Terms: = Leukemia AND SUZ12, CHET9, 23512, ENSG00000178691, Q15022, KIAA0160, JJAZ1 AND Treatment
22 results:
1. Distinct mutational pattern of T-cell large granular lymphocyte leukemia combined with pure red cell aplasia: low mutational burden of STAT3.
Park S; Yun J; Choi SY; Jeong D; Gu JY; Lee JS; Seong MW; Chang YH; Yun H; Kim HK
Sci Rep; 2023 May; 13(1):7280. PubMed ID: 37142644
[TBL] [Abstract] [Full Text] [Related]
2. Prognostic utility of key copy number alterations in T cell acute lymphoblastic leukemia.
Kumari S; Ali MS; Singh J; Arora M; Verma D; Pandey AK; Benjamin M; Bakhshi S; Palanichamy JK; Sharma A; Singh I; Tanwar P; Singh AR; Pushpam D; Qamar I; Chopra A
Hematol Oncol; 2022 Oct; 40(4):577-587. PubMed ID: 35644022
[TBL] [Abstract] [Full Text] [Related]
3. Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML.
Yang F; Long N; Anekpuritanang T; Bottomly D; Savage JC; Lee T; Solis-Ruiz J; Borate U; Wilmot B; Tognon C; Bock AM; Pollyea DA; Radhakrishnan S; Radhakrishnan S; Patel P; Collins RH; Tantravahi S; Deininger MW; Fan G; Druker B; Shinde U; Tyner JW; Press RD; McWeeney S; Agarwal A
Blood; 2022 Feb; 139(8):1208-1221. PubMed ID: 34482403
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4. Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies.
Kaito S; Iwama A
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33374737
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5. A Noncanonical Function of Polycomb Repressive Complexes Promotes Human Cytomegalovirus Lytic DNA Replication and Serves as a Novel Cellular Target for Antiviral Intervention.
Svrlanska A; Reichel A; Schilling EM; Scherer M; Stamminger T; Reuter N
J Virol; 2019 May; 93(9):. PubMed ID: 30814291
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6. Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
Vitkeviciene A; Baksiene S; Borutinskaite V; Navakauskiene R
Eur J Pharmacol; 2018 Nov; 838():32-40. PubMed ID: 30194939
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7. Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds.
León-González AJ; Jara-Palacios MJ; Abbas M; Heredia FJ; Schini-Kerth VB
Food Funct; 2017 Nov; 8(11):4062-4069. PubMed ID: 28976514
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8. Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells.
Borutinskaitė V; Virkšaitė A; Gudelytė G; Navakauskienė R
Leuk Lymphoma; 2018 Feb; 59(2):469-478. PubMed ID: 28641467
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9. Effect and Mechanism of Curcumin on EZH2 - miR-101 Regulatory Feedback Loop in Multiple Myeloma.
Wu C; Ruan T; Liu W; Zhu X; Pan J; Lu W; Yan C; Tao K; Zhang W; Zhang C
Curr Pharm Des; 2018; 24(5):564-575. PubMed ID: 28322158
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10. Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells.
Valiulienė G; Stirblytė I; Jasnauskaitė M; Borutinskaitė V; Navakauskienė R
Eur J Pharmacol; 2017 Mar; 799():143-153. PubMed ID: 28192098
[TBL] [Abstract] [Full Text] [Related]
11. Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.
Kunz JB; Rausch T; Bandapalli OR; Eilers J; Pechanska P; Schuessele S; Assenov Y; Stütz AM; Kirschner-Schwabe R; Hof J; Eckert C; von Stackelberg A; Schrappe M; Stanulla M; Koehler R; Avigad S; Elitzur S; Handgretinger R; Benes V; Weischenfeldt J; Korbel JO; Muckenthaler MU; Kulozik AE
Haematologica; 2015 Nov; 100(11):1442-50. PubMed ID: 26294725
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12. EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches.
D'Angelo V; Iannotta A; Ramaglia M; Lombardi A; Zarone MR; Desiderio V; Affinita MC; Pecoraro G; Di Martino M; Indolfi P; Casale F; Caraglia M
J Exp Clin Cancer Res; 2015 Aug; 34(1):83. PubMed ID: 26268310
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13. ARE/suz12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells.
Zu B; Shi Y; Xu M; You G; Huang Z; Gao M; Feng W
J Exp Clin Cancer Res; 2015 May; 34(1):56. PubMed ID: 26017281
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14. Epigenetic and molecular mechanisms underlying the antileukemic activity of the histone deacetylase inhibitor belinostat in human acute promyelocytic leukemia cells.
Savickiene J; Treigyte G; Valiuliene G; Stirblyte I; Navakauskiene R
Anticancer Drugs; 2014 Sep; 25(8):938-49. PubMed ID: 24800886
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15. ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells.
Mochmann LH; Neumann M; von der Heide EK; Nowak V; Kühl AA; Ortiz-Tanchez J; Bock J; Hofmann WK; Baldus CD
Oncotarget; 2014 Jan; 5(2):351-62. PubMed ID: 24504051
[TBL] [Abstract] [Full Text] [Related]
16. DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T; Rohde C; Hebestreit K; Klein HU; Göllner S; Schulze I; Lerdrup M; Dietrich N; Agrawal-Singh S; Witten A; Stoll M; Lengfelder E; Hofmann WK; Schlenke P; Büchner T; Hansen K; Berdel WE; Rosenbauer F; Dugas M; Müller-Tidow C
Blood; 2013 Jan; 121(1):178-87. PubMed ID: 23152544
[TBL] [Abstract] [Full Text] [Related]
17. Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia.
Beekman R; Valkhof MG; Sanders MA; van Strien PM; Haanstra JR; Broeders L; Geertsma-Kleinekoort WM; Veerman AJ; Valk PJ; Verhaak RG; Löwenberg B; Touw IP
Blood; 2012 May; 119(22):5071-7. PubMed ID: 22371884
[TBL] [Abstract] [Full Text] [Related]
18. Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring.
Xu F; Li X; Wu L; Zhang Q; Yang R; Yang Y; Zhang Z; He Q; Chang C
Ann Hematol; 2011 Jun; 90(6):643-53. PubMed ID: 21125401
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19. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
Fiskus W; Wang Y; Sreekumar A; Buckley KM; Shi H; Jillella A; Ustun C; Rao R; Fernandez P; Chen J; Balusu R; Koul S; Atadja P; Marquez VE; Bhalla KN
Blood; 2009 Sep; 114(13):2733-43. PubMed ID: 19638619
[TBL] [Abstract] [Full Text] [Related]
20. Regulation of CD11b transcription by decreasing PRC2 and increased acH4 level during ATRA-induced HL-60 differentiation.
Tang H; Chen F; Tan Q; Tan S; Liu L; Zhang F
Acta Biochim Biophys Sin (Shanghai); 2009 Jul; 41(7):588-93. PubMed ID: 19578722
[TBL] [Abstract] [Full Text] [Related]
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