TDD; Huang YH; Milazzo JP; Wu XS; Klingbeil O; El Demerdash O; Shi J; Vakoc CR
Mol Cell; 2018 Mar; 69(6):1017-1027.e6. PubMed ID: 29526696
[TBL] [Abstract] [Full Text] [Related]
14. Cinacalcet-mediated activation of the CaMKKβ-lkb1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy.
Lim JH; Kim HW; Kim MY; Kim TW; Kim EN; Kim Y; Chung S; Kim YS; Choi BS; Kim YS; Chang YS; Kim HW; Park CW
Cell Death Dis; 2018 Feb; 9(3):270. PubMed ID: 29449563
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15. Phe354Leu Polymorphism of
Yang MY; Hsiao HH; Liu YC; Hsu CM; Lin SF; Lin PM
In Vivo; 2017; 31(5):841-847. PubMed ID: 28882949
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16. Live kinase B1 maintains CD34
Wang H; Wang X; Xin N; Qi L; Liao A; Yang W; Liu Z; Zhao C
Mol Cell Biochem; 2017 Oct; 434(1-2):25-32. PubMed ID: 28397012
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17. Characterization of bioactive constituents from the gum resin of Gardenia lucida and its pharmacological potential.
Maurya P; Singh S; Gupta MM; Luqman S
Biomed Pharmacother; 2017 Jan; 85():444-456. PubMed ID: 27899258
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18. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.
Zucal C; D'Agostino VG; Casini A; Mantelli B; Thongon N; Soncini D; Caffa I; Cea M; Ballestrero A; Quattrone A; Indraccolo S; Nencioni A; Provenzani A
BMC Cancer; 2015 Nov; 15():855. PubMed ID: 26542945
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19. The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML.
Obba S; Hizir Z; Boyer L; Selimoglu-Buet D; Pfeifer A; Michel G; Hamouda MA; Gonçalvès D; Cerezo M; Marchetti S; Rocchi S; Droin N; Cluzeau T; Robert G; Luciano F; Robaye B; Foretz M; Viollet B; Legros L; Solary E; Auberger P; Jacquel A
Autophagy; 2015; 11(7):1114-29. PubMed ID: 26029847
[TBL] [Abstract] [Full Text] [Related]
20. Negative regulation of the lkb1/AMPK pathway by ERK in human acute myeloid leukemia cells.
Kawashima I; Mitsumori T; Nozaki Y; Yamamoto T; Shobu-Sueki Y; Nakajima K; Kirito K
Exp Hematol; 2015 Jul; 43(7):524-33.e1. PubMed ID: 25846811
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