BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND WAS, P42768, 7454, ENSG00000015285, WASP, THC, IMD2 AND Treatment
25 results:

  • 1. Role of Wiskott Aldrich syndrome protein in haematological malignancies: genetics, molecular mechanisms and therapeutic strategies.
    R P; Shanmugam G; Rakshit S; Sarkar K
    Pathol Res Pract; 2024 Jan; 253():155026. PubMed ID: 38118219
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Investigating the Effects of a Synthetic Cannabinoid on the Pathogenesis of leukemia and Leukemic Stem Cells: A New Therapeutic Approach.
    Salcin H; Goker Bagca B; Alcitepe I; Biray Avci C; Aslan R; Annette Akgur S; Tezcanli Kaymaz B
    Cannabis Cannabinoid Res; 2024 Feb; 9(1):212-222. PubMed ID: 35834597
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia.
    Garitano-Trojaola A; Sancho A; Götz R; Eiring P; Walz S; Jetani H; Gil-Pulido J; Da Via MC; Teufel E; Rhodes N; Haertle L; Arellano-Viera E; Tibes R; Rosenwald A; Rasche L; Hudecek M; Sauer M; Groll J; Einsele H; Kraus S; Kortüm MK
    Commun Biol; 2021 Jun; 4(1):799. PubMed ID: 34172833
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Glioma pathogenesis-related protein 1 performs dual functions in tumor cells.
    Wang J; Li Z; Yin F; Zhang R; Zhang Y; Wang Z; Sheng X
    Cancer Gene Ther; 2022 Mar; 29(3-4):253-263. PubMed ID: 33742130
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study.
    Ferrua F; Cicalese MP; Galimberti S; Giannelli S; Dionisio F; Barzaghi F; Migliavacca M; Bernardo ME; Calbi V; Assanelli AA; Facchini M; Fossati C; Albertazzi E; Scaramuzza S; Brigida I; Scala S; Basso-Ricci L; Pajno R; Casiraghi M; Canarutto D; Salerio FA; Albert MH; Bartoli A; Wolf HM; Fiori R; Silvani P; Gattillo S; Villa A; Biasco L; Dott C; Culme-Seymour EJ; van Rossem K; Atkinson G; Valsecchi MG; Roncarolo MG; Ciceri F; Naldini L; Aiuti A
    Lancet Haematol; 2019 May; 6(5):e239-e253. PubMed ID: 30981783
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Intense Uptake of Liposomal Curcumin by Multiple Myeloma Cell Lines: Comparison to Normal Lymphocytes, Red Blood Cells and Chronic Lymphocytic leukemia Cells.
    Bolger GT; Licollari A; Bagshaw R; Tan A; Greil R; Vcelar B; Majeed M; Sordillo P
    Anticancer Res; 2019 Mar; 39(3):1161-1168. PubMed ID: 30842145
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. BCR-ABL1-induced downregulation of wasp in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy.
    Pereira WO; De Carvalho DD; Zenteno ME; Ribeiro BF; Jacysyn JF; Sardinha LR; Zanichelli MA; Hamerschlak N; Jones GE; Pagnano KB; Castro FA; Calle Y; Amarante-Mendes GP
    Cell Death Dis; 2017 Oct; 8(10):e3114. PubMed ID: 29022901
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
    Morris EC; Fox T; Chakraverty R; Tendeiro R; Snell K; Rivat C; Grace S; Gilmour K; Workman S; Buckland K; Butler K; Chee R; Salama AD; Ibrahim H; Hara H; Duret C; Mavilio F; Male F; Bushman FD; Galy A; Burns SO; Gaspar HB; Thrasher AJ
    Blood; 2017 Sep; 130(11):1327-1335. PubMed ID: 28716862
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mastoparan is a membranolytic anti-cancer peptide that works synergistically with gemcitabine in a mouse model of mammary carcinoma.
    Hilchie AL; Sharon AJ; Haney EF; Hoskin DW; Bally MB; Franco OL; Corcoran JA; Hancock REW
    Biochim Biophys Acta; 2016 Dec; 1858(12):3195-3204. PubMed ID: 27693190
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Knockdown of WAVE1 enhances apoptosis of leukemia cells by downregulating autophagy.
    Zhang Z; Wu B; Chai W; Cao L; Wang Y; Yu Y; Yang L
    Int J Oncol; 2016 Jun; 48(6):2647-56. PubMed ID: 27035872
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [Clinical features and genotype analysis of 132 patients with Wiskott-Aldrich syndrome].
    Li W; Liu D; Zhang X; Ding Y; Zhao X
    Zhonghua Er Ke Za Zhi; 2015 Dec; 53(12):925-30. PubMed ID: 26887548
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Gene therapy for primary immunodeficiencies: current status and future prospects.
    Qasim W; Gennery AR
    Drugs; 2014 Jun; 74(9):963-9. PubMed ID: 24848753
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.
    Wu JC; Lai CS; Badmaev V; Nagabhushanam K; Ho CT; Pan MH
    Mol Nutr Food Res; 2011 Nov; 55(11):1646-54. PubMed ID: 21928294
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. [Expression of WAVE1 in childhood acute lymphocytic leukemia and in the apoptosis of Jurkat cells induced by adriamycin].
    Wang Z; Hu T; Cao LZ; Kang R; Zhao MY; Yu Y; Xu WQ
    Zhongguo Dang Dai Er Ke Za Zhi; 2008 Oct; 10(5):620-4. PubMed ID: 18947485
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.
    Jia W; Hegde VL; Singh NP; Sisco D; Grant S; Nagarkatti M; Nagarkatti PS
    Mol Cancer Res; 2006 Aug; 4(8):549-62. PubMed ID: 16908594
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Induction of intracellular calcium elevation by Delta9-tetrahydrocannabinol in T cells involves TRPC1 channels.
    Rao GK; Kaminski NE
    J Leukoc Biol; 2006 Jan; 79(1):202-13. PubMed ID: 16244107
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (thc)-induced apoptosis of Jurkat cells.
    Lombard C; Nagarkatti M; Nagarkatti PS
    Leuk Res; 2005 Aug; 29(8):915-22. PubMed ID: 15978942
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells.
    Rao GK; Zhang W; Kaminski NE
    J Leukoc Biol; 2004 May; 75(5):884-92. PubMed ID: 14966196
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
    McKallip RJ; Lombard C; Fisher M; Martin BR; Ryu S; Grant S; Nagarkatti PS; Nagarkatti M
    Blood; 2002 Jul; 100(2):627-34. PubMed ID: 12091357
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Long-term survival following non-Hodgkin's lymphoma arising in Wiskott-Aldrich syndrome.
    Gilson D; Taylor RE
    Clin Oncol (R Coll Radiol); 1999; 11(4):283-5. PubMed ID: 10473730
    [TBL] [Abstract] [Full Text] [Related]  


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