Terms: = Leukemia AND TLX3, O43711, 30012, ENSG00000164438, HOX11L2, RNX AND Treatment
24 results:
1. Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma.
De Coninck S; De Smedt R; Lintermans B; Reunes L; Kosasih HJ; Reekmans A; Brown LM; Van Roy N; Palhais B; Roels J; Van der Linden M; Van Dorpe J; Ntziachristos P; Van Delft FW; Mansour MR; Pieters T; Lammens T; De Moerloose B; De Bock CE; Goossens S; Van Vlierberghe P
Haematologica; 2024 May; 109(5):1373-1384. PubMed ID: 37941480
[TBL] [Abstract] [Full Text] [Related]
2. [Characteristics and prognostic effects of NOTCH1/FBXW7 gene mutations in T-cell acute lymphoblastic leukemia patients].
Wu CY; Li YL; Dong XY; Yang SW; Shang BJ; Zhang L; Cheng W; Zhang L; Zhu ZM
Zhonghua Yi Xue Za Zhi; 2022 Jul; 102(25):1910-1917. PubMed ID: 35768390
[No Abstract] [Full Text] [Related]
3. Effect of Mimic Hypoxia on the Proliferation and Expression of miR-27a, miR-9, miR-370 and their Target Genes in MOLT-4 and KG1a Cell Lines.
Emaogolizadeh Gurd Tapeh B; Mohammadi A; Alivand MR; Solali S
Asian Pac J Cancer Prev; 2021 Jun; 22(6):1975-1984. PubMed ID: 34181359
[TBL] [Abstract] [Full Text] [Related]
4. Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.
Touzart A; Mayakonda A; Smith C; Hey J; Toth R; Cieslak A; Andrieu GP; Tran Quang C; Latiri M; Ghysdael J; Spicuglia S; Dombret H; Ifrah N; Macintyre E; Lutsik P; Boissel N; Plass C; Asnafi V
Sci Transl Med; 2021 May; 13(595):. PubMed ID: 34039737
[TBL] [Abstract] [Full Text] [Related]
5. tlx3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma.
Wang C; Dou C; Wang Y; Liu Z; Roberts L; Zheng X
Int J Biol Sci; 2019; 15(8):1696-1711. PubMed ID: 31360112
[TBL] [Abstract] [Full Text] [Related]
6. Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic leukemia.
Vanden Bempt M; Demeyer S; Broux M; De Bie J; Bornschein S; Mentens N; Vandepoel R; Geerdens E; Radaelli E; Bornhauser BC; Kulozik AE; Meijerink JP; Bourquin JP; de Bock CE; Cools J
Cancer Cell; 2018 Aug; 34(2):271-285.e7. PubMed ID: 30107177
[TBL] [Abstract] [Full Text] [Related]
7. Immunophenotyping with CD135 and CD117 predicts the FLT3, IL-7R and tlx3 gene mutations in childhood T-cell acute leukemia.
Noronha EP; Andrade FG; Zampier C; de Andrade CF; Terra-Granado E; Pombo-de-Oliveira MS;
Blood Cells Mol Dis; 2016 Mar; 57():74-80. PubMed ID: 26852660
[TBL] [Abstract] [Full Text] [Related]
8. Newly diagnosed acute lymphoblastic leukemia in China (I): abnormal genetic patterns in 1346 childhood and adult cases and their comparison with the reports from Western countries.
Chen B; Wang YY; Shen Y; Zhang WN; He HY; Zhu YM; Chen HM; Gu CH; Fan X; Chen JM; Cao Q; Yang G; Jiang CL; Weng XQ; Zhang XX; Xiong SM; Shen ZX; Jiang H; Gu LJ; Chen Z; Mi JQ; Chen SJ
Leukemia; 2012 Jul; 26(7):1608-16. PubMed ID: 22382891
[TBL] [Abstract] [Full Text] [Related]
9. Aberrant DNA methylation of T-cell leukemia, homeobox 3 modulates cisplatin sensitivity in bladder cancer.
Tada Y; Yokomizo A; Shiota M; Tsunoda T; Plass C; Naito S
Int J Oncol; 2011 Sep; 39(3):727-33. PubMed ID: 21617853
[TBL] [Abstract] [Full Text] [Related]
10. Successful treatment of a child with T/myeloid acute bilineal leukemia associated with tlx3/BCL11B fusion and 9q deletion.
