Terms: = Liver cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Treatment
45 results:
1. NRF2 mutation enhances the immune escape of hepatocellular carcinoma by reducing STING activation.
Li C; Liang G; Yan K; Wang Y
Biochem Biophys Res Commun; 2024 Feb; 698():149536. PubMed ID: 38271834
[TBL] [Abstract] [Full Text] [Related]
2. Interplay of oxidative stress, cellular communication and signaling pathways in cancer.
Iqbal MJ; Kabeer A; Abbas Z; Siddiqui HA; Calina D; Sharifi-Rad J; Cho WC
Cell Commun Signal; 2024 Jan; 22(1):7. PubMed ID: 38167159
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3. Investigation of the effects of catharanthine and Q10 on Nrf2 and its association with MMP-9, MRP1, and Bcl-2 and apoptosis in a model of hepatocellular carcinoma.
Heidari-Kalvani N; Alizadeh-Fanalou S; Yarahmadi S; Fallah S; Alipourfard I; Farahmandian N; Barjesteh F; Bahreini E
Naunyn Schmiedebergs Arch Pharmacol; 2024 Apr; 397(4):2507-2522. PubMed ID: 37855932
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4. Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes.
Kowalik MA; Taguchi K; Serra M; Caddeo A; Puliga E; Bacci M; Koshiba S; Inoue J; Hishinuma E; Morandi A; Giordano S; Perra A; Yamamoto M; Columbano A
Hepatology; 2024 Apr; 79(4):829-843. PubMed ID: 37603610
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5. Camptothecin Sensitizes Hepatocellular Carcinoma Cells to Sorafenib- Induced Ferroptosis Via Suppression of Nrf2.
Elkateb AS; Nofal S; Ali SA; Atya HB
Inflammation; 2023 Aug; 46(4):1493-1511. PubMed ID: 37171695
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6. Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Zhu Y; Han Y; Wang W; Liang G; Qi J
J Ethnopharmacol; 2023 Jul; 311():116286. PubMed ID: 36965545
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7. Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C; Lu T; Liu M; Yuan X; Li D; Zhang J; Zhou L; Xu M
Phytomedicine; 2023 Mar; 111():154668. PubMed ID: 36657316
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8. Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease.
Liu P; Anandhan A; Chen J; Shakya A; Dodson M; Ooi A; Chapman E; White E; Garcia JG; Zhang DD
Redox Biol; 2023 Feb; 59():102570. PubMed ID: 36495698
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9. Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses.
Yuen VW; Chiu DK; Law CT; Cheu JW; Chan CY; Wong BP; Goh CC; Zhang MS; Xue HD; Tse AP; Zhang Y; Lau HY; Lee D; Au-Yeung RKH; Wong CM; Wong CC
J Hepatol; 2023 Feb; 78(2):376-389. PubMed ID: 36455783
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10. UBR7 inhibits HCC tumorigenesis by targeting keap1/Nrf2/Bach1/HK2 and glycolysis.
Zhao L; Kang M; Liu X; Wang Z; Wang Y; Chen H; Liu W; Liu S; Li B; Li C; Chang A; Tang B
J Exp Clin Cancer Res; 2022 Nov; 41(1):330. PubMed ID: 36419136
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11. Precision oncology for intrahepatic cholangiocarcinoma in clinical practice.
Tomczak A; Springfeld C; Dill MT; Chang DH; Kazdal D; Wagner U; Mehrabi A; Brockschmidt A; Luedde T; Naumann P; Stenzinger A; Schirmacher P; Longerich T
Br J Cancer; 2022 Nov; 127(9):1701-1708. PubMed ID: 35986087
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12. CRISPR-Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 pathway.
Chen J; Jiang S; Shao H; Li B; Ji T; Staiculescu D; He J; Zhao J; Cai L; Liang X; Xu J; Cai X
Sci China Life Sci; 2022 Oct; 65(10):1998-2016. PubMed ID: 35380342
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13. Identification of driver genes and target drugs-related genes in liver cancer based on targeted next generation sequencing.
Cui Y; Sun L; Wang H; Zhang Z; Dai H; Liu P
Neoplasma; 2022 Jan; 69(1):95-102. PubMed ID: 34704453
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14. STK11/LKB1 and keap1 mutations in non-small cell lung cancer: Prognostic rather than predictive?
Di Federico A; De Giglio A; Parisi C; Gelsomino F
Eur J Cancer; 2021 Nov; 157():108-113. PubMed ID: 34500370
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15. Molecular Mechanisms of Hepatoblastoma.
Zhang Y; Solinas A; Cairo S; Evert M; Chen X; Calvisi DF
Semin Liver Dis; 2021 Jan; 41(1):28-41. PubMed ID: 33764483
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16. The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-keap1-Nrf2 Antioxidant Pathway.
Wang F; Zhang Y; Shen J; Yang B; Dai W; Yan J; Maimouni S; Daguplo HQ; Coppola S; Gao Y; Wang Y; Du Z; Peng K; Liu H; Zhang Q; Tang F; Wang P; Gao S; Wang Y; Ding WX; Guo G; Wang F; Zong WX
Cell Mol Gastroenterol Hepatol; 2021; 11(5):1369-1385. PubMed ID: 33482392
[TBL] [Abstract] [Full Text] [Related]
17. Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) in autophagy-induced hepatocellular carcinoma.
Zhou J; Zhang X; Tang H; Yu J; Zu X; Xie Z; Yang X; Hu J; Tan F; Li Q; Lei X
Clin Chim Acta; 2020 Jul; 506():1-8. PubMed ID: 32109431
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18. Inhibitors of the protein-protein interaction between phosphorylated p62 and keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line.
Yasuda D; Ohe T; Takahashi K; Imamura R; Kojima H; Okabe T; Ichimura Y; Komatsu M; Yamamoto M; Nagano T; Mashino T
Free Radic Res; 2020 Dec; 54(11-12):859-871. PubMed ID: 32075457
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19. Nestin regulates cellular redox homeostasis in lung cancer through the keap1-Nrf2 feedback loop.
Wang J; Lu Q; Cai J; Wang Y; Lai X; Qiu Y; Huang Y; Ke Q; Zhang Y; Guan Y; Wu H; Wang Y; Liu X; Shi Y; Zhang K; Wang M; Peng Xiang A
Nat Commun; 2019 Nov; 10(1):5043. PubMed ID: 31695040
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20. Ferulic acid enhances the radiation sensitivity of lung and liver carcinoma cells by collapsing redox homeostasis: mechanistic involvement of Akt/p38 MAPK signalling pathway.
Das U; Manna K; Adhikary A; Mishra S; Saha KD; Sharma RD; Majumder B; Dey S
Free Radic Res; 2019 Oct; 53(9-10):944-967. PubMed ID: 31576765
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