Terms: = Leukemia AND TCF7L2, ENSG00000148737, 6934, TCF-4
26 results:
1. Preclinical efficacy of targeting epigenetic mechanisms in AML with 3q26 lesions and EVI1 overexpression.
Birdwell CE; Fiskus W; Kadia TM; Mill CP; Sasaki K; Daver N; DiNardo CD; Pemmaraju N; Borthakur G; Davis JA; Das K; Sharma S; Horrigan S; Ruan X; Su X; Khoury JD; Kantarjian H; Bhalla KN
Leukemia; 2024 Mar; 38(3):545-556. PubMed ID: 38086946
[TBL] [Abstract] [Full Text] [Related]
2. A CD56- immunoblastoid variant of blastic plasmacytoid dendritic cell neoplasm.
Aran BM; Duran J; Whittemore D; Gru AA
J Cutan Pathol; 2024 Jan; 51(1):40-44. PubMed ID: 37612885
[TBL] [Abstract] [Full Text] [Related]
3. The β-catenin-LINC00183-miR-371b-5p-Smad2/LEF1 axis promotes adult T-cell lymphoblastic lymphoma progression and chemoresistance.
Huang WJ; Guo SB; Shi H; Li XL; Zhu Y; Li M; Song LY; Yu RM; Cai QQ; Tian XP
J Exp Clin Cancer Res; 2023 Apr; 42(1):105. PubMed ID: 37106379
[TBL] [Abstract] [Full Text] [Related]
4. Visinin-like 1, a novel target gene of the Wnt/β-catenin signaling pathway, is involved in apoptosis resistance in colorectal cancer.
Tage H; Yamaguchi K; Nakagawa S; Kasuga S; Takane K; Furukawa Y; Ikenoue T
Cancer Med; 2023 Jun; 12(12):13426-13437. PubMed ID: 37096864
[TBL] [Abstract] [Full Text] [Related]
5. Integrated single-cell transcriptome analysis of CD34 + enriched leukemic stem cells revealed intra- and inter-patient transcriptional heterogeneity in pediatric acute myeloid leukemia.
Thakral D; Singh VK; Gupta R; Jha N; Khan A; Kaur G; Rai S; Kumar V; Supriya M; Bakhshi S; Seth R
Ann Hematol; 2023 Jan; 102(1):73-87. PubMed ID: 36527458
[TBL] [Abstract] [Full Text] [Related]
6. Embryonic Program Activated during Blast Crisis of Chronic Myelogenous leukemia (CML) Implicates a tcf7l2 and MYC Cooperative Chromatin Binding.
Desterke C; Hugues P; Hwang JW; Bennaceur-Griscelli A; Turhan AG
Int J Mol Sci; 2020 Jun; 21(11):. PubMed ID: 32517078
[TBL] [Abstract] [Full Text] [Related]
7. Mechanistic basis and efficacy of targeting the β-catenin-tcf7l2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors.
Saenz DT; Fiskus W; Mill CP; Perera D; Manshouri T; Lara BH; Karkhanis V; Sharma S; Horrigan SK; Bose P; Kadia TM; Masarova L; DiNardo CD; Borthakur G; Khoury JD; Takahashi K; Bhaskara S; Lin CY; Green MR; Coarfa C; Crews CM; Verstovsek S; Bhalla KN
Blood; 2020 Apr; 135(15):1255-1269. PubMed ID: 32068780
[TBL] [Abstract] [Full Text] [Related]
8. MicroRNA-124 represses wound healing by targeting SERP1 and inhibiting the Wnt/β-catenin pathway.
Zhang G; Song K; Yan H
Adv Clin Exp Med; 2019 Jun; 28(6):711-718. PubMed ID: 30740945
[TBL] [Abstract] [Full Text] [Related]
9. Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML.
Saenz DT; Fiskus W; Manshouri T; Mill CP; Qian Y; Raina K; Rajapakshe K; Coarfa C; Soldi R; Bose P; Borthakur G; Kadia TM; Khoury JD; Masarova L; Nowak AJ; Sun B; Saenz DN; Kornblau SM; Horrigan S; Sharma S; Qiu P; Crews CM; Verstovsek S; Bhalla KN
Leukemia; 2019 Jun; 33(6):1373-1386. PubMed ID: 30575820
[TBL] [Abstract] [Full Text] [Related]
10. tcf7l2 activated HOXA-AS2 decreased the glucocorticoid sensitivity in acute lymphoblastic leukemia through regulating HOXA3/EGFR/Ras/Raf/MEK/ERK pathway.
