Terms: = Leukemia AND XPO1, DKFZp686B1823, 7514, ENSG00000082898, O14980, CRM1
166 results:
1. Genomic and global gene expression profiling in pediatric and young adult acute leukemia with PICALM::MLLT10 Fusion.
Ma J; Liu YC; Voss RK; Ma J; Palagani A; Caldwell E; Rosikiewicz W; Cardenas M; Foy S; Umeda M; Wilkinson MR; Inaba H; Klco JM; Rubnitz JE; Wang L
Leukemia; 2024 May; 38(5):981-990. PubMed ID: 38429501
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2. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
Abla O; Ries RE; Triche T; Gerbing RB; Hirsch B; Raimondi S; Cooper T; Farrar JE; Buteyn N; Harmon LM; Wen H; Deshpande AJ; Kolb EA; Gamis AS; Aplenc R; Alonzo T; Meshinchi S
Blood Adv; 2024 Apr; 8(8):2005-2017. PubMed ID: 38306602
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3. Chronic Lymphocytic leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing.
Grants JM; May C; Bridgers J; Huang S; Gillis S; Meissner B; Boyle M; Ben-Neriah S; Hung S; Duns G; Hilton L; Gerrie AS; Marra M; Kridel R; Sabatini PJB; Steidl C; Scott DW; Karsan A
Clin Chem; 2024 Jan; 70(1):273-284. PubMed ID: 38175592
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4. Enhanced
Nishida Y; Ishizawa J; Ayoub E; Montoya RH; Ostermann LB; Muftuoglu M; Ruvolo VR; Patsilevas T; Scruggs DA; Khazaei S; Mak PY; Tao W; Carter BZ; Boettcher S; Ebert BL; Daver NG; Konopleva M; Seki T; Kojima K; Andreeff M
Sci Adv; 2023 Dec; 9(48):eadh1436. PubMed ID: 38019903
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5. Absence of BTK, BCL2, and PLCG2 Mutations in Chronic Lymphocytic leukemia Relapsing after First-Line Treatment with Fixed-Duration Ibrutinib plus Venetoclax.
Jain N; Croner LJ; Allan JN; Siddiqi T; Tedeschi A; Badoux XC; Eckert K; Cheung LWK; Mukherjee A; Dean JP; Szafer-Glusman E; Seymour JF
Clin Cancer Res; 2024 Feb; 30(3):498-505. PubMed ID: 37955424
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6. Targeting TP53 disruption in chronic lymphocytic leukemia: Current strategies and future directions.
Molica S; Tam C; Allsup D; Polliack A
Hematol Oncol; 2024 Jan; 42(1):e3238. PubMed ID: 37937506
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7. xpo1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression.
Fisher JG; Doyle ADP; Graham LV; Sonar S; Sale B; Henderson I; Del Rio L; Johnson PWM; Landesman Y; Cragg MS; Forconi F; Walker CJ; Khakoo SI; Blunt MD
Leukemia; 2023 Oct; 37(10):2036-2049. PubMed ID: 37528310
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8. Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/crm1 and rearrangement of 3D genome structure.
Oka M; Otani M; Miyamoto Y; Oshima R; Adachi J; Tomonaga T; Asally M; Nagaoka Y; Tanaka K; Toyoda A; Ichikawa K; Morishita S; Isono K; Koseki H; Nakato R; Ohkawa Y; Yoneda Y
Cell Rep; 2023 Aug; 42(8):112884. PubMed ID: 37516964
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9. xpo1 is a new target of homoharringtonine (HHT): Making NPMc
Xue J; Chu P; Gao W; Wang F; Gao Y; Liu S; Kang Z; Yan J; Wang H
Biochem Biophys Res Commun; 2023 Oct; 675():155-161. PubMed ID: 37473530
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10. NPM1-mutated acute myeloid leukemia: New pathogenetic and therapeutic insights and open questions.
Falini B
Am J Hematol; 2023 Sep; 98(9):1452-1464. PubMed ID: 37317978
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11. Azacitidine Is Synergistically Lethal with xpo1 Inhibitor Selinexor in Acute Myeloid leukemia by Targeting xpo1/eIF4E/c-MYC Signaling.
Long H; Hou Y; Li J; Song C; Ge Z
Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047788
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12. NPM1-Mutated Acute Myeloid leukemia: Recent Developments and Open Questions.
Patel SS
Pathobiology; 2024; 91(1):18-29. PubMed ID: 36944324
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13. Covalent targeting the LAS1-NOL9 axis for selective treatment in NPM1 mutant acute myeloid leukemia.
Han Y; Hu A; Qu Y; Xu Q; Wang H; Feng Y; Hu Y; He L; Wu H; Wang X
Pharmacol Res; 2023 Mar; 189():106700. PubMed ID: 36796466
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14. Synthetic lethal targeting of TET2-mutant haematopoietic stem and progenitor cells by xpo1 inhibitors.
Jing CB; Prutsch N; He S; Zimmerman MW; Landesman Y; Look AT
Br J Haematol; 2023 May; 201(3):489-501. PubMed ID: 36746437
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15. Prognostic value and therapeutic targeting of xpo1 in chronic lymphocytic leukemia.
Xu Z; Pan B; Miao Y; Li Y; Qin S; Liang J; Kong Y; Zhang X; Tang J; Xia Y; Zhu H; Wang L; Li J; Wu J; Xu W
Clin Exp Med; 2023 Oct; 23(6):2651-2662. PubMed ID: 36738306
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16. E3 ubiquitin ligase ASB8 promotes selinexor-induced proteasomal degradation of xpo1.
Kwanten B; Deconick T; Walker C; Wang F; Landesman Y; Daelemans D
Biomed Pharmacother; 2023 Apr; 160():114305. PubMed ID: 36731340
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17. Exportin 1-mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma.
Caillot M; Miloudi H; Taly A; Profitós-Pelejà N; Santos JC; Ribeiro ML; Maitre E; Saule S; Roué G; Jardin F; Sola B
Mol Oncol; 2023 Dec; 17(12):2546-2564. PubMed ID: 36727672
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18. Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
Mansouri L; Thorvaldsdottir B; Sutton LA; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodríguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylhä C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larráyoz MJ; Calasanz MJ; Fésüs V; Mátrai Z; Bödör C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazón-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernández-Sánchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Leukemia; 2023 Feb; 37(2):339-347. PubMed ID: 36566271
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19. Current status and future perspectives in targeted therapy of NPM1-mutated AML.
Ranieri R; Pianigiani G; Sciabolacci S; Perriello VM; Marra A; Cardinali V; Pierangeli S; Milano F; Gionfriddo I; Brunetti L; Martelli MP; Falini B
Leukemia; 2022 Oct; 36(10):2351-2367. PubMed ID: 36008542
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20. Addition of the nuclear export inhibitor selinexor to standard intensive treatment for elderly patients with acute myeloid leukemia and high risk myelodysplastic syndrome.
Janssen JJWM; Löwenberg B; Manz M; Biemond BJ; Westerweel PE; Klein SK; Fehr M; Sinnige HAM; Efthymiou A; Legdeur MCJC; Pabst T; Gregor M; van der Poel MWM; Deeren D; Tick LW; Jongen-Lavrencic M; van Obbergh F; Boersma RS; de Weerdt O; Chalandon Y; Heim D; Spertini O; van Sluis G; Graux C; Stüssi G; van Norden Y; Ossenkoppele GJ
Leukemia; 2022 Sep; 36(9):2189-2195. PubMed ID: 35869267
[TBL] [Abstract] [Full Text] [Related]
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