Terms: = Leukemia AND WRN, RECQL2, 7486, ENSG00000165392, Q14191, RECQ3
22 results:
1. Design, synthesis and antitumor activity of 2-substituted quinazoline-4-amine derivatives.
Wang M; Yu J; Huang X; Yu G; Liang Q; Cheng S; Meng X; Xu G; Li H; Luo H; Xu B
Bioorg Med Chem; 2024 Mar; 102():117660. PubMed ID: 38442524
[TBL] [Abstract] [Full Text] [Related]
2. Werner helicase mediates the senescence and cell cycle of leukemia cells by regulating DNA repair pathways.
Cui X; Hou J; Wang S; Yu J; Cheng S; Yu L; Song FJ; Luo H
Int J Biol Macromol; 2024 Jan; 255():128305. PubMed ID: 37992942
[TBL] [Abstract] [Full Text] [Related]
3. A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency.
Kato H; Maezawa Y; Nishijima D; Iwamoto E; Takeda J; Kanamori T; Yamaga M; Mishina T; Takeda Y; Izumi S; Hino Y; Nishi H; Ishiko J; Takeuchi M; Kaneko H; Koshizaka M; Mimura N; Kuzuya M; Sakaida E; Takemoto M; Shiraishi Y; Miyano S; Ogawa S; Iwama A; Sanada M; Yokote K
Exp Hematol; 2022 May; 109():11-17. PubMed ID: 35240258
[TBL] [Abstract] [Full Text] [Related]
4. Genes, Proteins, and Biological Pathways Preventing Chromothripsis.
Poot M
Methods Mol Biol; 2018; 1769():231-251. PubMed ID: 29564828
[TBL] [Abstract] [Full Text] [Related]
5. wrn-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells.
Moles R; Bai XT; Chaib-Mezrag H; Nicot C
J Hematol Oncol; 2016 Nov; 9(1):121. PubMed ID: 27829440
[TBL] [Abstract] [Full Text] [Related]
6. Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair.
Castaño J; Herrero AB; Bursen A; González F; Marschalek R; Gutiérrez NC; Menendez P
Oncotarget; 2016 May; 7(21):30440-52. PubMed ID: 27119507
[TBL] [Abstract] [Full Text] [Related]
7. Polymorphisms in DNA repair genes and MDR1 and the risk for non-Hodgkin lymphoma.
Kim HN; Kim NY; Yu L; Kim YK; Lee IK; Yang DH; Lee JJ; Shin MH; Park KS; Choi JS; Kim HJ
Int J Mol Sci; 2014 Apr; 15(4):6703-16. PubMed ID: 24756092
[TBL] [Abstract] [Full Text] [Related]
8. ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.
Fausti F; Di Agostino S; Cioce M; Bielli P; Sette C; Pandolfi PP; Oren M; Sudol M; Strano S; Blandino G
Cell Death Differ; 2013 Nov; 20(11):1498-509. PubMed ID: 23933816
[TBL] [Abstract] [Full Text] [Related]
9. Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies.
Gaymes TJ; Mohamedali AM; Patterson M; Matto N; Smith A; Kulasekararaj A; Chelliah R; Curtin N; Farzaneh F; Shall S; Mufti GJ
Haematologica; 2013 Sep; 98(9):1397-406. PubMed ID: 23349304
[TBL] [Abstract] [Full Text] [Related]
10. Association of GSTT1 polymorphism with acute myeloid leukemia risk is dependent on smoking status.
Kim HN; Kim NY; Yu L; Tran HT; Kim YK; Lee IK; Shin MH; Park KS; Choi JS; Kim HJ
Leuk Lymphoma; 2012 Apr; 53(4):681-7. PubMed ID: 21942242
[TBL] [Abstract] [Full Text] [Related]
11. Promyelocytic leukemia protein interacts with werner syndrome helicase and regulates double-strand break repair in γ-irradiation-induced DNA damage responses.
Liu J; Song Y; Qian J; Liu B; Dong Y; Tian B; Sun Z
Biochemistry (Mosc); 2011 May; 76(5):550-4. PubMed ID: 21639834
[TBL] [Abstract] [Full Text] [Related]
12. BCR/ABL stimulates wrn to promote survival and genomic instability.
Slupianek A; Poplawski T; Jozwiakowski SK; Cramer K; Pytel D; Stoczynska E; Nowicki MO; Blasiak J; Skorski T
Cancer Res; 2011 Feb; 71(3):842-51. PubMed ID: 21123451
[TBL] [Abstract] [Full Text] [Related]
13. Revealing the role of TEL/AML1 for leukemic cell survival by RNAi-mediated silencing.
Zaliova M; Madzo J; Cario G; Trka J
Leukemia; 2011 Feb; 25(2):313-20. PubMed ID: 21109770
[TBL] [Abstract] [Full Text] [Related]
14. Electronic structure and spectro-structural correlations of Fe(III)Zn(II) biomimetics for purple acid phosphatases: relevance to DNA cleavage and cytotoxic activity.
Peralta RA; Bortoluzzi AJ; de Souza B; Jovito R; Xavier FR; Couto RA; Casellato A; Nome F; Dick A; Gahan LR; Schenk G; Hanson GR; de Paula FC; Pereira-Maia EC; de P Machado S; Severino PC; Pich C; Bortolotto T; Terenzi H; Castellano EE; Neves A; Riley MJ
Inorg Chem; 2010 Dec; 49(24):11421-38. PubMed ID: 21080710
[TBL] [Abstract] [Full Text] [Related]
15. Up-regulation of wrn and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks.
Sallmyr A; Tomkinson AE; Rassool FV
Blood; 2008 Aug; 112(4):1413-23. PubMed ID: 18524993
[TBL] [Abstract] [Full Text] [Related]
16. Regulation of wrn protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation.
Li K; Casta A; Wang R; Lozada E; Fan W; Kane S; Ge Q; Gu W; Orren D; Luo J
J Biol Chem; 2008 Mar; 283(12):7590-8. PubMed ID: 18203716
[TBL] [Abstract] [Full Text] [Related]
17. Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.
Vaitiekunaite R; Butkiewicz D; Krześniak M; Przybyłek M; Gryc A; Snietura M; Benedyk M; Harris CC; Rusin M
Mech Ageing Dev; 2007; 128(11-12):650-61. PubMed ID: 17996922
[TBL] [Abstract] [Full Text] [Related]
18. Severe toxicity following induction chemotherapy for acute myelogenous leukemia in a patient with Werner's syndrome.
Seiter K; Qureshi A; Liu D; Galvin-Parton P; Arshad M; Agoliati G; Ahmed T
Leuk Lymphoma; 2005 Jul; 46(7):1091-5. PubMed ID: 16019564
[TBL] [Abstract] [Full Text] [Related]
19. Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
Cheng WH; von Kobbe C; Opresko PL; Fields KM; Ren J; Kufe D; Bohr VA
Mol Cell Biol; 2003 Sep; 23(18):6385-95. PubMed ID: 12944467
[TBL] [Abstract] [Full Text] [Related]
20. Nuclear structure in normal and Bloom syndrome cells.
Yankiwski V; Marciniak RA; Guarente L; Neff NF
Proc Natl Acad Sci U S A; 2000 May; 97(10):5214-9. PubMed ID: 10779560
[TBL] [Abstract] [Full Text] [Related]
[Next]