Zhao Q; Zhao S; Li J; Zhang H; Qian C; Wang H; Liu J; Zhao Y
Biomed Pharmacother; 2019 Jan; 109():1640-1649. PubMed ID: 30551418
[TBL] [Abstract] [Full Text] [Related]
11. Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9.
Zhang LS; Kang X; Lu J; Zhang Y; Wu X; Wu G; Zheng J; Tuladhar R; Shi H; Wang Q; Morlock L; Yao H; Huang LJ; Maire P; Kim J; Williams N; Xu J; Chen C; Zhang CC; Lum L
EBioMedicine; 2019 Jan; 39():145-158. PubMed ID: 30528456
[TBL] [Abstract] [Full Text] [Related]
12. Molecular mechanisms of breast cancer metastasis by gene expression profile analysis.
Zheng T; Wang A; Hu D; Wang Y
Mol Med Rep; 2017 Oct; 16(4):4671-4677. PubMed ID: 28791367
[TBL] [Abstract] [Full Text] [Related]
13. β-catenin induces expression of prohibitin gene in acute leukemic cells.
Kim DM; Jang H; Shin MG; Kim JH; Shin SM; Min SH; Kim IC
Oncol Rep; 2017 Jun; 37(6):3201-3208. PubMed ID: 28440457
[TBL] [Abstract] [Full Text] [Related]
14. Highly Expressed Antisense Noncoding RNA in the INK4 Locus Promotes Growth and Invasion of Renal Clear Carcinoma Cells via the β-Catenin Pathway.
Li Q; Tian Y; Hu G; Liang Y; Bai W; Li H
Oncol Res; 2017 Sep; 25(8):1373-1382. PubMed ID: 28251886
[TBL] [Abstract] [Full Text] [Related]
15. [Expression of ICAT and Wnt signaling-related proteins in the monocytic differentiation of HL-60 cells induced by a new steroidal drug NSC67657].
Wang JS; Wang WJ; Wang T; Zhang Y
Zhonghua Zhong Liu Za Zhi; 2016 Apr; 38(4):246-51. PubMed ID: 27087369
[TBL] [Abstract] [Full Text] [Related]
16. Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.
Fiskus W; Sharma S; Saha S; Shah B; Devaraj SG; Sun B; Horrigan S; Leveque C; Zu Y; Iyer S; Bhalla KN
Leukemia; 2015 Jun; 29(6):1267-78. PubMed ID: 25482131
[TBL] [Abstract] [Full Text] [Related]
17. Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.
Chen C; Bartenhagen C; Gombert M; Okpanyi V; Binder V; Röttgers S; Bradtke J; Teigler-Schlegel A; Harbott J; Ginzel S; Thiele R; Fischer U; Dugas M; Hu J; Borkhardt A
Genes Chromosomes Cancer; 2013 Jun; 52(6):564-79. PubMed ID: 23508829
[TBL] [Abstract] [Full Text] [Related]
18. Bcr-Abl oncogene stimulates Jab1 expression via cooperative interaction of β-catenin and STAT1 in chronic myeloid leukemia cells.
Yang KT; Wang MC; Chen JY; Hsu MC; Hung WC
J Cell Physiol; 2011 Nov; 226(11):2849-56. PubMed ID: 21935931
[TBL] [Abstract] [Full Text] [Related]
19. CREBBP mutations in relapsed acute lymphoblastic leukaemia.
Mullighan CG; Zhang J; Kasper LH; Lerach S; Payne-Turner D; Phillips LA; Heatley SL; Holmfeldt L; Collins-Underwood JR; Ma J; Buetow KH; Pui CH; Baker SD; Brindle PK; Downing JR
Nature; 2011 Mar; 471(7337):235-9. PubMed ID: 21390130
[TBL] [Abstract] [Full Text] [Related]
20. JS-K, a nitric oxide-releasing prodrug, modulates ß-catenin/TCF signaling in leukemic Jurkat cells: evidence of an S-nitrosylated mechanism.
Nath N; Chattopadhyay M; Pospishil L; Cieciura LZ; Goswami S; Kodela R; Saavedra JE; Keefer LK; Kashfi K
Biochem Pharmacol; 2010 Dec; 80(11):1641-9. PubMed ID: 20797387
[TBL] [Abstract] [Full Text] [Related]
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