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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND SYK, P43405, 6850, ENSG00000165025
347 results:

  • 1. Spleen tyrosine kinase (syk): an emerging target for the assemblage of small molecule antitumor agents.
    Kaur C; Thakur A; Liou KC; Rao NV; Nepali K
    Expert Opin Investig Drugs; 2024 Sep; 33(9):897-914. PubMed ID: 39096234
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. First-in-class inhibitor of HSP110 blocks BCR activation through syk phosphorylation in diffuse large B-cell lymphoma.
    Gibouin VC; Durand M; Boudesco C; Hermetet F; Nozickova K; Chassagne-Clement C; Abdelwahed M; Klener P; Garrido C; Jego G
    Leukemia; 2024 Aug; 38(8):1742-1750. PubMed ID: 38906964
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. [Research Progress of Targeted Therapy for Chronic Lymphocytic leukemia/Small Lymphocytic Lymphoma --Review].
    Chen D; Wang MY; Tian C
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Apr; 32(2):643-646. PubMed ID: 38660880
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression.
    Wang J; Wang C; Hu A; Yu K; Kuang Y; Gajendran B; Zacksenhaus E; Sample KM; Xiao X; Liu W; Ben-David Y
    BMC Cancer; 2024 Mar; 24(1):326. PubMed ID: 38461240
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18.
    Díaz-Alvarez L; Martínez-Sánchez ME; Gray E; Pérez-Figueroa E; Ortega E
    Biomolecules; 2023 Oct; 13(10):. PubMed ID: 37892170
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome.
    Wagner A; Rouleau M; Villeneuve L; Le T; Peltier C; Allain ÉP; Beaudoin C; Tremblay S; Courtier F; Nguyen Van Long F; Laverdière I; Lévesque É; Banerji V; Vanura K; Guillemette C
    Cells; 2023 May; 12(9):. PubMed ID: 37174695
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targeting and Monitoring Acute Myeloid Leukaemia with Nucleophosmin-1 (
    Chin L; Wong CYG; Gill H
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36834572
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ArtinM Cytotoxicity in B Cells Derived from Non-Hodgkin's Lymphoma Depends on syk and Src Family Kinases.
    Barboza BR; Thomaz SMO; Junior AC; Espreafico EM; Miyamoto JG; Tashima AK; Camacho MF; Zelanis A; Roque-Barreira MC; da Silva TA
    Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674590
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Heterogeneity of Patient-Derived Acute Myeloid leukemia Cells Subjected to syk In Vitro Inhibition.
    Brattås MK; Hemsing AL; Rye KP; Hatfield KJ; Reikvam H
    Int J Mol Sci; 2022 Nov; 23(23):. PubMed ID: 36499034
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Recent advances in understanding spleen tyrosine kinase (syk) in human biology and disease, with a focus on fostamatinib.
    Cooper N; Ghanima W; Hill QA; Nicolson PL; Markovtsov V; Kessler C
    Platelets; 2023 Dec; 34(1):2131751. PubMed ID: 36331249
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Population Pharmacokinetics of Mivavotinib (TAK-659), a Dual Spleen Tyrosine Kinase and FMS-Like Tyrosine Kinase 3 Inhibitor, in Patients With Advanced Solid Tumors or Hematologic Malignancies.
    Li C; Watson K; Wang S; Diderichsen PM; Gupta N
    J Clin Pharmacol; 2023 Mar; 63(3):326-337. PubMed ID: 36309821
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibitors of the effector phase in food allergy.
    Suber J; Zhang Y; Ye P; Guo R; Burks AW; Kulis MD; Smith SA; Iweala OI
    Front Immunol; 2022; 13():974374. PubMed ID: 36248809
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Targeting lipid-protein interaction to treat syk-mediated acute myeloid leukemia.
    Singaram I; Sharma A; Pant S; Lihan M; Park MJ; Pergande M; Buwaneka P; Hu Y; Mahmud N; Kim YM; Cologna S; Gevorgyan V; Khan I; Tajkhorshid E; Cho W
    Nat Chem Biol; 2023 Feb; 19(2):239-250. PubMed ID: 36229686
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A phase Ib trial of mivavotinib (TAK-659), a dual syk/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia.
    Pratz KW; Kaplan J; Levy M; Bixby D; Burke PW; Erba H; Wise-Draper TM; Roboz GJ; Papadantonakis N; Rajkhowa T; Hernandez D; Dobler I; Gregory RC; Li C; Wang S; Stumpo K; Kannan K; Miao H; Levis M
    Haematologica; 2023 Mar; 108(3):705-716. PubMed ID: 36226495
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CD93 promotes acute myeloid leukemia development and is a potential therapeutic target.
    Jia J; Liu B; Wang D; Wang X; Song L; Ren Y; Guo Z; Ma K; Cui C
    Exp Cell Res; 2022 Nov; 420(2):113361. PubMed ID: 36152731
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid leukemia through Suppression of Stemness.
    Liu ACH; Cathelin S; Yang Y; Dai DL; Ayyathan DM; Hosseini M; Minden MD; Tierens A; Chan SM
    Cancer Res; 2022 Dec; 82(23):4325-4339. PubMed ID: 36150062
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells.
    Arthur R; Wathen A; Lemm EA; Stevenson FK; Forconi F; Linley AJ; Steele AJ; Packham G; Valle-Argos B
    Cell Signal; 2022 Aug; 96():110358. PubMed ID: 35597428
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Modeling the B-cell receptor signaling on single cell level reveals a stable network circuit topology between nonmalignant B cells and chronic lymphocytic leukemia cells and between untreated cells and cells treated with kinase inhibitors.
    Wolf C; Maus C; Persicke MRO; Filarsky K; Tausch E; Schneider C; Döhner H; Stilgenbauer S; Lichter P; Höfer T; Mertens D
    Int J Cancer; 2022 Sep; 151(5):783-796. PubMed ID: 35527719
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. syk and ZAP70 kinases in autoimmunity and lymphoid malignancies.
    Leveille E; Chan LN; Mirza AS; Kume K; Müschen M
    Cell Signal; 2022 Jun; 94():110331. PubMed ID: 35398488
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic Inflammation.
    Wang HN; Xiang QA; Lin HH; Chen JN; Guo WJ; Guo WM; Yue XN; Zhao ZF; Ji K; Chen JJ
    Molecules; 2022 Feb; 27(5):. PubMed ID: 35268679
    [TBL] [Abstract] [Full Text] [Related]  


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