Terms: = Liver cancer AND GNA11, GNA-11, 2767, ENSG00000088256
37 results:
1. Emerging therapeutic strategies for metastatic uveal melanoma: Targeting driver mutations.
Liu XL; Run-Hua Z; Pan JX; Li ZJ; Yu L; Li YL
Pigment Cell Melanoma Res; 2024 May; 37(3):411-425. PubMed ID: 38411373
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2. Design, synthesis and evaluation of quinazoline derivatives as Gαq/11 proteins inhibitors against uveal melanoma.
Fan G; Liu L; Ye J; Xiao W; Xiong XF
Bioorg Chem; 2024 Feb; 143():107005. PubMed ID: 38043397
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3. Circulating Tumor DNA as a Prognostic Factor in Patients With Resectable Hepatic Metastases of Uveal Melanoma.
Mariani P; Bidard FC; Rampanou A; Houy A; Servois V; Ramtohul T; Pierron G; Chevrier M; Renouf B; Lantz O; Gardrat S; Vincent-Salomon A; Roman-Roman S; Rodrigues M; Piperno-Neumann S; Cassoux N; Stern MH; Renault S
Ann Surg; 2023 Oct; 278(4):e827-e834. PubMed ID: 36847256
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4. Autoantibodies to PAX5, PTCH1, and gna11 as Serological Biomarkers in the Detection of Hepatocellular Carcinoma in Hispanic Americans.
Qiu C; Ma Y; Wang B; Zhang X; Wang X; Zhang JY
Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835134
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5. Olutasidenib alone or with azacitidine in IDH1-mutated acute myeloid leukaemia and myelodysplastic syndrome: phase 1 results of a phase 1/2 trial.
Watts JM; Baer MR; Yang J; Prebet T; Lee S; Schiller GJ; Dinner SN; Pigneux A; Montesinos P; Wang ES; Seiter KP; Wei AH; De Botton S; Arnan M; Donnellan W; Schwarer AP; Récher C; Jonas BA; Ferrell PB; Marzac C; Kelly P; Sweeney J; Forsyth S; Guichard SM; Brevard J; Henrick P; Mohamed H; Cortes JE
Lancet Haematol; 2023 Jan; 10(1):e46-e58. PubMed ID: 36370742
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6. Paired comparisons of mutational profiles before and after brachytherapy in asian uveal melanoma patients.
Lee WS; Lee J; Choi JJ; Kang HG; Lee SC; Kim JH
Sci Rep; 2021 Sep; 11(1):18594. PubMed ID: 34545149
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7. Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for
Paradis JS; Acosta M; Saddawi-Konefka R; Kishore A; Gomes F; Arang N; Tiago M; Coma S; Lubrano S; Wu X; Ford K; Day CP; Merlino G; Mali P; Pachter JA; Sato T; Aplin AE; Gutkind JS
Clin Cancer Res; 2021 Jun; 27(11):3190-3200. PubMed ID: 33568347
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8. Research in practice: Therapeutic targeting of oncogenic GNAQ mutations in uveal melanoma.
Gaffal E
J Dtsch Dermatol Ges; 2020 Nov; 18(11):1245-1248. PubMed ID: 32954611
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9. Uveal melanoma.
Jager MJ; Shields CL; Cebulla CM; Abdel-Rahman MH; Grossniklaus HE; Stern MH; Carvajal RD; Belfort RN; Jia R; Shields JA; Damato BE
Nat Rev Dis Primers; 2020 Apr; 6(1):24. PubMed ID: 32273508
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10. Verification of EZH2 as a druggable target in metastatic uveal melanoma.
Jin B; Zhang P; Zou H; Ye H; Wang Y; Zhang J; Yang H; Pan J
Mol Cancer; 2020 Mar; 19(1):52. PubMed ID: 32127003
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11. Uveal melanoma: physiopathology and new in situ-specific therapies.
Souto EB; Zielinska A; Luis M; Carbone C; Martins-Gomes C; Souto SB; Silva AM
Cancer Chemother Pharmacol; 2019 Jul; 84(1):15-32. PubMed ID: 31079217
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12. Frequent GNAQ and GNA14 Mutations in Hepatic Small Vessel Neoplasm.
Joseph NM; Brunt EM; Marginean C; Nalbantoglu I; Snover DC; Thung SN; Yeh MM; Umetsu SE; Ferrell LD; Gill RM
Am J Surg Pathol; 2018 Sep; 42(9):1201-1207. PubMed ID: 29975248
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13. Germline mutation in the TP53 gene in uveal melanoma.
Hajkova N; Hojny J; Nemejcova K; Dundr P; Ulrych J; Jirsova K; Glezgova J; Ticha I
Sci Rep; 2018 May; 8(1):7618. PubMed ID: 29769598
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14. Prognostic value of chromosomal imbalances, gene mutations, and BAP1 expression in uveal melanoma.
Patrone S; Maric I; Rutigliani M; Lanza F; Puntoni M; Banelli B; Rancati S; Angelini G; Amaro A; Ligorio P; Defferrari C; Castagnetta M; Bandelloni R; Mosci C; DeCensi A; Romani M; Pfeffer U; Viaggi S; Coviello DA
Genes Chromosomes Cancer; 2018 Aug; 57(8):387-400. PubMed ID: 29689622
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15. Predictive Nomograms for Synchronous Distant Metastasis in Rectal cancer.
Gaitanidis A; Alevizakos M; Tsaroucha A; Tsalikidis C; Pitiakoudis M
J Gastrointest Surg; 2018 Jul; 22(7):1268-1276. PubMed ID: 29663304
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16. Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
Geng YD; Zhang C; Lei JL; Yu P; Xia YZ; Zhang H; Yang L; Kong LY
Biochem Pharmacol; 2017 Oct; 142():71-86. PubMed ID: 28673807
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17. Systematic genomic and translational efficiency studies of uveal melanoma.
Johnson CP; Kim IK; Esmaeli B; Amin-Mansour A; Treacy DJ; Carter SL; Hodis E; Wagle N; Seepo S; Yu X; Lane AM; Gragoudas ES; Vazquez F; Nickerson E; Cibulskis K; McKenna A; Gabriel SB; Getz G; Van Allen EM; 't Hoen PAC; Garraway LA; Woodman SE
PLoS One; 2017; 12(6):e0178189. PubMed ID: 28594900
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18. Prognostic impact of chromosomal aberrations and GNAQ, gna11 and BAP1 mutations in uveal melanoma.
Staby KM; Gravdal K; Mørk SJ; Heegaard S; Vintermyr OK; Krohn J
Acta Ophthalmol; 2018 Feb; 96(1):31-38. PubMed ID: 28444874
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19. The biology of uveal melanoma.
Amaro A; Gangemi R; Piaggio F; Angelini G; Barisione G; Ferrini S; Pfeffer U
Cancer Metastasis Rev; 2017 Mar; 36(1):109-140. PubMed ID: 28229253
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20. Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma.
Chua V; Lapadula D; Randolph C; Benovic JL; Wedegaertner PB; Aplin AE
Mol Cancer Res; 2017 May; 15(5):501-506. PubMed ID: 28223438
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