BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND WHSC1, 7468, O96028, WHS, TRX5, REIIBP, NSD2, MMSET, MGC176638, KIAA1090, FLJ23286 AND Diagnosis
11 results:

  • 1. nsd2 E1099K drives relapse in pediatric acute lymphoblastic leukemia by disrupting 3D chromatin organization.
    Narang S; Evensen NA; Saliba J; Pierro J; Loh ML; Brown PA; Kolekar P; Mulder H; Shao Y; Easton J; Ma X; Tsirigos A; Carroll WL
    Genome Biol; 2023 Apr; 24(1):64. PubMed ID: 37016431
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
    Tamai M; Kasai S; Akahane K; Thu TN; Kagami K; Komatsu C; Abe M; Watanabe A; Goi K; Miyake K; Inaba T; Takita J; Goto H; Minegishi M; Iwamoto S; Sugita K; Inukai T
    J Steroid Biochem Mol Biol; 2022 Apr; 218():106068. PubMed ID: 35124168
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse.
    Antić Ž; Yu J; Bornhauser BC; Lelieveld SH; van der Ham CG; van Reijmersdal SV; Morgado L; Elitzur S; Bourquin JP; Cazzaniga G; Eckert C; Camós M; Sutton R; Cavé H; Moorman AV; Sonneveld E; Geurts van Kessel A; van Leeuwen FN; Hoogerbrugge PM; Waanders E; Kuiper RP
    Pediatr Blood Cancer; 2022 Jan; 69(1):e29361. PubMed ID: 34597466
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations.
    Antić Ž; Yu J; Van Reijmersdal SV; Van Dijk A; Dekker L; Segerink WH; Sonneveld E; Fiocco M; Pieters R; Hoogerbrugge PM; Van Leeuwen FN; Van Kessel AG; Waanders E; Kuiper RP
    Haematologica; 2021 Dec; 106(12):3046-3055. PubMed ID: 33147938
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The nsd2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context-Dependent Manner in Pediatric Acute Lymphoblastic leukemia.
    Pierro J; Saliba J; Narang S; Sethia G; Saint Fleur-Lominy S; Chowdhury A; Qualls A; Fay H; Kilberg HL; Moriyama T; Fuller TJ; Teachey DT; Schmiegelow K; Yang JJ; Loh ML; Brown PA; Zhang J; Ma X; Tsirigos A; Evensen NA; Carroll WL
    Mol Cancer Res; 2020 Aug; 18(8):1153-1165. PubMed ID: 32332049
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL.
    Jain P; Zhang S; Kanagal-Shamanna R; Ok CY; Nomie K; Gonzalez GN; Gonzalez-Pagan O; Hill HA; Lee HJ; Fayad L; Westin J; Nastoupil L; Hagemeister F; Chen W; Oriabure O; Badillo M; Jiang C; Yixin Y; Li S; Tang G; Yin CC; Patel KP; Medeiros LJ; Nair R; Ahmed S; Iyer SP; Thirumurthi S; Champlin R; Xu G; Tinsu P; Santos D; Wang R; Han G; Zhang J; Song X; Neelapu S; Romaguera J; Futreal A; Flowers C; Fowler N; Wang L; Wang ML
    Blood Adv; 2020 Mar; 4(6):1038-1050. PubMed ID: 32191807
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.
    Li B; Brady SW; Ma X; Shen S; Zhang Y; Li Y; Szlachta K; Dong L; Liu Y; Yang F; Wang N; Flasch DA; Myers MA; Mulder HL; Ding L; Liu Y; Tian L; Hagiwara K; Xu K; Zhou X; Sioson E; Wang T; Yang L; Zhao J; Zhang H; Shao Y; Sun H; Sun L; Cai J; Sun HY; Lin TN; Du L; Li H; Rusch M; Edmonson MN; Easton J; Zhu X; Zhang J; Cheng C; Raphael BJ; Tang J; Downing JR; Alexandrov LB; Zhou BS; Pui CH; Yang JJ; Zhang J
    Blood; 2020 Jan; 135(1):41-55. PubMed ID: 31697823
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Mutational Landscape of Pediatric Acute Lymphoblastic leukemia.
    Ding LW; Sun QY; Tan KT; Chien W; Mayakonda A; Yeoh AEJ; Kawamata N; Nagata Y; Xiao JF; Loh XY; Lin DC; Garg M; Jiang YY; Xu L; Lim SL; Liu LZ; Madan V; Sanada M; Fernández LT; Hema Preethi SS; Lill M; Kantarjian HM; Kornblau SM; Miyano S; Liang DC; Ogawa S; Shih LY; Yang H; Koeffler HP
    Cancer Res; 2017 Jan; 77(2):390-400. PubMed ID: 27872090
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.
    Kunz JB; Rausch T; Bandapalli OR; Eilers J; Pechanska P; Schuessele S; Assenov Y; Stütz AM; Kirschner-Schwabe R; Hof J; Eckert C; von Stackelberg A; Schrappe M; Stanulla M; Koehler R; Avigad S; Elitzur S; Handgretinger R; Benes V; Weischenfeldt J; Korbel JO; Muckenthaler MU; Kulozik AE
    Haematologica; 2015 Nov; 100(11):1442-50. PubMed ID: 26294725
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.
    Ma X; Edmonson M; Yergeau D; Muzny DM; Hampton OA; Rusch M; Song G; Easton J; Harvey RC; Wheeler DA; Ma J; Doddapaneni H; Vadodaria B; Wu G; Nagahawatte P; Carroll WL; Chen IM; Gastier-Foster JM; Relling MV; Smith MA; Devidas M; Guidry Auvil JM; Downing JR; Loh ML; Willman CL; Gerhard DS; Mullighan CG; Hunger SP; Zhang J
    Nat Commun; 2015 Mar; 6():6604. PubMed ID: 25790293
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [Application of FICTION technique to the detection of genetic aberrations in multiple myeloma].
    Wang D; Huang L; Zhang H; Geng Z; Shang Z; Zhou JF; Li CR
    Zhonghua Xue Ye Xue Za Zhi; 2011 Apr; 32(4):226-30. PubMed ID: 21569703
    [TBL] [Abstract] [Full Text] [Related]  


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