Terms: = Liver cancer AND JAK3, L-JAK, 3718, ENSG00000105639, P52333, JAKL, JAK-3, LJAK, JAK3_HUMAN
20 results:
1. HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents.
Waitman KB; de Almeida LC; Primi MC; Carlos JAEG; Ruiz C; Kronenberger T; Laufer S; Goettert MI; Poso A; Vassiliades SV; de Souza VAM; Toledo MFZJ; Hassimotto NMA; Cameron MD; Bannister TD; Costa-Lotufo LV; Machado-Neto JA; Tavares MT; Parise-Filho R
Eur J Med Chem; 2024 Jan; 263():115935. PubMed ID: 37989057
[TBL] [Abstract] [Full Text] [Related]
2. Leveraging Prior Healthy Participant Pharmacokinetic Data to Evaluate the Impact of Renal and Hepatic Impairment on Ritlecitinib Pharmacokinetics.
Purohit V; Huh Y; Wojciechowski J; Plotka A; Salts S; Antinew J; Dimitrova A; Nicholas T
AAPS J; 2023 Mar; 25(3):32. PubMed ID: 36977960
[TBL] [Abstract] [Full Text] [Related]
3. A cellular senescence-related classifier based on a tumorigenesis- and immune infiltration-guided strategy can predict prognosis, immunotherapy response, and candidate drugs in hepatocellular carcinoma.
Luo Y; Liu H; Fu H; Ding GS; Teng F
Front Immunol; 2022; 13():974377. PubMed ID: 36458010
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4. Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
Huang J; Zhou Y; Zhong X; Su F; Xu L
Oxid Med Cell Longev; 2022; 2022():3129155. PubMed ID: 35281458
[TBL] [Abstract] [Full Text] [Related]
5. Betulin, a Newly Characterized Compound in
Ahmadu AA; Delehouzé C; Haruna A; Mustapha L; Lawal BA; Udobre A; Baratte B; Triscornia C; Autret A; Robert T; Bulinski JC; Rousselot M; Simoes Eugénio M; Dimanche-Boitrel MT; Petzer JP; Legoabe LJ; Bach S
Molecules; 2021 Jul; 26(15):. PubMed ID: 34361750
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6. Establishment of Highly Transplantable Cholangiocarcinoma Cell Lines from a Patient-Derived Xenograft Mouse Model.
Vaeteewoottacharn K; Pairojkul C; Kariya R; Muisuk K; Imtawil K; Chamgramol Y; Bhudhisawasdi V; Khuntikeo N; Pugkhem A; Saeseow OT; Silsirivanit A; Wongkham C; Wongkham S; Okada S
Cells; 2019 May; 8(5):. PubMed ID: 31126020
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7. Interleukin-21 receptor gene polymorphism is associated with hepatitis B virus-related hepatocellular carcinoma in Chinese patients.
Liu T; Song J; Zhang M; Li S; Zhang J; Hu X; Zhao Z; Peng W; Wu Q; Bai H; Li Y; Lu X; Ying B
J Clin Lab Anal; 2019 Jun; 33(5):e22860. PubMed ID: 30758075
[TBL] [Abstract] [Full Text] [Related]
8. Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Kovaleva V; Geissler AL; Lutz L; Fritsch R; Makowiec F; Wiesemann S; Hopt UT; Passlick B; Werner M; Lassmann S
Mol Cancer; 2016 Oct; 15(1):63. PubMed ID: 27756406
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9. Targeted sequencing of cancer-associated genes in hepatocellular carcinoma using next generation sequencing.
Lu J; Yin J; Dong R; Yang T; Yuan L; Zang L; Xu C; Peng B; Zhao J; Du X
Mol Med Rep; 2015 Sep; 12(3):4678-4682. PubMed ID: 26096009
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10. Antitumor immunostimulatory activity of polysaccharides from Salvia chinensis Benth.
Shu G; Zhao W; Yue L; Su H; Xiang M
J Ethnopharmacol; 2015 Jun; 168():237-47. PubMed ID: 25858511
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11. A novel EGFP-expressing nude mice with complete loss of lymphocytes and NK cells to study tumor-host interactions.
Gotoh K; Kariya R; Matsuda K; Hattori S; Vaeteewoottacharn K; Okada S
Biosci Trends; 2014 Aug; 8(4):202-5. PubMed ID: 25224625
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12. Aberrant expression of NF-κB in liver fluke associated cholangiocarcinoma: implications for targeted therapy.
Seubwai W; Wongkham C; Puapairoj A; Khuntikeo N; Pugkhem A; Hahnvajanawong C; Chaiyagool J; Umezawa K; Okada S; Wongkham S
PLoS One; 2014; 9(8):e106056. PubMed ID: 25170898
[TBL] [Abstract] [Full Text] [Related]
13. Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.
De Mattos-Arruda L; Weigelt B; Cortes J; Won HH; Ng CKY; Nuciforo P; Bidard FC; Aura C; Saura C; Peg V; Piscuoglio S; Oliveira M; Smolders Y; Patel P; Norton L; Tabernero J; Berger MF; Seoane J; Reis-Filho JS
Ann Oncol; 2014 Sep; 25(9):1729-1735. PubMed ID: 25009010
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14. A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779.
Dugan BJ; Gingrich DE; Mesaros EF; Milkiewicz KL; Curry MA; Zulli AL; Dobrzanski P; Serdikoff C; Jan M; Angeles TS; Albom MS; Mason JL; Aimone LD; Meyer SL; Huang Z; Wells-Knecht KJ; Ator MA; Ruggeri BA; Dorsey BD
J Med Chem; 2012 Jun; 55(11):5243-54. PubMed ID: 22594690
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15. Somatic mutations of JAK1 and jak3 in acute leukemias and solid cancers.
Jeong EG; Kim MS; Nam HK; Min CK; Lee S; Chung YJ; Yoo NJ; Lee SH
Clin Cancer Res; 2008 Jun; 14(12):3716-21. PubMed ID: 18559588
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16. Synthesis, proton-affinity and anti-cancer properties of the prodigiosin-group natural products.
Manderville RA
Curr Med Chem Anticancer Agents; 2001 Aug; 1(2):195-218. PubMed ID: 12678767
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17. CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation.
Uckun FM; Thoen J; Chen H; Sudbeck E; Mao C; Malaviya R; Liu XP; Chen CL
Drug Metab Dispos; 2002 Jan; 30(1):74-85. PubMed ID: 11744615
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18. Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
Chen WS; Kung HJ; Yang WK; Lin Wc
Int J Cancer; 1999 Nov; 83(5):579-84. PubMed ID: 10521789
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19. Expression of Janus kinase 3 in human endothelial and other non-lymphoid and non-myeloid cells.
Verbsky JW; Bach EA; Fang YF; Yang L; Randolph DA; Fields LE
J Biol Chem; 1996 Jun; 271(24):13976-80. PubMed ID: 8662778
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20. The action of interleukin-2 receptor subunits defines a new type of signaling mechanism for hematopoietin receptors in hepatic cells and fibroblasts.
Morella KK; Lai CF; Kumaki S; Kumaki N; Wang Y; Bluman EM; Witthuhn BA; Ihle JN; Giri J; Gearing DP
J Biol Chem; 1995 Apr; 270(14):8298-310. PubMed ID: 7713938
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