Terms: = Leukemia AND TOP2A, TOP2, TP2A AND Treatment
29 results:
1. Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/top2a axis.
Zhang B; Li J; Wang Y; Liu X; Yang X; Liao Z; Deng S; Deng Y; Zhou Z; Tian Y; Wei W; Meng J; Hu Y; Wan C; Zhang Z; Huang F; Wen L; Wu B; Sun Y; Li Y; Yang K
Cell Death Differ; 2024 Mar; 31(3):309-321. PubMed ID: 38287116
[TBL] [Abstract] [Full Text] [Related]
2. ATM inhibitor KU60019 synergistically sensitizes lung cancer cells to topoisomerase II poisons by multiple mechanisms.
Shu J; Wang X; Yang X; Zhao G
Sci Rep; 2023 Jan; 13(1):882. PubMed ID: 36650267
[TBL] [Abstract] [Full Text] [Related]
3. Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML.
Nguyen NHK; Rafiee R; Tagmount A; Sobh A; Loguinov A; de Jesus Sosa AK; Elsayed AH; Gbadamosi M; Seligson N; Cogle CR; Rubnitz J; Ribeiro R; Downing J; Cao X; Pounds SB; Vulpe CD; Lamba JK
Blood Adv; 2023 May; 7(9):1769-1783. PubMed ID: 36111891
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4. The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity
Klausz K; Kellner C; Gehlert CL; Krohn S; Wilcken H; Floerkemeier I; Günther A; Bauerschlag DO; Clement B; Gramatzki M; Peipp M
Mol Cancer Ther; 2022 Jan; 21(1):70-78. PubMed ID: 34725192
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5. Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.
Atkin ND; Raimer HM; Wang Z; Zang C; Wang YH
Genes Chromosomes Cancer; 2021 Dec; 60(12):808-821. PubMed ID: 34405474
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6. Chromatin regulators mediate anthracycline sensitivity in breast cancer.
Seoane JA; Kirkland JG; Caswell-Jin JL; Crabtree GR; Curtis C
Nat Med; 2019 Nov; 25(11):1721-1727. PubMed ID: 31700186
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7. Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility.
Atkin ND; Raimer HM; Wang YH
Genes (Basel); 2019 Oct; 10(10):. PubMed ID: 31614754
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8. Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology.
Ahmed SM; Dröge P
Mol Oncol; 2019 Oct; 13(10):2062-2078. PubMed ID: 31271486
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9. Genome-wide top2a DNA cleavage is biased toward translocated and highly transcribed loci.
Yu X; Davenport JW; Urtishak KA; Carillo ML; Gosai SJ; Kolaris CP; Byl JAW; Rappaport EF; Osheroff N; Gregory BD; Felix CA
Genome Res; 2017 Jul; 27(7):1238-1249. PubMed ID: 28385713
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10. Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy.
Atwal M; Lishman EL; Austin CA; Cowell IG
Mol Pharmacol; 2017 Jan; 91(1):49-57. PubMed ID: 27974636
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11. Pathways of cardiac toxicity: comparison between chemotherapeutic drugs doxorubicin and mitoxantrone.
Damiani RM; Moura DJ; Viau CM; Caceres RA; Henriques JAP; Saffi J
Arch Toxicol; 2016 Sep; 90(9):2063-2076. PubMed ID: 27342245
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12. Differential Targeting of Human Topoisomerase II Isoforms with Small Molecules.
Mariani A; Bartoli A; Atwal M; Lee KC; Austin CA; Rodriguez R
J Med Chem; 2015 Jun; 58(11):4851-6. PubMed ID: 25945730
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13. Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression.
Nair SV; Ziaullah ; Rupasinghe HP
PLoS One; 2014; 9(9):e107149. PubMed ID: 25229655
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14. Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells.
Hatfield KJ; Reikvam H; Bruserud Ø
Expert Opin Ther Targets; 2014 Nov; 18(11):1237-51. PubMed ID: 25200484
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15. The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.
Smith KA; Cowell IG; Zhang Y; Sondka Z; Austin CA
Genes Chromosomes Cancer; 2014 Feb; 53(2):117-28. PubMed ID: 24327541
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16. FBXW7 mediates chemotherapeutic sensitivity and prognosis in NSCLCs.
Yokobori T; Yokoyama Y; Mogi A; Endoh H; Altan B; Kosaka T; Yamaki E; Yajima T; Tomizawa K; Azuma Y; Onozato R; Miyazaki T; Tanaka S; Kuwano H
Mol Cancer Res; 2014 Jan; 12(1):32-7. PubMed ID: 24165483
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17. Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
Tamaichi H; Sato M; Porter AC; Shimizu T; Mizutani S; Takagi M
Cancer Sci; 2013 Feb; 104(2):178-84. PubMed ID: 23163762
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18. Lasonolide A, a potent and reversible inducer of chromosome condensation.
Zhang YW; Ghosh AK; Pommier Y
Cell Cycle; 2012 Dec; 11(23):4424-35. PubMed ID: 23159859
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19. Sensitivity to top2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L.
Lu H; Hallstrom TC
PLoS One; 2012; 7(8):e42921. PubMed ID: 22900064
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20. High top2B/top2a expression ratio at diagnosis correlates with favourable outcome for standard chemotherapy in acute myeloid leukaemia.
Song JH; Kweon SH; Kim HJ; Lee TH; Min WS; Kim HJ; Kim YK; Hwang SY; Kim TS
Br J Cancer; 2012 Jun; 107(1):108-15. PubMed ID: 22627319
[TBL] [Abstract] [Full Text] [Related]
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