Oliveira JL; Kumar R; Khan SP; Law ME; Erickson-Johnson M; Oliveira AM; Ketterling RP; Dogan A
Pediatr Blood Cancer; 2011 Mar; 56(3):467-9. PubMed ID: 21225930
[TBL] [Abstract] [Full Text] [Related]
11. Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia.
Meijerink JP
Best Pract Res Clin Haematol; 2010 Sep; 23(3):307-18. PubMed ID: 21112032
[TBL] [Abstract] [Full Text] [Related]
12. NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
Zuurbier L; Homminga I; Calvert V; te Winkel ML; Buijs-Gladdines JG; Kooi C; Smits WK; Sonneveld E; Veerman AJ; Kamps WA; Horstmann M; Petricoin EF; Pieters R; Meijerink JP
Leukemia; 2010 Dec; 24(12):2014-22. PubMed ID: 20861909
[TBL] [Abstract] [Full Text] [Related]
13. ABL1 rearrangements in T-cell acute lymphoblastic leukemia.
Hagemeijer A; Graux C
Genes Chromosomes Cancer; 2010 Apr; 49(4):299-308. PubMed ID: 20073070
[TBL] [Abstract] [Full Text] [Related]
14. NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.
Nagel S; Venturini L; Przybylski GK; Grabarczyk P; Meyer C; Kaufmann M; Battmer K; Schmidt CA; Drexler HG; Scherr M; Macleod RA
BMC Cancer; 2009 Oct; 9():371. PubMed ID: 19835636
[TBL] [Abstract] [Full Text] [Related]
15. Prognostic relevance of tlx3 (hox11l2) expression in childhood T-cell acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing early and late re-intensification elements.
Attarbaschi A; Pisecker M; Inthal A; Mann G; Janousek D; Dworzak M; Pötschger U; Ullmann R; Schrappe M; Gadner H; Haas OA; Panzer-Grümayer R; Strehl S;
Br J Haematol; 2010 Jan; 148(2):293-300. PubMed ID: 19821827
[TBL] [Abstract] [Full Text] [Related]
16. Impact of genotype on survival of children with T-cell acute lymphoblastic leukemia treated according to the French protocol FRALLE-93: the effect of tlx3/hox11l2 gene expression on outcome.
Ballerini P; Landman-Parker J; Cayuela JM; Asnafi V; Labopin M; Gandemer V; Perel Y; Michel G; Leblanc T; Schmitt C; Fasola S; Hagemejier A; Sigaux F; Auclerc MF; Douay L; Leverger G; Baruchel A
Haematologica; 2008 Nov; 93(11):1658-65. PubMed ID: 18835836
[TBL] [Abstract] [Full Text] [Related]
17. Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant hox11l2 expression: experience of the German multicenter ALL study group.
Baak U; Gökbuget N; Orawa H; Schwartz S; Hoelzer D; Thiel E; Burmeister T;
Leukemia; 2008 Jun; 22(6):1154-60. PubMed ID: 18368072
[TBL] [Abstract] [Full Text] [Related]
18. Activation of tlx3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.
Nagel S; Scherr M; Kel A; Hornischer K; Crawford GE; Kaufmann M; Meyer C; Drexler HG; MacLeod RA
Cancer Res; 2007 Feb; 67(4):1461-71. PubMed ID: 17308084
[TBL] [Abstract] [Full Text] [Related]
19. High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults.
Baldus CD; Burmeister T; Martus P; Schwartz S; Gökbuget N; Bloomfield CD; Hoelzer D; Thiel E; Hofmann WK
J Clin Oncol; 2006 Oct; 24(29):4714-20. PubMed ID: 16954520
[TBL] [Abstract] [Full Text] [Related]
20. Impact of TCR status and genotype on outcome in adult T-cell acute lymphoblastic leukemia: a LALA-94 study.
Asnafi V; Buzyn A; Thomas X; Huguet F; Vey N; Boiron JM; Reman O; Cayuela JM; Lheritier V; Vernant JP; Fiere D; Macintyre E; Dombret H
Blood; 2005 Apr; 105(8):3072-8. PubMed ID: 15637138
[TBL] [Abstract] [Full Text] [Related]
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