BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND CREBBP, CBP, 1387, ENSG00000005339, RSTS, RTS AND Treatment
37 results:

  • 1. Psilostachyin C reduces malignant properties of hepatocellular carcinoma cells by blocking crebbp-mediated transcription of GATAD2B.
    Jiang K; Ning N; Huang J; Chang Y; Wang R; Ma J
    Funct Integr Genomics; 2024 Apr; 24(2):75. PubMed ID: 38600341
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the cbp/β-catenin inhibitor PRI-724 in patients with liver cirrhosis.
    Yoshida M; Matsuzaki J; Fujita K; Kimura M; Umezu T; Tokuda N; Yamaguchi T; Kuroda M; Ochiya T; Saito Y; Kimura K
    Sci Rep; 2024 Mar; 14(1):6266. PubMed ID: 38491114
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. A multicenter, randomized phase 2 study to establish combinations of cbp501, cisplatin and nivolumab for ≥3rd-line treatment of patients with advanced pancreatic adenocarcinoma.
    Enzler T; Nguyen A; Misleh J; Cline VJ; Johns M; Shumway N; Paulson S; Siegel R; Larson T; Messersmith W; Richards D; Chaves J; Pierce E; Zalupski M; Sahai V; Orr D; Ruste SA; Haun A; Kawabe T
    Eur J Cancer; 2024 Apr; 201():113950. PubMed ID: 38422585
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials?
    Potter GE; Callier V; Shrestha B; Joshi S; Dwivedi A; Silva JC; Laurens MB; Follmann DA; Deye GA
    Malar J; 2023 Dec; 22(1):383. PubMed ID: 38115002
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Association of Age With treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal cancer.
    Meng L; Thapa R; Delgado MG; Gomez MF; Ji R; Knepper TC; Hubbard JM; Wang X; Permuth JB; Kim RD; Laber DA; Xie H
    JAMA Netw Open; 2023 Jun; 6(6):e2320035. PubMed ID: 37358854
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis.
    Qureshi R; Picon-Ruiz M; Sho M; Van Booven D; Nunes de Paiva V; Diaz-Ruano AB; Ince TA; Slingerland J
    Cell Rep; 2022 Nov; 41(7):111672. PubMed ID: 36384125
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Qualitative and quantitative parameters on hepatobiliary phase of gadoxetic acid-enhanced MR imaging for predicting pathological response to preoperative systemic therapy in colorectal liver metastases.
    Gu XL; Cui Y; Wang K; Xing Q; Li XT; Zhu HT; Li ZW; Sun YS
    Eur J Radiol; 2022 Dec; 157():110572. PubMed ID: 36327859
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as cbp Bromodomain Inhibitors for the treatment of Prostate cancer.
    Xiang Q; Wang C; Wu T; Zhang C; Hu Q; Luo G; Hu J; Zhuang X; Zou L; Shen H; Wu X; Zhang Y; Kong X; Liu J; Xu Y
    J Med Chem; 2022 Jan; 65(1):785-810. PubMed ID: 34962793
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Incidence, treatment and Outcome of Patients with Retroperitoneal Soft-Tissue Sarcoma in Switzerland 2005-2015: A Population-Based Analysis.
    Willburger JCF; von Strauss M; Peterson CJ; Glass TR; Kettelhack C
    World J Surg; 2022 Feb; 46(2):461-468. PubMed ID: 34755196
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeting p300/cbp Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism.
    Cai LY; Chen SJ; Xiao SH; Sun QJ; Ding CH; Zheng BN; Zhu XY; Liu SQ; Yang F; Yang YX; Zhou B; Luo C; Zhang X; Xie WF
    Cancer Res; 2021 Feb; 81(4):860-872. PubMed ID: 33361394
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma.
    Gabata R; Harada K; Mizutani Y; Ouchi H; Yoshimura K; Sato Y; Kitao A; Kimura K; Kouji H; Miyashita T; Tajima H; Ohta T
    Anticancer Res; 2020 Sep; 40(9):5211-5219. PubMed ID: 32878809
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.
    Dong P; Wang X; Liu L; Tang W; Ma L; Zeng W; Sun S; Zhang L; Zhang N; Shen X; Janssen HLA; Dong L; Zhang S; Chen S
    J Hepatol; 2020 Dec; 73(6):1446-1459. PubMed ID: 32610114
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Deep learning for identification of critical regions associated with toxicities after liver stereotactic body radiation therapy.
    Ibragimov B; Toesca DAS; Chang DT; Yuan Y; Koong AC; Xing L; Vogelius IR
    Med Phys; 2020 Aug; 47(8):3721-3731. PubMed ID: 32406531
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/cbp signaling pathway.
    Cui Y; Wu X; Lin C; Zhang X; Ye L; Ren L; Chen M; Yang M; Li Y; Li M; Li J; Guan J; Song L
    Oncogene; 2019 Jul; 38(27):5516-5529. PubMed ID: 30936461
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma.
    Dong L; You S; Zhang Q; Osuka S; Devi NS; Kaluz S; Ferguson JH; Yang H; Chen G; Wang B; Grossniklaus HE; Van Meir EG
    Clin Cancer Res; 2019 Apr; 25(7):2206-2218. PubMed ID: 30563937
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review).
    Katoh M
    Int J Mol Med; 2018 Aug; 42(2):713-725. PubMed ID: 29786110
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. A novel SMAC mimetic APG-1387 exhibits dual antitumor effect on HBV-positive hepatocellular carcinoma with high expression of cIAP2 by inducing apoptosis and enhancing innate anti-tumor immunity.
    Pan W; Luo Q; Yan X; Yuan L; Yi H; Zhang L; Li B; Zhang Y; Sun J; Qiu MZ; Yang DJ
    Biochem Pharmacol; 2018 Aug; 154():127-135. PubMed ID: 29679556
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Inhibition of CREB binding protein-beta-catenin signaling down regulates CD133 expression and activates PP2A-PTEN signaling in tumor initiating liver cancer cells.
    Tang Y; Berlind J; Mavila N
    Cell Commun Signal; 2018 Mar; 16(1):9. PubMed ID: 29530069
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients.
    Yamauchi M; Urabe Y; Ono A; Miki D; Ochi H; Chayama K
    Int J Cancer; 2018 Apr; 142(7):1418-1426. PubMed ID: 29134647
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Rhabdoid tumor of the liver: Report of 6 pediatric cases treated at a single institute.
    Cornet M; De Lambert G; Pariente D; Planchon JM; Guettier C; Martelli H; Guérin F; Branchereau S
    J Pediatr Surg; 2018 Mar; 53(3):567-571. PubMed ID: 28966010
    [TBL] [Abstract] [Full Text] [Related]  


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